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Table 3 Serum PFAS (medians, 25th–75th percentiles) according to Tanner stage, SES, age, and SDS for BMI, weight, and height

From: Associations between exposure to perfluoroalkyl substances and body fat evaluated by DXA and MRI in 109 adolescent boys

 

n (%)

PFOA (ng/mL)

PFOS (ng/mL)

PFHxS (ng/mL)

PFNA (ng/mL)

PFDA (ng/mL)

Median

25th-75th percentiles

Median

25th-75th percentiles

Median

25th-75th percentiles

Median

25th-75th percentiles

Median

25th-75th percentiles

Tanner stage

100

          

 1

20 (20)

3.05

2.58–3.58

8.57

6.70-–1.11

0.55

0.44–0.72

1.07

0.89–1.41

0.36

0.29–0.45

 2

33 (33)

2.99

2.22–4.27

7.03

5.40–9.95

0.54

0.44–0.68

0.95

0.72–1.19

0.33

0.24–0.41

 3

29 (29)

2.46

2.07–3.18

6.23

5.79–8.09

0.47

0.41–0.68

0.77

0.66–0.99

0.27

0.23–0.32

 4 + 5

18 (18)

2.26

1.85–3.36

6.04

5.12–7.43

0.43

0.31–0.51

0.85

0.71–1.08

0.27

0.23–0.32

P-value*

 

0.04

 

0.01

 

0.03

 

0.04

 

0.01

 

SES

108

          

 1

57 (52.7)

2.74

2.74–3.42

7.42

6.17–10.19

0.51

0.44–0.70

0.92

0.73–1.13

0.32

0.25–0.37

 2–4

51 (47.2)

3.00

2.19–3.63

6.23

5.40–7.90

0.46

0.37–0.54

0.94

0.73–1.20

0.29

0.24–0.36

P-value*

 

0.58

 

0.01

 

0.01

 

0.55

 

0.21

 

Age (years)

109

          

 10–11.9

36 (33.0)

3.13

2.28–4.31

6.92

6.06–8.59

0.52

0.44–0.64

0.94

0.69–1.22

0.33

0.26–0.37

 12.0–12.9

41 (37.6)

2.56

2.16–3.53

7.12

5.54–10.44

0.46

0.39–0.66

0.95

0.77–1.18

0.32

0.25–0.38

 13.0–15

32 (29.6)

2.68

2.00–3.30

6.63

5.85–8.71

0.48

0.41–0.66

0.82

0.71–1.04

0.28

0.25–0.36

P-value*

 

0.14

 

0.85

 

0.30

 

0.53

 

0.48

 

BMI SDS

109

          

  ≤ -1

22 (20.2)

2.77

2.17–3.13

6.90

5.97–10.53

0.47

0.43–0.56

0.96

0.68–1.20

0.27

0.25–0.40

  > -1 to ≤ 0

39 (35.8)

2.79

2.09–3.31

7.83

6.03–10.0

0.51

0.41–0.70

0.95

0.74–1.14

0.34

0.27–0.37

  > 0 to ≤ 1

32 (29.4)

3.08

2.27–4.99

6.56

5.87–9.29

0.52

0.42–0.67

0.91

0.73–1.42

0.31

0.23–0.40

  > 1

16 (14.7)

2.60

1.89–3.62

5.86

4.97–6.73

0.41

0.32–0.60

0.78

0.73-–1.03

0.27

0.21–0.30

P-value*

 

0.39

 

0.01

 

0.25

 

0.66

 

0.06

 

Weight SDS

109

          

  ≤ -1

19 (17.4)

2.76

2.32–3.22

7.90

5.91–10.78

0.50

0.43–0.68

1.11

0.88–1.24

0.33

0.27–0.45

  > -1 to ≤ 0

35 (32.1)

2.90

2.19–3.39

7.91

6.12–10.45

0.52

0.43–0.65

0.95

0.72–1.14

0.34

0.27–0.37

  > 0 to ≤ 1

37 (33.9)

2.79

2.07–4.08

6.52

5.41–7.93

0.50

0.41–0.69

0.82

0.69–1.22

0.27

0.22–0.34

  > 1

18 (16.5)

2.53

1.85–3.62

6.14

5.14–7.06

0.41

0.34–0.58

0.81

0.75–1.07

0.28

0.23–0.33

P-value*

 

0.79

 

0.01

 

0.13

 

0.40

 

0.02

 

Height SDS

109

          

  ≤ -1

15 (13.8)

3.17

2.69–7.14

10.11

7.12–13.03

0.68

0.54–0.85

1.11

0.91–1.27

0.36

0.31–0.52

  > -1 to ≤ 0

33 (30.3)

2.84

2.24–3.44

7.91

5.99–10.12

0.51

0.43–0.65

0.95

0.69–1.21

0.34

0.26–0.40

  > 0 to ≤ 1

37 (33.9)

2.92

2.19–3.62

6.23

5.57–7.48

0.47

0.40–0.65

0.90

0.73–1.07

0.29

0.25–0.34

  > 1

24 (22.0)

2.37

1.89–3.06

6.32

5.31–7.13

0.43

0.38–0.54

0.79

0.63–1.09

0.26

0.21–0.33

P-value*

 

0.06

 

 < 0.01

 

0.01

 

0.09

 

0.01

 
  1. Data are presented as medians and 25–75 percentiles. SES Socioeconomic status, BMI Body mass index, SDS Standard deviation score, PFAS Polyfluoroalkyl substances, PFOA Perfluorooctanoic acid, PFOS Perfluorooctane sulfonic acid, PFHxS Perfluorohexane sulfonic acid, PFNA Perfluorononanoic acid, PFDA Perfluorodecanoic acid
  2. * Differences in PFAS concentrations between subgroups were tested using Kruskal–Wallis test. P-values < 0.05 were considered significant and highlighted in bold
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Environmental Health

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