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Table 5 Adjusted linear regression coefficients and 95% confidence intervals for newborn and maternal telomere length (T/S ratio) with an interquartile range increase in second trimester PFAS (ng/mL) and PBDE (ng/g lipid) concentrations in maternal serum

From: Mixture effects of prenatal exposure to per- and polyfluoroalkyl substances and polybrominated diphenyl ethers on maternal and newborn telomere length

 

Newborn Telomere Length (N = 292)

Maternal Telomere Length (N = 110)

Beta

95% CI

Beta

95% CI

Per- and poly-fluoroalkyl substances

 PFNA

0.01

(-0.03, 0.04)

0.03

(-0.01, 0.07)

 PFOA

0.01

(-0.03, 0.06)

0.05

(0.01, 0.10)

 PFOS

-0.01

(-0.05, 0.03)

0.03

(-0.01, 0.08)

 PFHxS

-0.01

(-0.05, 0.04)

0.04

(-0.02, 0.09)

 Me-PFOSA-AcOH

0.00

(-0.03, 0.03)

0.01

(-0.02, 0.04)

 PFDeA

0.01

(-0.03, 0.04)

0.03

(-0.02, 0.07)

 PFUdA

0.00

(-0.05, 0.04)

0.04

(-0.03, 0.1)

Polybrominated diphenyl ethers

 BDE-47

0.03

(0.00, 0.07)

0.01

(-0.02, 0.04)

 BDE-99

0.03

(-0.01, 0.06)

0.01

(-0.03, 0.04)

 BDE-153

0.00

(-0.03, 0.04)

-0.02

(-0.06, 0.01)

 BDE-100

0.02

(-0.01, 0.06)

-0.01

(-0.04, 0.03)

  1. Abbreviations: CI Confidence interval
  2. Adjusted for maternal age, race/ethnicity, education, parity, and pre-pregnancy body mass index
  3. Note: There are 326 pregnant participants, of which there are 76 maternal–fetal unit pairs