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Table 5 Adjusted linear regression coefficients and 95% confidence intervals for newborn and maternal telomere length (T/S ratio) with an interquartile range increase in second trimester PFAS (ng/mL) and PBDE (ng/g lipid) concentrations in maternal serum

From: Mixture effects of prenatal exposure to per- and polyfluoroalkyl substances and polybrominated diphenyl ethers on maternal and newborn telomere length

  Newborn Telomere Length (N = 292) Maternal Telomere Length (N = 110)
Beta 95% CI Beta 95% CI
Per- and poly-fluoroalkyl substances
 PFNA 0.01 (-0.03, 0.04) 0.03 (-0.01, 0.07)
 PFOA 0.01 (-0.03, 0.06) 0.05 (0.01, 0.10)
 PFOS -0.01 (-0.05, 0.03) 0.03 (-0.01, 0.08)
 PFHxS -0.01 (-0.05, 0.04) 0.04 (-0.02, 0.09)
 Me-PFOSA-AcOH 0.00 (-0.03, 0.03) 0.01 (-0.02, 0.04)
 PFDeA 0.01 (-0.03, 0.04) 0.03 (-0.02, 0.07)
 PFUdA 0.00 (-0.05, 0.04) 0.04 (-0.03, 0.1)
Polybrominated diphenyl ethers
 BDE-47 0.03 (0.00, 0.07) 0.01 (-0.02, 0.04)
 BDE-99 0.03 (-0.01, 0.06) 0.01 (-0.03, 0.04)
 BDE-153 0.00 (-0.03, 0.04) -0.02 (-0.06, 0.01)
 BDE-100 0.02 (-0.01, 0.06) -0.01 (-0.04, 0.03)
  1. Abbreviations: CI Confidence interval
  2. Adjusted for maternal age, race/ethnicity, education, parity, and pre-pregnancy body mass index
  3. Note: There are 326 pregnant participants, of which there are 76 maternal–fetal unit pairs