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Table 7 Associations between urine biomarkers of chemical exposure and specific IgEd in adult participants

From: Exposure to environmental phenols and parabens, and relation to body mass index, eczema and respiratory outcomes in the Norwegian RHINESSA study

  Sex: male vs female Specific IgEd Interactionc
  ∆/OR CI p ∆/OR CI p p
Sum of parabena -0.66 (-0.80,-0.51)  < 0.001 -0.08 (-0.06,0.23) 0.3 0.03
Methylparabena -1.68 (-2.02,-1.34)  < 0.001 0.22 (-0.11,0.55) 0.3 0.2
Butylparabenb 0.14 (0.09,0.25)  < 0.001 0.66 (0.42,1.03) 0.07 0.5
Propylparabena -2.14 (-2.51,-1.77)  < 0.001 0.07 (-0.31,0.45) 0.7 0.5
Ethylparabena -1.06 (-1.35,-0.76)  < 0.001 -0.06 (-0.36,0.23) 0.4 0.7
Benzophenone-3a -1.54 (-1.94,-1.14)  < 0.001 -0.23 (-0.63,0.18) 0.3 1.0
Bisphenol Sa -0.09 (-0.22,0.04) 0.2 0.18 (-0.04,0.32) 0.01 0.3
Bisphenol Fa -0.13 (-0.33,0.06) 1.3 -0.02 (-0.22,0.18) 0.8 0.1
Bisphenol Aa 0.19 (0.04,0.34) 0.01 0.11 (-0.04,0.26) 0.1 0.4
2,4- DCPa -0.06 (-0.19,0.08) 0.4 0.15 (-0.01,0.29) 0.03 0.6
2,5 –DCPb 1.89 (1.24 2.88) 0.03 0.84 (0.57,1.24) 0.4 0.9
Triclosanb 0.74 (0.46,1.19) 0.2 1.05 (0.67,1.63) 0.8 0.06
Triclocarbanb 0.68 (0.27,1.70) 0.4 1.06 (0.39,2.10) 0.4 0.3
  1. aMultiple linear or blogistic regression including sex and variable for IgE, adjusted for BMI, age, smoking, and time of day of urine sampling. c Interaction term between sex and IgE. dIgE positivity defined by IgE ≥ 0.35 kU/L to at least 1 of 5 allergens tested (cat, timothy grass, Cladosporium, birch, and house dust)