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Table 1 Demographic, functional, clinical and laboratory characteristics for all patients and for those with telomere length ratio measurement

From: Long-term personal air pollution exposure and risk for acute exacerbation of idiopathic pulmonary fibrosis

Personal & health characteristics All patients
(n = 118)
Patients with telomere length ratio (n = 36) Patients without telomere length ratio (n = 82) p-valuea
Gender (male; n, %) 88 (74.6) 27 (75.0) 61 (74.4) 0.9441
Age (years; mean, SD) 72 (8.3) 72 (8.0) 72 (8.4) 0.8862
Smoking status (n, %)
No smoker 31 (26.3) 11 (30.6) 20 (24.4) 0.7441
Ex smoker 78 (66.1) 22 (61.1) 56 (68.3)
Current smoker 9 (7.6) 3 (8.3) 6 (7.3)
FVC (most recent, %; mean, SD) 71.2 (20.2) 79.5 (18.8) 67.3 (19.8) 0.0042
DLCO (most recent, %; mean, SD) 41.4 (19.1) 46.0 (17.2) 39.7 (20.1) 0.1332
GAP stage (n, %)
I 33 (28.0) 13 (38.2) 20 (26.7)  
II 51 (43.2) 15 (44.1) 36 (48.0) 0.4251
III 25 (21.2) 6 (17.7) 19 (25.3)  
Number of exacerbations (mean, SD) 0.7 (1.0) 0.6 (0.8) 0.8 (1.0) 0.2942
Exacerbation (yes; n, %) 55 (46.6) 14 (38.9) 41 (50.0) 0.2171
Telomere length ratio (mean, SD) 0.79 (0.35) 0.79 (0.35) - -
Antifibrotic therapy (yes; n, %) 44 (37.3) 12 (33.3) 32 (39.0) 0.6711
  1. Abbreviations: FVC Forced Vital Capacity, DLCO Diffusing Capacity of the lung for carbon monoxide, SD Standard Deviation
  2. p-valuea: assessing differences between patients with/without telomere length ratio measurement
  3. 1chi-square test
  4. 2independent samples t-test