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Table 1 Demographic, functional, clinical and laboratory characteristics for all patients and for those with telomere length ratio measurement

From: Long-term personal air pollution exposure and risk for acute exacerbation of idiopathic pulmonary fibrosis

Personal & health characteristics

All patients

(n = 118)

Patients with telomere length ratio (n = 36)

Patients without telomere length ratio (n = 82)

p-valuea

Gender (male; n, %)

88 (74.6)

27 (75.0)

61 (74.4)

0.9441

Age (years; mean, SD)

72 (8.3)

72 (8.0)

72 (8.4)

0.8862

Smoking status (n, %)

No smoker

31 (26.3)

11 (30.6)

20 (24.4)

0.7441

Ex smoker

78 (66.1)

22 (61.1)

56 (68.3)

Current smoker

9 (7.6)

3 (8.3)

6 (7.3)

FVC (most recent, %; mean, SD)

71.2 (20.2)

79.5 (18.8)

67.3 (19.8)

0.0042

DLCO (most recent, %; mean, SD)

41.4 (19.1)

46.0 (17.2)

39.7 (20.1)

0.1332

GAP stage (n, %)

I

33 (28.0)

13 (38.2)

20 (26.7)

 

II

51 (43.2)

15 (44.1)

36 (48.0)

0.4251

III

25 (21.2)

6 (17.7)

19 (25.3)

 

Number of exacerbations (mean, SD)

0.7 (1.0)

0.6 (0.8)

0.8 (1.0)

0.2942

Exacerbation (yes; n, %)

55 (46.6)

14 (38.9)

41 (50.0)

0.2171

Telomere length ratio (mean, SD)

0.79 (0.35)

0.79 (0.35)

-

-

Antifibrotic therapy (yes; n, %)

44 (37.3)

12 (33.3)

32 (39.0)

0.6711

  1. Abbreviations: FVC Forced Vital Capacity, DLCO Diffusing Capacity of the lung for carbon monoxide, SD Standard Deviation
  2. p-valuea: assessing differences between patients with/without telomere length ratio measurement
  3. 1chi-square test
  4. 2independent samples t-test