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Table 3 Long-term personal exposure to concentrations of air pollutants and risk of AE-IPF. Results reported from logistic regression models: Odds Ratio (OR) & 95% C.I., after adjusting for gender, age, smoking habits, recent FVC, recent DLCO and antifibrotic therapy. a also adjusting for telomere length ratio; b Ο3: also adjusting for PM2.5

From: Long-term personal air pollution exposure and risk for acute exacerbation of idiopathic pulmonary fibrosis

Results reported per (10 μg/m3): All patients Patients residing in the Greater Athens Area (n = 66) Patients residing out of the Greater Athens Area (n = 52)
OR
(95% CI)
p-value OR (95% CI) p-value OR (95% CI) p-value
1O3 0.60 (0.43 to 0.86) 0.005** 0.57 (0.27 to 1.17) 0.126 0.76 (0.28 to 2.06) 0.590
a 2O3 0.27 (0.07 to 1.00) 0.050  
b 1O3 0.55 (0.27 to 1.13) 0.105 0.42 (0.10 to 1.81) 0.245 0.78 (0.27 to 2.29) 0.654
b 2O3 0.26 (0.01 to 1.05) 0.052     
1NO2 1.52 (1.15 to 2.00) 0.003** 1.58 (0.88 to 2.87) 0.128 3.89 (0.75 to 20.3) 0.106
a 2NO2 2.64 (0.99 to 7.05) 0.053  
1PM2.5 2.21 (1.16 to 4.20) 0.016* 2.01 (0.56 to 7.12) 0.282 1.67 (0.08 to 36.5) 0.743
a 2PM2.5 2.78 (0.35 to 22.2) 0.335  
1PM10 2.18 (1.15 to 4.15) 0.017* 1.96 (0.57 to 6.71) 0.285 1.93 (0.12 to 29.9) 0.637
a 2PM10 2.35 (0.31 to 17.9) 0.410  
  1. Abbreviations: FVC Forced Vital Capacity, DLCO Diffusing Capacity of the lung for carbon monoxide, O3 ozone, PM particulate matter, NO2 nitrogen dioxide
  2. 1All patients (n = 118)
  3. 2All patients with telomere length ratio measurements (n = 36)
  4. * statistically significant at a = 5%
  5. ** statistically significant at a = 1%