Table 1 Case control study on MM in Casale Monferrato area. Risk of MM of the pleura in relation to the distance of longest-held residence (after exclusion of 20 years before the date of diagnosis) from the AC plant. Absolute and relative frequencies of distance categories and median [interquartile range] of distance. Logistic models adjusted by age, sex, type of interview (*) and age, sex, type of interview and occupational and domestic asbestos exposure as continuous covariate (**) or age, sex, type of interview and domestic asbestos exposure as continuous covariate (***); odds ratios (OR), 95% confidence intervals (in brackets) and Akaike Information Criterion (AIC)

All subjects

Distance from the AC plant (km)

All

N = 518

Cases

N = 196

Controls

N = 322

OR adjusted*

OR adjusted**

0–5

237 (45.75)

126 (64.29)

111 (34.47)

10.91 (5.32–22.38)

10.81 (5.26–22.21)

5–10

75 (14.48)

40 (20.41)

35 (10.87)

10.48 (4.54–24.2)

10.42 (4.51–24.07)

10–15

85 (16.41)

18 (9.18)

67 (20.81)

2.2 (0.9–5.33)

2.2 (0.9–5.34)

 > 15

121 (23.36)

12 (6.12)

109 (33.85)

Ref

Ref

AIC

513.71

515.43

Distance, Km

6.06 [12.25]

2.10 [5.9]

11.32 [15.77]

0.87 (0.84–0.91)

0.88 (0.84–0.91)

AIC

514.91

516.61

Non-occupationally exposed subjects

Distance from the AC plant (km)

All

N = 263

Cases

N = 82

Controls

N = 181

OR adjusted*

OR adjusted***

0–5

128 (48.67)

59 (71.95)

69 (38.12)

13.73 (4.57–41.32)

12.66 (4.19–38.28)

5–10

30 (11.41)

12 (14.63)

18 (9.94)

8.5 (2.29–31.61)

7.15 (1.87–27.36)

10–15

39 (14.83)

6 (7.32)

33 (18.23)

2.81 (0.7–11.29)

2.47 (0.61–10.04)

 > 15

66 (25.10)

5 (6.10)

61 (33.70)

Ref

Ref

AIC

251.83

249.96

Distance, Km

5.29 [13.56]

2.03 [4.59]

10.36 [15.86]

0.86 (0.81–0.91)

0.86 (0.81–0.91)

AIC

247.18

244.89