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Table 4 Effect modification of the associations between long-term exposure to PM2.5 and deep vein thrombosis and pulmonary embolism in RoLS. Results are expressed as hazard ratios (HR) with relative 95% confidence intervals per 10 µg/m3 increases of pollutant

From: Long-term exposure to air pollution and risk of venous thromboembolism in a large administrative cohort

  DVT   PE  
  HR 95%aCI P-value** HR 95%CI P-value
Overalla 1.082 0.992 1.181   1.136 0.994 1.298  
Age class
  < 70 y 1.109 0.994 1.237 - 1.192 0.998 1.424 -
  > 70 y 1.032 0.899 1.185 0.043 1.081 0.890 1.315 0.837
Sex
 Females 1.130 0.995 1.285 - 1.168 0.958 1.425 -
 Males 1.046 0.933 1.173 0.799 1.112 0.933 1.325 0.772
Cardiovascular
 No 1.092 0.994 1.199 - 1.180 1.023 1.361 -
 Yes 1.028 0.824 1.284 0.792 0.896 0.629 1.275 0.185
AMI
 No 1.079 0.986 1.181 - 1.117 0.972 1.283 -
 Yes 1.130 0.810 1.577 0.459 1.407 0.882 2.245 0.901
Hypertension
 No 1.079 0.986 1.182 - 1.175 1.023 1.349 -
 Yes 1.112 0.834 1.481 0.777 0.777 0.487 1.240 0.071
Diabetes
 No 1.084 0.984 1.193 - 1.156 0.999 1.338 -
 Yes 1.078 0.887 1.310 0.554 1.044 0.766 1.423 0.539
Hyperlipidaemia
 No 1.075 0.984 1.173 - 1.144 1.000 1.308 -
 Yes 1.596 0.861 2.960 0.127 0.700 0.229 2.136 0.505
COPD
 No 1.122 1.017 1.238 - 1.131 0.968 1.322 -
 Yes 0.963 0.807 1.149 0.005 1.154 0.900 1.478 0.273
Cancer
 No 1.075 0.981 1.178 - 1.119 0.968 1.294 -
 Yes 1.123 0.861 1.465 0.080 1.230 0.892 1.696 0.799
  1. aAdjusted as Model 2
  2. **p-values from Wald test