Skip to main content

Table 3 Association between PM coarse, PM10 traffic and PM10 non-traffic exposure and biomarkers

From: Air pollution and biomarkers of cardiovascular disease and inflammation in the Malmö Diet and Cancer cohort

  

PM coarse

PM10 traffic

PM10 non-traffic

Increment of exposure

 

5 μg/m3

 

1 μg/m3

 

1 μg/m3

 
  

β-Coefficient (95% CI)

P value*

β-Coefficient (95% CI)

P value*

β-Coefficient (95% CI)

P value*

Leukocytes

M0

0.01 (− 0.016–0.036)

0.27

0.0081 (0.0033–0.013)

0.001

0.0067 (− 0.033–0.046)

0.74

 

M1

0.01 (− 0.018–0.038)

0.47

0.0012 (− 0.0034–0.0059)

0.6

−0.0064 (− 0.044–0.031)

0.74

 

M2

− 0.0031 (− 0.034–0.028)

0.85

− 0.0013 (− 0.0065–0.004)

0.64

−0.013 (− 0.052–0.025)

0.5

NLR

M0

0.034 (− 0.0089–0.077)

0.12

0.005 (− 0.0022–0.012)

0.17

0.027 (− 0.031–0.085)

0.36

 

M1

0.023 (− 0.022–0.067)

0.32

0.0031 (− 0.0042–0.011)

0.41

0.011 (− 0.049–0.07)

0.73

 

M2

0.031 (− 0.02–0.081)

0.24

0.0039 (− 0.0046–0.012)

0.37

0.0057 (− 0.057–0.069)

0.86

CRP

M0

0.13 (− 0.004–0.26)

0.058

0.019 (− 0.0024–0.041)

0.082

−0.086 (− 0.26–0.087)

0.33

 

M1

0.057 (− 0.067–0.182)

0.37

0.0057 (− 0.015–0.026)

0.59

0.0017 (− 0.16–0.17)

0.98

 

M2

−0.014 (− 0.15–0.13)

0.85

−0.0074 (− 0.031–0.016)

0.54

−0.046 (− 0.22–0.13)

0.61

SuPAR

M0

0.059 (0.025–0.094)

0.001

0.011 (0.0052–0.017)

< 0.001

−0.017 (− 0.064–0.03)

0.48

 

M1

0.019 (− 0.014–0.053)

0.25

0.0039 (− 0.0016–0.0093)

0.17

−0.0089 (− 0.053–0.035)

0.69

 

M2

0.0048 (− 0.032–0.042)

0.8

0.0016 (− 0.0045–0.0077)

0.61

−0.011 (− 0.057–0.034)

0.63

LP-PLA2

M0

0.0028 (− 0.033–0.038)

0.88

0.0008 (− 0.0052–0.0067)

0.8

0.0056 (− 0.042–0.053)

0.82

 

M1

−0.015 (− 0.051–0.021)

0.42

−0.0023 (− 0.0083–0.0036)

0.44

0.0051 (− 0.043–0.053)

0.84

 

M2

− 0.0053 (− 0.046–0.035)

0.8

−0.0003 (− 0.007–0.0065)

0.94

0.026 (− 0.024–0.076)

0.31

Ceruloplasmin

M0

0.039 (0.012–0.066)

0.005

0.0042 (− 0.0003–0.0087)

0.065

0.035 (− 0.0014–0.072)

0.06

 

M1

0.036 (0.0083–0.063)

0.011

0.0035 (− 0.001–0.0081)

0.13

0.039 (0.0021–0.076)

0.038

 

M2

0.024 (− 0.0071–0.055)

0.13

0.001 (− 0.0042–0.0061)

0.71

0.026 (− 0.013–0.065)

0.18

Orosomucoid

M0

0.045 (0.0088–0.081)

0.015

0.012 (− 0.0031–0.027)

0.12

0.032 (− 0.016–0.081)

0.19

 

M1

0.03 (− 0.0054–0.065)

0.097

0.002 (− 0.0038–0.0079)

0.5

0.05 (0.0027–0.097)

0.038

 

M2

0.017 (− 0.022–0.056)

0.39

−0.0013 (− 0.017–0.015)

0.87

0.046 (− 0.0032–0.095)

0.067

Haptoglobin

M0

0.073 (0.014–0.13)

0.015

0.012 (0.0025–0.022)

0.014

0.026 (− 0.053–0.11)

0.52

 

M1

0.038 (− 0.02–0.096)

0.2

0.006 (− 0.0036–0.016)

0.22

0.029 (− 0.049–0.11)

0.46

 

M2

0.011 (− 0.055–0.076)

0.75

0.0014 (− 0.0095–0.012)

0.8

0.013 (− 0.069–0.094)

0.76

C3

M0

0.034 (0.0073–0.061)

0.013

0.0037 (− 0.0007–0.0081)

0.1

0.0047 (− 0.032–0.041)

0.8

 

M1

0.033 (0.0076–0.058)

0.011

0.0032 (− 0.001–0.0074)

0.14

0.033 (− 0.0008–0.067)

0.055

 

M2

0.016 (− 0.012–0.044)

0.26

−0.0001 (− 0.0048–0.0045)

0.96

0.022 (− 0.013–0.057)

0.21

alpha-1-antitrypsin

M0

0.045 (0.014–0.075)

0.004

0.0055 (0.0004–0.011)

0.033

0.035 (− 0.0059–0.076)

0.094

 

M1

0.033 (0.0026–0.064)

0.034

0.0036 (− 0.0015–0.0087)

0.17

0.032 (−0.0086–0.074)

0.12

 

M2

0.014 (−0.021–0.049)

0.44

−0.0001 (− 0.006–0.0057)

0.97

0.019 (− 0.025–0.062)

0.39

  1. *p < 0.05 bolded. M0: adjusted for age and sex. M1: adjusted for age, sex, alcohol consumption, BMI, smoking status, and education. M2: adjusted for age, sex, alcohol consumption, BMI, smoking status, education, number of cigarettes, mean area income, occupational class, leisure-time physical activity, systolic blood pressure, ApoA/ApoB1 ratio, prevalent diabetes, country of birth, cohabitation, statin use and NSAID use