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Table 2 Associations (95% CI) between biomarkers and birth weight (grams) and gestational age (weeks) overall

From: Maternal serum concentrations of one-carbon metabolism factors modify the association between biomarkers of arsenic methylation efficiency and birth weight

 

Unadjusted β (95% CI)

Model 1a β (95% CI)

Model 2b β (95% CI)

Model 3c β (95% CI)

Birth weight (grams)

 % U-iAs

−6.11 (− 22.80, 10.58)

−4.61 (− 21.21, 11.98)

−5.55 (− 22.28, 11.19)

− 3.65 (− 21.25, 13.96)

 % U-MMAs

−20.84 (− 42.65, 0.97)

−23.09 (− 44.54, − 1.64)

− 22.92 (−44.50, − 1.35)

− 21.07 (−45.24, 3.11)

 % U-DMAs

7.62 (− 3.16, 18.40)

7.56 (− 3.11, 18.22)

7.91 (− 2.82, 18.65)

6.42 (− 5.21, 18.05)

 C-tAs (pg As/mL)

−51.47 (− 225.84, 122.90)

− 233.17 (− 577.60, 111.26)

−238.72 (− 585.25, 107.82)

− 385.54 (− 892.83, 121.76)

Gestational age (weeks)

 % U-iAs

0.01 (−0.04, 0.05)

0 (− 0.04, 0.05)

0.01 (− 0.04, 0.05)

0 (− 0.05, 0.05)

 % U-MMAs

− 0.03 (− 0.09, 0.02)

−0.04 (− 0.10, 0.02)

−0.04 (− 0.10, 0.02)

−0.03 (− 0.10, 0.03)

 % U-DMAs

0.01 (− 0.02, 0.03)

0.01 (− 0.02, 0.04)

0.01 (− 0.02, 0.04)

0.01 (− 0.02, 0.04)

 C-tAs (pg As/mL)

−0.06 (− 0.54, 0.41)

0.87 (0, 1.74)

0.86 (− 0.01, 1.74)

0.90 (− 0.31, 2.12)

  1. aModel 1 adjusts for smoking status during pregnancy, maternal age, and U-tAs
  2. bModel 2 adjusts for smoking status during pregnancy, maternal age, U-tAs, B12, folate, and homocysteine
  3. cModel 3 adjusts for smoking status during pregnancy, maternal age, and U-tAs and excludes mothers reporting recent seafood intake