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Table 4 Odd Ratios (OR) for presenting high TSH, low FT4 and low FT3 according to Air pollutants concentrations

From: Ambient air pollution and thyroid function in Spanish adults. A nationwide population-based study (Di@bet.es study)

 

TSH>4.66 µUI/mL (p95)

FT4≤11.97 pmol/L (p5)

FT3≤3.93 pmol/L (p5)

 

OR

CI 95%

p

OR

CI 95%

p

OR

CI 95%

p

PM2.5

  Crude

1.20

0.99-1.45

0.060

1.30

1.08-1.57

0.006

1.34

1.11-1.62

0.002

  Multivariate

1.24

1.01-1.52

0.043

1.25

1.02-1.54

0.032

1.48

1.19-1.84

<0.001

NO2

  Crude

1.13

0.98-1.31

0.094

1.12

0.97-1.29

0.122

1.02

0.88-1.19

0.797

  Multivariate

1.13

0.97-1.32

0.115

1.15

0.99-1.35

0.074

1.00

0.84-1.18

0.997

  1. ORs, 95% CI and p values were calculated by logistic regression per interquartile range (IQR) increase in air pollutants concentrations (PM2.5: 4.86 μg/m3, NO2: 12.62 μg/m3).
  2. In bold: ORs with p values <0.05
  3. #Multivariate model: Adjusted to age, sex, urinary iodine, BMI, education level, smoking status and ambient temperature
  4. PM2.5 Particles with an aerodynamic diameter of less than 2.5 microns, NO2 nitrogen dioxide