Table 2 Grouping methods developed or used by non-regulatory organizations
Organization | Chemical/class | Grouping method |
|---|---|---|
Organization for Economic Co-operation and Development | Chemicals in general [34] | Structural similarity |
National Academy of Sciences | Phthalates [22] | Common adverse outcomes—anti-androgenicity regardless of mechanism of action |
California Environmental Contaminant Biomonitoring Program | Twelve chemical groups have been added to the biomonitoring program [35] | Structural and functional characteristics |
US Cosmetic Ingredient Review | Cosmetic products [36] | Structural similarity and physical-chemical properties |
Flavor and Extract Manufacturer Association | Flavoring substances, spices [37] | Structural similarity and metabolic fate |
Joint Expert Committee on Food Additives (WHO/FAO) | Food ingredients, chemicals and contaminants [38] | Structural similarity |