Table 2 Mean #IVdays within and beyond 4 km of a PCS in pwCF in the UK in 2016. p-value < 0.05 are shown in bold
#IVdays | ||||
|---|---|---|---|---|
Characteristics | n (%) | mean (SD) | mean (SD) | p-value |
≤ 4 km | > 4 km | |||
(n = 9,361 (100%) | (n = 1,015;10.8%) | (n = 8,346; 89.2%) | ||
Age (years) | 0.291 | |||
Children < 6 | 1,561 (16.7) | 5.5 (9.8) | 5.1 (11.2) | |
6-15 | 2,370 (25.3) | 12.7 (21.8) | 12.4 (20.9) | |
Adults ≥ 16 | 5,430 (58.0) | 22.4 (34.2) | 21.0 (32.7) | |
Sex | 0.003 | |||
Female | 4,371 (46.7) | 22.0 (35.1) | 18.7 (30.5) | |
Male | 4,990 (53.3) | 14.2 (24.4) | 13.9 (25.4) | |
Genotype | 0.004 | |||
Homozygous F508del | 4,603 (49.2) | 22.9 (38.1) | 17.7 (29.9) | |
F508del/MF | 1,822 (19.5) | 12.3 (21.7) | 12.4 (25.0) | |
RF/other | 1,070 (11.4) | 8.4 (22.1) | 8.4 (17.0) | |
F508del/other | 663 (7.1) | 21.0 (30.1) | 19.4 (30.1) | |
Gating/anya | 583 (6.2) | 11.8 (19.6) | 19.0 (27.6) | |
MF/MF | 298 (3.2) | 18.7 (30.3) | 11.0 (20.2) | |
Other/other | 176 (1.9) | 10.6 (22.8) | 12.2 (32.3) | |
MF/other | 146 (1.6) | 5.7 (19.7) | 6.2 (16.5) | |
P. aeruginosa culture | < 0.001 | |||
Negative | 5,108 (55.2) | 77.6 (22.4) | 80.4 (21.4) | |
Positive | 4,139 (44.8) | 61.2 (24.0) | 62.8 (23.4) | |
Deprivation quintile (Townsend) | 0.005 | |||
Q1 (least deprived) | 1,905 (20.4) | 15.2 (24.6) | 14.1 (25.4) | |
Q2 | 1,948 (20.8) | 16.8 (27.1) | 15.6 (28.1) | |
Q3 | 1,982 (21.2) | 15.7 (32.1) | 15.4 (26.4) | |
Q4 | 1,868 (20.0) | 17.7 (30.5) | 16.6 (28.8) | |
Q5 (most deprived) | 1,658 (17.7) | 22.0 (33.6) | 19.4 (31.5) | |
Rural and Urban | 0.004 | |||
Rural | 1,794 (19.2) | 16.0 (25.1) | 15.3 (26.4) | |
Urban | 7,567 (80.8) | 18.1 (30.7) | 16.3 (28.4) | |