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Table 2 Crudea and Adjustedb Rate Ratios (RRs) and 95% Confidence Intervals (CIs) for the Association between Paraquat Density and ESRD Incidence Based on 20-Year, 15-Year, 10-Year and 5-Year Exposure Lags

From: An ecological study regarding the association between paraquat exposure and end stage renal disease

 

20 Year

(2016-2018 cases)

15 Year

(2011-2018 cases)

10 Year

(2010-2018 cases)

5 Year

(2010-2018 cases)

Crude RR

(95% CI)

Adjusted RR

(95% CI)

Crude RR

(95% CI)

Adjusted RR

(95% CI)

Crude RR

(95% CI)

Adjusted RR

(95% CI)

Crude RR

(95% CI)

Adjusted RR

(95% CI)

Kilograms of Paraquat per Square Mile

  < 0.082

1.00

1.00

1.00

1.00

1.00

1.00

1.00

1.00

 0.082 to 0.321

0.99

(0.95-1.03)

0.99

(0.97-1.02)

1.02

(0.99-1.05)

1.01

(1.00-1.03)

1.02

(0.99-1.05)

1.02

(1.01-1.04)

1.03

(1.01-1.05)

1.03

(1.01-1.04)

 0.322 to 0.870

1.11

(1.07-1.15)

1.05

(1.02-1.08)

1.10

(1.07-1.12)

1.05

(1.04-1.07)

1.07

(1.05-1.10)

1.06

(1.05-1.08)

1.07

(1.05-1.09)

1.05

(1.04-1.07)

 0.871 to 2.282

1.09

(1.05-1.13)

1.06

(1.03-1.08)

1.10

(1.08-1.13)

1.08

(1.06-1.09)

1.10

(1.08-1.12)

1.09

(1.07-1.10)

1.09

(1.07-1.12)

1.07

(1.06-1.08)

  > 2.282

1.21

(1.17-1.26)

1.07

(1.04-1.10)

1.26

(1.23-1.30)

1.10

(1.09-1.12)

1.22

(1.19-1.25)

1.11

(1.09-1.12)

1.21

(1.19-1.24)

1.07

(1.06-1.09)

P for trend

< 0.001

< 0.0001

< 0.001

< 0.001

< 0.001

< 0.001

< 0.001

< 0.001

  1. aEstimated from a negative binomial regression with the natural log of the population as the model offset
  2. bAdjusted for age group (< 50, ≥ 50 years), race, sex, percent of the county population with a bachelor’s degree or higher, county-specific gross domestic product of the agricultural industry, and urban/rural classification