Association between outdoor air pollution and chronic rhinosinusitis patient reported outcomes

Table 2 Effect-modification observed for the spring–summer CRS population

Spring–Summer Population	BC		PM_2.5		NO₂		O₃
Spring–Summer Population	Estimate	p-value	Estimate	p-value	Estimate	p-value	Estimate	p-value
Sex (Male)	12.1	0.00495**	0.551	0.011*	0.539	0.0269*	0.0997	0.146
Age (+ 1 year)	-0,0353	0.820	0.00159	0.843	-0.00352	0.686	0.0101	2.18E-4***
CRSwNP	-6.41	0.206	-0.106	0.686	-0.540	0.0402*	0.00686	0.934
Comorbid AR	-2.63	0.55	0.177	0.145	-0.103	0.675	0.0651	0.376
Comorbid adulthood onset asthma	-1.65	0.760	0.544	0.0999	-0.425	0.141	0.344	3.65E-05***
Comorbid childhood onset asthma	1.20	0.801	0.146	0.550	0.0752	0.772	0.126	0.107
Comorbid COPD	13.0	0.0664	0.461	0.150	0.443	0.220	0.432	5.91E-06***
Smoker	-1.35	0.810	0.0174	0.946	-0.0791	0.807	0.156	0.0663
Prior Sinus Surgery	-12.4	0.00388**	-0.806	9.85E-04***	-0.690	0.0023**	0.129	0.0754

Effect modification displayed for the association between the total CRS symptom score covariates and a 1-unit (1 µg/m3) increment of the pollutants
^* p-value < 0.05
^** p-value < 0.01
^*** p-value < 0.001

ISSN: 1476-069X