Air pollution associated acute respiratory inflammation and modification by GSTM1 and GSTT1 gene polymorphisms: a panel study of healthy undergraduates

Zeng, Xiang; Tian, Ge; Zhu, Jingfang; Yang, Fuyun; Zhang, Rui; Li, Huijun; An, Zhen; Li, Juan; Song, Jie; Jiang, Jing; Liu, Dongling; Wu, Weidong

doi:10.1186/s12940-022-00954-9

Environmental Health

Table 3 Spearman correlation analyses of the relationship between air pollutants, inflammatory cytokines, and lung function

From: Air pollution associated acute respiratory inflammation and modification by GSTM1 and GSTT1 gene polymorphisms: a panel study of healthy undergraduates

	PM_2.5	PM₁₀	O₃	SO₂	NO₂	CO	T	RH	IL-6	IL-8	TNF-α	8-epi-PGF2α	FVC	FEV₁	FEV₁/FVC	PEF	FEF₂₅	FEF₇₅	MVV	MV
PM_2.5	—
PM₁₀	0.598	—
O₃	-0.234	-0.267	—
SO₂	0.134	0.232	-0.130	—
NO₂	0.488	0.515	-0.647	0.406	—
CO	0.479	0.403	-0.495	0.588	0.639	—
T	0.228	0.076	0.462	-0.136	-0.068	-0.345	—
RH	0.667	-0.344	-0.542	-0.054	0.453	0.535	-0.113	—
IL-6	-0.196	-0.008	-0.059	0.292	-0.101	0.306	-0.148	-0.300	—
IL-8	0.045	0.025	0.032	0.094	-0.137	0.046	0.031	-0.081	0.270	—
TNF-α	-0.345	-0.351	-0.293	-0.075	-0.427	-0.105	-0.422	-0.349	0.315	0.380	—
8-epi-PGF2α	-0.042	-0.037	0.020	0.075	-0.076	0.072	-0.019	-0.102	0.199	0.917	0.374	—
FVC	0.040	0.042	0.015	-0.013	0.063	-0.002	0.043	0.045	0.171	0.251	0.263	0.308	—
FEV₁	-0.028	0.047	-0.087	-0.004	0.089^#	0.040	-0.039	-0.031	0.201	0.285	0.251	0.307	0.852	—
FEV₁/FVC	-0.126	-0.001	-0.192	-0.013	0.064	0.056	-0.149	-0.127	0.043	-0.120	-0.073	-0.083	-0.359	0.075	—
PEF	-0.177	-0.008	-0.198	0.060	0.031	0.120	-0.191	-0.179	0.130	0.119	0.159	0.150	0.440	0.604	0.368	—
FEF₂₅	-0.405	-0.056	-0.429	0.097	0.078	0.248	-0.420	-0.401	0.168	0.062	0.162	0.127	0.429	0.629	0.426	0.972	—
FEF₇₅	0.386	0.113	0.336	-0.100	-0.003	-0.222	0.379	0.384	-0.030	0.022	-0.062	-0.032	0.054	0.408	0.765	0.456	0.506	—
MVV	-0.242	-0.037	-0.213	0.127	-0.035	0.174	-0.249	-0.204	0.210	0.150	0.264	0.149	0.653	0.722	0.050	0.600	0.593	0.328	—
MV	-0.140	-0.007	-0.096	0.102	0.004	0.129	-0.130	-0.128	0.233	0.041	0.062	0.031	0.224^#	0.238	0.016	0.181	0.174	0.039	0.262	—

Abbreviation: PM_2.5 fine particulate matter, PM₁₀ coarser particulate matter, O₃ ozone, SO₂ sulfur dioxide, NO₂ nitrogen dioxide, CO carbon monoxide, T temperature, RH relative humidity, Al aluminum, Ba barium, Sr strontium, V vanadium, Cr chromium, Mn manganese, Ni nickel, Cu copper, Zn zinc, Cd cadmium, Pd palladium, Ge germanium, As arsenic, B boron, Pb lead
The statistically significant correlations are highlighted in bold

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ISSN: 1476-069X

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