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Table 4 Estimated weights of different PFAS and Benchmark results for the corresponding exposure index. Analysis was restricted to antibody concentrations in Faroese individual data [15]. Indices were generated from the four serum-PFAS concentrations. Furthermore, weights were estimated using raw exposure concentrations (Raw) and after standardization (Stand.) of the concentrations. Benchmark results are for the age-5 serum weighted sum of PFAS serum concentrations (ng/mL)

From: Benchmark dose calculations for PFAS exposure based on two data sets on immunotoxic effects

  

Weights

 

BMR=5%

BMR=10%

Antibody

Method

PFOA

PFOS

PFHXS

PFNA

Model

BMD

BMDL

BMD

BMDL

Tetanus

Raw

0.739

0.059

0.163

0.040

linear

1.402

0.905

2.880

1.860

      

piecewise

1.232

0.515

2.532

1.059

 

Stand.

0.698

0.145

0.134

0.023

linear

1.761

1.115

3.618

2.290

      

piecewise

1.494

0.629

3.069

1.292

Diph.

Raw

0.570

0.208

0.125

0.096

linear

2.488

1.467

5.111

3.014

      

piecewise

1.336

0.667

2.745

1.370

 

Stand.

0.456

0.408

0.085

0.052

linear

3.896

2.249

8.003

4.619

      

piecewise

1.862

0.967

3.824

1.986