Table 2 OPs, VOCs – Blood/urine (Non routinely available)

Blood

VOCs

As soon as possible after event

If possible 6 and 12 h later and 1 month later^a

5 ml normal EDTA (2 ml transferred asap to coated headspace tubes)^b

Urine

OPs

As soon as possible after event

If possible, 6 and 12 h and 1 month later ^a

20 ml

What OPs, VOCs to look for:

 OPs

Tricresyl phosphate, meta, para, ortho isomers

Oil

trixylyl phosphates

Oil

tributyl phosphate

Hydraulic

triphenyl phosphate

Oil^c, Hydraulic

Others: dibutyl phenyl phosphate (DBPP); triisobutyl phosphate (TiBP); 2,6-di-tert-butyl-p-cresol (BHT)

Hydraulic

isopropylated phenyl, phosphate (3:1) (TIPP/PIP (3:1)

Hydraulic, Oil^c

 VOCs

Aldehydes, aliphatics, aromatics, ketones, alcohols and organics such as n-heptane, n-hexane, benzene, toluene, formaldehyde, acetaldehyde, n-pentane and n-octane. (Valeric acid / pentanoic acid, heptanoic acid, octanoic acid)

ASHRAE-Guideline 2021—Table 8–1 [55]

Table listing known OP metabolites

Substance

References

TmCP

dicresyl phosphate (DmCP)

Schindler et al. 2013 [100]

TpCP

dicresyl phosphate (DpCP);

p -hydroxybenzoic acid; di-p-cresyl phosphate (DCP); p-cresyl p-carboxyphenylphosphate (1coDCP)

Schindler et al. 2013 [100], Kurebayashi et al. 1985 [94]

ToCP^d

dicresyl phosphate (DoCP)

o-Cresyl dihydrogen phosphate and Di-o-Cresyl hydrogen phosphate, salicylic acid, o-hydroxybenzyl alcohol and o-cresol

Schindler et al. 2013 [100], Abou-donia et al. 1990 [104], Somkuti et al. 1990 [105]

TBP

DBP

Schindler et al. 2013 [100]

TPP

DPP

Schindler et al. 2013 [100]