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Table 3 Association between housing renovation exposure and isolated CHD in subgroups

From: Maternal exposure to housing renovation during the periconceptional period and the risk of offspring with isolated congenital heart disease: a case-control study

 

Subgroups

Model 1

 

Model 2 a

 

P for interaction

Crude OR (95%CI), P value

 

Adjusted OR (95%CI), P value

 

Maternal age

< 30 years

1.55 (1.17, 2.06), 0.003

 

1.66 (1.19, 2.33), 0.003

 

0.850

 

≥ 30 years

1.36 (0.89, 2.07), 0.150

 

2.04 (1.23, 3.36), 0.005

  

Education

High middle school and below

1.11 (0.72, 1.72), 0.639

 

1.61 (0.95, 2.72), 0.076

 

0.375

 

Above high middle school

1.85 (1.39, 2.46), < 0.001

 

2.01 (1.46, 2.76), < 0.001

  

Residence

Rural

1.83 (1.30, 2.59), < 0.001

 

2.01 (1.38, 2.92), < 0.001

 

0.598

 

Urban

1.49 (1.04, 2.13), 0.029

 

1.76 (1.17, 2.64), 0.006

  

Family wealth index

      
 

Low

1.07 (0.72, 1.57), 0.747

 

1.51 (0.94, 2.44), 0.088

 

0.074

 

Medium

1.86 (1.23, 2.82), 0.003

 

2.19 (1.39, 3.44), < 0.001

  
 

High

1.99 (1.25, 3.16), 0.004

 

2.27 (1.38, 3.75), 0.001

  

Parity

      
 

0

1.91 (1.47, 2.50), < 0.001

 

1.89 (1.41, 2.54), < 0.001

 

0.479

 

≥ 1

1.36 (0.75, 2.49), 0.314

 

1.62 (0.81, 3.26), 0.176

  

Abortion history

      
 

Yes

1.88 (1.25, 2.83), 0.002

 

2.16 (1.40, 3.45), 0.001

 

0.204

 

No

1.30 (0.97, 1.73), 0.077

 

1.68 (1.20, 2.35), 0.001

  
  1. a Model 2 adjusted maternal age, BMI, education, ethnicity, residence, family wealth index, parity, abortion history, family history of birth defects, active or passive smoke, drinking, folic acid supplement, fever, taking medicine, GDM, TORCH infections and industries exposure