Skip to main content

Table 5 Studies evaluating cigarette smoking as a determinant of maternal or neonatal PFAS concentrations by PFAS, study design, and findings

From: Determinants of maternal and neonatal PFAS concentrations: a review

PFAS (study design) a

N

Positive findings

N

Negative findings

N

Null findings

Legacy PFAS

 PFOA (C/L)

2

[78, 82]

1

[61]

5

[42, 62, 73, 76, 81]

 PFOA (C-S)

–

–

–

–

9

[64, 66, 67, 72, 83, 86, 87, 89, 93]

 PFOS (C/L)

1

[78]

2

[42, 82]

5

[61, 62, 73, 76, 81]

 PFOS (C-S)

1

[64]

4

[66, 67, 93, 94]

5

[72, 83, 86, 87, 89]

 PFNA (C/L)

1

[78]

–

–

5

[42, 73, 76, 81, 82]

 PFNA (C-S)

1

[87]

1

 

8

[64, 66, 67, 72, 83, 86, 89, 93]

 PFHxS (C/L)

3

[62, 73, 78]

–

–

5

[42, 61, 76, 81, 82]

 PFHxS (C-S)

–

–

1

[93]

7

[66, 72, 83, 86, 87, 89, 94]

Other PFAS

 Et-PFOSA-AcOH (C/L)

–

–

–

–

1

[78]

 Me-PFOSA-AcOH (C/L)

–

–

–

–

2

[42, 78]

 PFBS (C-S)

–

–

–

–

1

[86]

 PFDeA (C/L)

–

-

1

[73]

1

[82]

 PFDeA (C-S)

1

 

1

[93]

2

[77, 86]

 PFDoA (C/L)

–

–

1

[73]

1

[82]

 PFDoA (C-S)

1

[87]

–

–

1

[86]

 PFHpA (C/L)

–

–

–

–

1

[73]

 PFHpA (C-S)

1

[86]

–

–

–

–

 PFHpS (C-S)

–

–

1

[93]

–

–

 PFOSA (C-S)

–

–

–

–

1

[86]

 PFTrDA (C/L)

–

–

–

–

1

[82]

 PFTrDA (C-S)

1

[87]

–

–

–

–

 PFUnDA (C/L)

–

–

2

[73, 82]

–

–

 PFUnDA (C-S)

1

[87]

1

[93]

3

[64, 86, 89]

 ΣPFAS (C-S)

1

[87]

1

[93]

–

–

  1. a C/L Cohort/longitudinal studies, C-S Cross-sectional studies, PFOA Perfluorooctanoic acid, PFOS Perfluorooctane sulfonic acid, PFNA Perfluorononanoic acid, PFHxS Perfluorohexane sulfonate, Et-PFOSA-AcOH 2-(N-Ethyl-perfluorooctane sulfonamido) acetic acid, Me-PFOSA-AcOH 2-(N-Methyl-perfluorooctane sulfonamido) acetic acid, PFBS Perfluorobutane sulfonate, PFDeA Perfluorodecanoic acid, PFDoA Perfluorododecanoic acid, PFHpA Perfluoroheptanoic acid, PFHpS Perfluoroheptanesulfonic acid, PFOSA Perfluorooctanesulfonamide, PFTrDA Perfluorotridecanoic acid, PFUnDA Perfluoroundecanoic acid