Due to the complex interplay among different urban-related exposures, a comprehensive approach is advisable to estimate the health effects. We simultaneously assessed the effect of “green”, “grey” and air poll...
Authors: Giovanna Cilluffo, Giuliana Ferrante, Salvatore Fasola, Laura Montalbano, Velia Malizia, Alessandro Piscini, Vito Romaniello, Malvina Silvestri, Salvatore Stramondo, Massimo Stafoggia, Andrea Ranzi, Giovanni Viegi and Stefania La Grutta
Evidence suggests that childhood near-roadway air pollution (NRAP) exposures contribute to increased body mass index (BMI); however, effects of NRAP exposure during the vulnerable periods including in utero and f...
Authors: Jeniffer S. Kim, Tanya L. Alderete, Zhanghua Chen, Fred Lurmann, Ed Rappaport, Rima Habre, Kiros Berhane and Frank D. Gilliland
Environmental pollution exposure during pregnancy has been identified as a risk factor for preterm birth. Most studies have evaluated exposures individually and in limited study populations.
Authors: Amy M. Padula, Hongtai Huang, Rebecca J. Baer, Laura M. August, Marta M. Jankowska, Laura L. Jellife-Pawlowski, Marina Sirota and Tracey J. Woodruff
Numerous industries use organic solvents, and many workers from various occupational sectors are exposed to these known neurotoxicants, including pregnant women. Our objective is to explore whether occupationa...
Air pollution has been found to adversely affect children’s lung function. Forced expiratory volume in 1 s and forced vital capacity from spirometry have been studied most frequently, but measurements of airwa...
Authors: Isabelle Finke, Johan C. de Jongste, Henriette A. Smit, Alet H. Wijga, Gerard H. Koppelman, Judith Vonk, Bert Brunekreef and Ulrike Gehring
The purpose of this commentary is to consider whether the methods of the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) can provide accurate estimates of the impact of developmental neurotox...
Emerging evidence about the effects of endocrine disruptors on asthma symptoms suggests new opportunities to reduce asthma by changing personal environments. Right-to-know ethics supports returning personal re...
Authors: Laura J. Perovich, Jennifer Liss Ohayon, Elicia Mayuri Cousins, Rachel Morello-Frosch, Phil Brown, Gary Adamkiewicz and Julia Green Brody
Trichloramine exposure in indoor swimming pools has been suggested to cause asthma in children. We aimed to investigate the risk of asthma onset among children in relation to individual trichloramine exposure.
Authors: Martin Andersson, Helena Backman, Gunnar Nordberg, Annika Hagenbjörk, Linnea Hedman, Kåre Eriksson, Bertil Forsberg and Eva Rönmark
The age of menarche has been associated with metabolic and cardiovascular disease, as well as cancer risk. The decline in menarcheal age over the past century may be partially attributable to increased exposur...
Authors: Alexandra M. Binder, Camila Corvalan, Antonia M. Calafat, Xiaoyun Ye, Verónica Mericq, Ana Pereira and Karin B. Michels
Associations between ambient particulate matter < 2.5 μm (PM2.5) and asthma morbidity have been suggested in previous epidemiologic studies but results are inconsistent for areas with lower PM2.5 levels. We estim...
Authors: Roxana Khalili, Scott M. Bartell, Xuefei Hu, Yang Liu, Howard H. Chang, Candice Belanoff, Matthew J. Strickland and Verónica M. Vieira
Polychlorinated biphenyls (PCBs) are persistent organic environmental contaminants and known endocrine-disrupting chemicals (EDCs). Previous studies demonstrated that developmental exposure to the weakly estro...
Authors: Jan A. Mennigen, Lindsay M. Thompson, Mandee Bell, Marlen Tellez Santos and Andrea C. Gore
Prenatal exposure to persistent organic pollutants (POPs), may influence offspring weight gain. More prospective epidemiological studies are needed to compliment the growing body of evidence from animal studies.
Authors: Hilde B. Lauritzen, Tricia L. Larose, Torbjørn Øien, Torkjel M. Sandanger, Jon Ø. Odland, Margot van de Bor and Geir W. Jacobsen
Perfluoroalkyl and polyfluoroalkyl substances (PFASs) have been reported to suppress immune function. However, previous studies on prenatal exposure to PFASs and allergic disorders in offspring provided incons...
Authors: Qian Chen, Rong Huang, Li Hua, Yifeng Guo, Lisu Huang, Yanjun Zhao, Xia Wang and Jun Zhang
An increasing number of children are exposed to road traffic noise levels that may lead to adverse effects on health and daily functioning. Childhood is a period of intense growth and brain maturation, and chi...
Authors: Kjell Vegard Weyde, Norun Hjertager Krog, Bente Oftedal, Per Magnus, Simon Øverland, Stephen Stansfeld, Mark J. Nieuwenhuijsen, Martine Vrijheid, Montserrat de Castro Pascual and Gunn Marit Aasvang
The fractional concentration of exhaled nitric oxide (FeNO) is a biomarker of airway inflammation that has proved to be useful in investigations of genetic and epigenetic airway susceptibility to ambient air p...
Authors: Yue Zhang, Muhammad T. Salam, Kiros Berhane, Sandrah P. Eckel, Edward B. Rappaport, William S. Linn, Rima Habre, Theresa M. Bastain and Frank D. Gilliland
Previous studies suggest that periconceptional maternal occupational exposure to solvents and pesticides increase the risk of oral clefts in the offspring. Less is known about the effect of occupational exposu...
Authors: Nynke Spinder, Jorieke E. H. Bergman, H. Marike Boezen, Roel C. H. Vermeulen, Hans Kromhout and Hermien E. K. de Walle
Neurodevelopment is a complex process involving both genetic and environmental factors. Prenatal exposure to lead (Pb) has been associated with lower performance on neurodevelopmental tests. Adverse neurodevel...
Authors: Zhaoxi Wang, Birgit Claus Henn, Chaolong Wang, Yongyue Wei, Li Su, Ryan Sun, Han Chen, Peter J. Wagner, Quan Lu, Xihong Lin, Robert Wright, David Bellinger, Molly Kile, Maitreyi Mazumdar, Martha Maria Tellez-Rojo, Lourdes Schnaas…
Prenatal and postnatal exposure to bisphenol A (BPA) may affect early brain development. Rodent studies suggest that prenatal and postnatal neurodevelopmental toxicity from BPA exposure may manifest as social ...
Authors: Youn-Hee Lim, Sanghyuk Bae, Bung-Nyun Kim, Choong Ho Shin, Young Ah Lee, Johanna Inhyang Kim and Yun-Chul Hong
Phthalates and BPA are endocrine disrupting chemicals (EDCs) widely used in consumer products. Evidence suggests that phthalate and BPA exposure alters steroid hormone levels in adults, while in utero exposure...
Authors: Deborah J. Watkins, Brisa N. Sánchez, Martha Maria Téllez-Rojo, Joyce M. Lee, Adriana Mercado-García, Clara Blank-Goldenberg, Karen E. Peterson and John D. Meeker
Sex-specific factors play a major role in human health and disease, including responses to environmental stresses such as toxicant exposure. Increasing evidence suggests that such sex differences also exist du...
Authors: Emily F. Winterbottom, Devin C. Koestler, Dennis Liang Fei, Eric Wika, Anthony J. Capobianco, Carmen J. Marsit, Margaret R. Karagas and David J. Robbins
Health outcomes of electromagnetic fields (EMF) from mobile phones and their base stations are of concern. Conducting multidisciplinary research, targeting children and exploring dose-response are recommended....
Authors: Raika Durusoy, Hür Hassoy, Ahmet Özkurt and Ali Osman Karababa
In utero arsenic exposure may alter fetal developmental programming by altering DNA methylation, which may result in a higher risk of disease in later life. We evaluated the association between in utero arseni...
Authors: Akhilesh Kaushal, Hongmei Zhang, Wilfried J. J. Karmaus, Todd M. Everson, Carmen J. Marsit, Margaret R. Karagas, Shih-Fen Tsai, Hui-Ju Wen and Shu-Li Wang
Animal models show that prenatal bisphenol A (BPA) exposure leads to sexually dimorphic disruption of the neuroendocrine system in offspring, including the hypothalamic-pituitary-adrenal (HPA) neuroendocrine s...
Authors: Gerald F Giesbrecht, Maede Ejaredar, Jiaying Liu, Jenna Thomas, Nicole Letourneau, Tavis Campbell, Jonathan W Martin and Deborah Dewey
Prenatal exposure to organophosphate pesticides (OPs) has been associated with impaired child development. Pesticide exposure determinants need to be studied in order to identify sources and pathways of pestic...
Authors: Sabrina Llop, Mario Murcia, Carmen Iñiguez, Marta Roca, Llúcia González, Vicent Yusà, Marisa Rebagliato and Ferran Ballester
Ground-level ozone is a potent airway irritant and a determinant of respiratory morbidity. Susceptibility to the health effects of ambient ozone may be influenced by both intrinsic and extrinsic factors, such ...
Authors: Cassandra R. O’ Lenick, Howard H. Chang, Michael R. Kramer, Andrea Winquist, James A. Mulholland, Mariel D. Friberg and Stefanie Ebelt Sarnat
Children are exposed to flame retardants from the built environment. Brominated diphenyl ethers (BDE) and organophosphate-based flame retardants (OPFRs) are associated with poorer neurocognitive functioning in...
Authors: Shannon T. Lipscomb, Megan M. McClelland, Megan MacDonald, Andres Cardenas, Kim A. Anderson and Molly L. Kile
There are numerous examples of laboratory animals that were inadvertently exposed to endocrine disrupting chemicals (EDCs) during the process of conducting experiments. Controlling contaminations in the labora...
Authors: SriDurgaDevi Kolla, Aastha Pokharel and Laura N. Vandenberg
Despite increasing evidence on the relationship between exposure to phthalates and bisphenol A with allergies and asthma, reports on atopic dermatitis (AD) with these chemicals are few. We assessed the associa...
Authors: Eun-Hye Kim, Byoung-Hak Jeon, Jihyun Kim, Young-Min Kim, Youngshin Han, Kangmo Ahn and Hae-Kwan Cheong
There is a growing literature showing associations between prenatal and early-life exposure to air pollution and children’s neurodevelopment. However, it is unclear if decrements in neurodevelopment observed i...
Authors: Jeanette A. Stingone, Katharine H. McVeigh and Luz Claudio
The symposium entitled “Chernobyl +30, Fukushima +5: Lessons and Solutions for Fukushima’s Thyroid Question” was held in September, 2016 in Fukushima. The aim of the Symposium was to revisit and recapitulate e...
Authors: Vladimir A. Saenko, Geraldine A. Thomas and Shunichi Yamashita
The incidence of early childhood acute respiratory infections (ARIs) has been associated with aspects of the indoor environment. In recent years, public awareness about some of these environmental issues has i...
Authors: Sandar Tin Tin, Alistair Woodward, Rajneeta Saraf, Sarah Berry, Polly Atatoa Carr, Susan M. B. Morton and Cameron C. Grant
Lead toxicity is of particular public health concern given its near ubiquitous distribution in nature and established neurotoxicant properties. Similar in its ubiquity and ability to inhibit neurodevelopment, ...
Authors: Kelsey M. Gleason, Linda Valeri, A. H. Shankar, Md Omar Sharif Ibne Hasan, Quazi Quamruzzaman, Ema G. Rodrigues, David C. Christiani, Robert O. Wright, David C. Bellinger and Maitreyi Mazumdar
Most particulate matter (PM) and health studies in children with asthma use exposures averaged over the course of a day and do not take into account spatial/temporal variability that presumably occurs as child...
Authors: Nathan Rabinovitch, Colby D. Adams, Matthew Strand, Kirsten Koehler and John Volckens
Children with asthma experience increased susceptibility to airborne pollutants. Exposure to traffic and industrial activity have been positively associated with exacerbation of symptoms as well as emergency r...
Authors: Krystal J. Godri Pollitt, Caitlin L. Maikawa, Amanda J. Wheeler, Scott Weichenthal, Nina A. Dobbin, Ling Liu and Mark S. Goldberg
Children’s exposure to manganese (Mn) is a public health concern and consistent policy guidelines for safe levels of Mn exposure is lacking. The complexity of establishing exposure thresholds for Mn partially ...
Authors: Donna J. Coetzee, Patricia M. McGovern, Raghavendra Rao, Lisa J. Harnack, Michael K. Georgieff and Irina Stepanov
Phthalates, used in a variety of consumer products, are a group of chemicals that are ubiquitous in the environment, and their metabolites are detectable in most humans. Some phthalates have anti-androgenic pr...
Authors: Zana Percy, Yingying Xu, Heidi Sucharew, Jane C. Khoury, Antonia M. Calafat, Joseph M. Braun, Bruce P. Lanphear, Aimin Chen and Kimberly Yolton
Ultrafine particles (<100 nm) are ubiquitous present in the air and may contribute to adverse cardiovascular effects. Exposure to air pollutants can alter miRNA expression, which can affect downstream signalin...
Authors: Annette Vriens, Tim S. Nawrot, Nelly D. Saenen, Eline B. Provost, Michal Kicinski, Wouter Lefebvre, Charlotte Vanpoucke, Jan Van Deun, Olivier De Wever, Karen Vrijens, Patrick De Boever and Michelle Plusquin
Temperament is a psychological construct that reflects both personality and an infant’s reaction to social stimuli. It can be assessed early in life and is stable over time Temperament predicts many later life...
Authors: Annemarie Stroustrup, Hsiao-Hsien Hsu, Katherine Svensson, Lourdes Schnaas, Alejandra Cantoral, Maritsa Solano González, Mariana Torres-Calapiz, Chitra Amarasiriwardena, David C. Bellinger, Brent A. Coull, Martha M. Téllez-Rojo, Robert O. Wright and Rosalind J. Wright
Traffic exhaust, refineries and industrial facilities are major sources of air toxics identified by the U.S. Environmental Protection Agency (U.S. EPA) for their potential risk to human health. In utero and ea...
Authors: Elaine Symanski, P. Grace Tee Lewis, Ting-Yu Chen, Wenyaw Chan, Dejian Lai and Xiaomei Ma
In a community in northern Chile, explosive procedures are used by two local industrial mines (gold, copper). We hypothesized that the prevalence of asthma and rhinoconjunctivitis in the community may be assoc...
Authors: Ronald Herrera, Katja Radon, Ondine S. von Ehrenstein, Stella Cifuentes, Daniel Moraga Muñoz and Ursula Berger
Lead is a pervasive neurotoxicant that has been associated with poorer cognitive, behavioral, and motor outcomes in children. The effects of lead on sensory function have not been well characterized. The aim o...
Authors: Monica K. Silver, Xiaoqing Li, Yuhe Liu, Ming Li, Xiaoqin Mai, Niko Kaciroti, Paul Kileny, Twila Tardif, John D. Meeker and Betsy Lozoff
To investigate air pollution effects during pregnancy or in the first weeks of life, models are needed that capture both the spatial and temporal variability of air pollution exposures.
Authors: Elena Proietti, Edgar Delgado-Eckert, Danielle Vienneau, Georgette Stern, Ming-Yi Tsai, Philipp Latzin, Urs Frey and Martin Röösli
Household air pollution (HAP) - predominantly from cooking fuel is a major public health hazard and one of the leading causes of respiratory illness and deaths among children under-five years in India. This st...
Authors: Sabrina Naz, Andrew Page and Kingsley Emwinyore Agho
Polybrominated diphenyl ethers are known endocrine disrupting environmental contaminants used as flame retardants. Their levels have increased in humans over the last ten years, raising concerns about their co...
Authors: Yasmine K. Serme-Gbedo, Nadia Abdelouahab, Jean-Charles Pasquier, Alan A. Cohen and Larissa Takser
Bisphenol A (BPA) is a ubiquitous, endocrine-disrupting environmental contaminant that increases risk of some adverse developmental effects. Thus, it is important to characterize BPA levels, metabolic fate and...
Authors: Roy R. Gerona, Janet Pan, Ami R. Zota, Jackie M. Schwartz, Matthew Friesen, Julia A. Taylor, Patricia A. Hunt and Tracey J. Woodruff
The people of Bangladesh are currently exposed to high concentrations of arsenic and manganese in drinking water, as well as elevated lead in many regions. The objective of this study was to investigate associ...
Authors: Ema G. Rodrigues, David C. Bellinger, Linda Valeri, Md Omar Sharif Ibne Hasan, Quazi Quamruzzaman, Mostofa Golam, Molly L. Kile, David C. Christiani, Robert O. Wright and Maitreyi Mazumdar
Cortisol has functions on homeostasis, growth, neurodevelopment, immune function and the stress response. Secretion follows a diurnal rhythm that mediates these processes. Our objective was to examine the asso...
Authors: Marcela Tamayo y Ortiz, Martha María Téllez-Rojo, Rosalind J. Wright, Brent A. Coull and Robert O. Wright
Use of mobile (MP) and cordless phones (CP) is common among young children, but whether the resulting radiofrequency exposure affects development of cognitive skills is not known. Small changes have been found...
Authors: Mary Redmayne, Catherine L. Smith, Geza Benke, Rodney J. Croft, Anna Dalecki, Christina Dimitriadis, Jordy Kaufman, Skye Macleod, Malcolm R. Sim, Rory Wolfe and Michael J. Abramson
