Previous animal and ecological studies have provided evidence for an earlier sexual maturation in females in relation to fluoride exposure; however, no epidemiological studies have examined the association bet...
Authors: Yun Liu, Martha Téllez-Rojo, Howard Hu, Brisa N. Sánchez, E. Angeles Martinez-Mier, Niladri Basu, Adriana Mercado-García, Maritsa Solano-González and Karen E. Peterson
Despite evidence of the endocrine disrupting properties of zearalenone (ZEN) and alpha-zearalanol (zeranol, α-ZAL), they have been minimally studied in human populations. In previous cross-sectional analyses, ...
Authors: Zorimar Rivera-Núñez, Emily S. Barrett, Elizabeth A. Szamreta, Sue A. Shapses, Bo Qin, Yong Lin, Helmut Zarbl, Brian Buckley and Elisa V. Bandera
The association between exposure to secondhand smoke (SHS) during pregnancy and a child’s neurodevelopment has not been established yet. We explored the association between prenatal exposure to SHS and neurode...
Authors: Myeongjee Lee, Mina Ha, Yun-Chul Hong, Hyesook Park, Yangho Kim, Eui-Jung Kim, Yeni Kim and Eunhee Ha
Prenatal exposure to arsenic has been linked to a range of adverse health conditions in later life. Such fetal origins of disease are frequently the result of environmental effects on the epigenome, leading to...
Authors: Emily F. Winterbottom, Yuka Moroishi, Yuliya Halchenko, David A. Armstrong, Paul J. Beach, Quang P. Nguyen, Anthony J. Capobianco, Nagi G. Ayad, Carmen J. Marsit, Zhigang Li, Margaret R. Karagas and David J. Robbins
Child neurodevelopment has been positively linked to maternal intake of polyunsaturated fatty acids (PUFAs) during pregnancy; however, it is unknown if that relationship persists among populations exposed to e...
Authors: Ángel Mérida-Ortega, Stephen J. Rothenberg, Luisa Torres-Sánchez, Lourdes Schnaas, César Hernández-Alcaraz, Mariano E. Cebrián, Rosa María García-Hernández, Rafael Ogaz-González and Lizbeth López-Carrillo
The purpose of this article is to consider alternate uses of the blood lead reference value for children. There are two possible approaches. Historically the reference value has been used to guide clinical and...
Studies on the effect of prenatal exposure to magnetic field (MF) on fetal growth is inconclusive and subject to some methodological limitations, particularly in measurement of MF exposure. The present study a...
Authors: Yanfeng Ren, Jianping Chen, Maohua Miao, De-Kun Li, Hong Liang, Ziliang Wang, Fen Yang, Xiaowei Sun and Wei Yuan
Mercury is toxic to the developing brain, but the lowest concentration associated with the development of behavior problems is unclear. The purpose of this study was to examine the association between very low...
Authors: Nimesh B. Patel, Yingying Xu, Lawrence C. McCandless, Aimin Chen, Kimberly Yolton, Joseph Braun, Robert L. Jones, Kim N. Dietrich and Bruce P. Lanphear
Numerous studies have examined the association between air pollution and preterm birth (< 37 weeks gestation) but findings have been inconsistent. These associations may be more difficult to detect than associ...
Authors: David M. Stieb, Eric Lavigne, Li Chen, Lauren Pinault, Antonio Gasparrini and Michael Tjepkema
Naphthalene is the simplest polycyclic aromatic hydrocarbon (PAH). It is easily emitted into the atmosphere, posing a significant risk to human health. However, limited studies have described the impact of nap...
Authors: Jisheng Nie, Jinyu Li, Lin Cheng, Yanning Li, Yunjun Deng, Zhiwei Yan, Lei Duan, Qiao Niu, Frederica Perera and Deliang Tang
Due to the complex interplay among different urban-related exposures, a comprehensive approach is advisable to estimate the health effects. We simultaneously assessed the effect of “green”, “grey” and air poll...
Authors: Giovanna Cilluffo, Giuliana Ferrante, Salvatore Fasola, Laura Montalbano, Velia Malizia, Alessandro Piscini, Vito Romaniello, Malvina Silvestri, Salvatore Stramondo, Massimo Stafoggia, Andrea Ranzi, Giovanni Viegi and Stefania La Grutta
Evidence suggests that childhood near-roadway air pollution (NRAP) exposures contribute to increased body mass index (BMI); however, effects of NRAP exposure during the vulnerable periods including in utero and f...
Authors: Jeniffer S. Kim, Tanya L. Alderete, Zhanghua Chen, Fred Lurmann, Ed Rappaport, Rima Habre, Kiros Berhane and Frank D. Gilliland
Environmental pollution exposure during pregnancy has been identified as a risk factor for preterm birth. Most studies have evaluated exposures individually and in limited study populations.
Authors: Amy M. Padula, Hongtai Huang, Rebecca J. Baer, Laura M. August, Marta M. Jankowska, Laura L. Jellife-Pawlowski, Marina Sirota and Tracey J. Woodruff
Numerous industries use organic solvents, and many workers from various occupational sectors are exposed to these known neurotoxicants, including pregnant women. Our objective is to explore whether occupationa...
Air pollution has been found to adversely affect children’s lung function. Forced expiratory volume in 1 s and forced vital capacity from spirometry have been studied most frequently, but measurements of airwa...
Authors: Isabelle Finke, Johan C. de Jongste, Henriette A. Smit, Alet H. Wijga, Gerard H. Koppelman, Judith Vonk, Bert Brunekreef and Ulrike Gehring
The purpose of this commentary is to consider whether the methods of the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) can provide accurate estimates of the impact of developmental neurotox...
Emerging evidence about the effects of endocrine disruptors on asthma symptoms suggests new opportunities to reduce asthma by changing personal environments. Right-to-know ethics supports returning personal re...
Authors: Laura J. Perovich, Jennifer Liss Ohayon, Elicia Mayuri Cousins, Rachel Morello-Frosch, Phil Brown, Gary Adamkiewicz and Julia Green Brody
Trichloramine exposure in indoor swimming pools has been suggested to cause asthma in children. We aimed to investigate the risk of asthma onset among children in relation to individual trichloramine exposure.
Authors: Martin Andersson, Helena Backman, Gunnar Nordberg, Annika Hagenbjörk, Linnea Hedman, Kåre Eriksson, Bertil Forsberg and Eva Rönmark
The age of menarche has been associated with metabolic and cardiovascular disease, as well as cancer risk. The decline in menarcheal age over the past century may be partially attributable to increased exposur...
Authors: Alexandra M. Binder, Camila Corvalan, Antonia M. Calafat, Xiaoyun Ye, Verónica Mericq, Ana Pereira and Karin B. Michels
Associations between ambient particulate matter < 2.5 μm (PM2.5) and asthma morbidity have been suggested in previous epidemiologic studies but results are inconsistent for areas with lower PM2.5 levels. We estim...
Authors: Roxana Khalili, Scott M. Bartell, Xuefei Hu, Yang Liu, Howard H. Chang, Candice Belanoff, Matthew J. Strickland and Verónica M. Vieira
Polychlorinated biphenyls (PCBs) are persistent organic environmental contaminants and known endocrine-disrupting chemicals (EDCs). Previous studies demonstrated that developmental exposure to the weakly estro...
Authors: Jan A. Mennigen, Lindsay M. Thompson, Mandee Bell, Marlen Tellez Santos and Andrea C. Gore
Prenatal exposure to persistent organic pollutants (POPs), may influence offspring weight gain. More prospective epidemiological studies are needed to compliment the growing body of evidence from animal studies.
Authors: Hilde B. Lauritzen, Tricia L. Larose, Torbjørn Øien, Torkjel M. Sandanger, Jon Ø. Odland, Margot van de Bor and Geir W. Jacobsen
Perfluoroalkyl and polyfluoroalkyl substances (PFASs) have been reported to suppress immune function. However, previous studies on prenatal exposure to PFASs and allergic disorders in offspring provided incons...
Authors: Qian Chen, Rong Huang, Li Hua, Yifeng Guo, Lisu Huang, Yanjun Zhao, Xia Wang and Jun Zhang
An increasing number of children are exposed to road traffic noise levels that may lead to adverse effects on health and daily functioning. Childhood is a period of intense growth and brain maturation, and chi...
Authors: Kjell Vegard Weyde, Norun Hjertager Krog, Bente Oftedal, Per Magnus, Simon Øverland, Stephen Stansfeld, Mark J. Nieuwenhuijsen, Martine Vrijheid, Montserrat de Castro Pascual and Gunn Marit Aasvang
The fractional concentration of exhaled nitric oxide (FeNO) is a biomarker of airway inflammation that has proved to be useful in investigations of genetic and epigenetic airway susceptibility to ambient air p...
Authors: Yue Zhang, Muhammad T. Salam, Kiros Berhane, Sandrah P. Eckel, Edward B. Rappaport, William S. Linn, Rima Habre, Theresa M. Bastain and Frank D. Gilliland
Previous studies suggest that periconceptional maternal occupational exposure to solvents and pesticides increase the risk of oral clefts in the offspring. Less is known about the effect of occupational exposu...
Authors: Nynke Spinder, Jorieke E. H. Bergman, H. Marike Boezen, Roel C. H. Vermeulen, Hans Kromhout and Hermien E. K. de Walle
Neurodevelopment is a complex process involving both genetic and environmental factors. Prenatal exposure to lead (Pb) has been associated with lower performance on neurodevelopmental tests. Adverse neurodevel...
Authors: Zhaoxi Wang, Birgit Claus Henn, Chaolong Wang, Yongyue Wei, Li Su, Ryan Sun, Han Chen, Peter J. Wagner, Quan Lu, Xihong Lin, Robert Wright, David Bellinger, Molly Kile, Maitreyi Mazumdar, Martha Maria Tellez-Rojo, Lourdes Schnaas…
Prenatal and postnatal exposure to bisphenol A (BPA) may affect early brain development. Rodent studies suggest that prenatal and postnatal neurodevelopmental toxicity from BPA exposure may manifest as social ...
Authors: Youn-Hee Lim, Sanghyuk Bae, Bung-Nyun Kim, Choong Ho Shin, Young Ah Lee, Johanna Inhyang Kim and Yun-Chul Hong
Phthalates and BPA are endocrine disrupting chemicals (EDCs) widely used in consumer products. Evidence suggests that phthalate and BPA exposure alters steroid hormone levels in adults, while in utero exposure...
Authors: Deborah J. Watkins, Brisa N. Sánchez, Martha Maria Téllez-Rojo, Joyce M. Lee, Adriana Mercado-García, Clara Blank-Goldenberg, Karen E. Peterson and John D. Meeker
Sex-specific factors play a major role in human health and disease, including responses to environmental stresses such as toxicant exposure. Increasing evidence suggests that such sex differences also exist du...
Authors: Emily F. Winterbottom, Devin C. Koestler, Dennis Liang Fei, Eric Wika, Anthony J. Capobianco, Carmen J. Marsit, Margaret R. Karagas and David J. Robbins
Health outcomes of electromagnetic fields (EMF) from mobile phones and their base stations are of concern. Conducting multidisciplinary research, targeting children and exploring dose-response are recommended....
Authors: Raika Durusoy, Hür Hassoy, Ahmet Özkurt and Ali Osman Karababa
In utero arsenic exposure may alter fetal developmental programming by altering DNA methylation, which may result in a higher risk of disease in later life. We evaluated the association between in utero arseni...
Authors: Akhilesh Kaushal, Hongmei Zhang, Wilfried J. J. Karmaus, Todd M. Everson, Carmen J. Marsit, Margaret R. Karagas, Shih-Fen Tsai, Hui-Ju Wen and Shu-Li Wang
Animal models show that prenatal bisphenol A (BPA) exposure leads to sexually dimorphic disruption of the neuroendocrine system in offspring, including the hypothalamic-pituitary-adrenal (HPA) neuroendocrine s...
Authors: Gerald F Giesbrecht, Maede Ejaredar, Jiaying Liu, Jenna Thomas, Nicole Letourneau, Tavis Campbell, Jonathan W Martin and Deborah Dewey
Prenatal exposure to organophosphate pesticides (OPs) has been associated with impaired child development. Pesticide exposure determinants need to be studied in order to identify sources and pathways of pestic...
Authors: Sabrina Llop, Mario Murcia, Carmen Iñiguez, Marta Roca, Llúcia González, Vicent Yusà, Marisa Rebagliato and Ferran Ballester
Ground-level ozone is a potent airway irritant and a determinant of respiratory morbidity. Susceptibility to the health effects of ambient ozone may be influenced by both intrinsic and extrinsic factors, such ...
Authors: Cassandra R. O’ Lenick, Howard H. Chang, Michael R. Kramer, Andrea Winquist, James A. Mulholland, Mariel D. Friberg and Stefanie Ebelt Sarnat
There are numerous examples of laboratory animals that were inadvertently exposed to endocrine disrupting chemicals (EDCs) during the process of conducting experiments. Controlling contaminations in the labora...
Authors: SriDurgaDevi Kolla, Aastha Pokharel and Laura N. Vandenberg
Despite increasing evidence on the relationship between exposure to phthalates and bisphenol A with allergies and asthma, reports on atopic dermatitis (AD) with these chemicals are few. We assessed the associa...
Authors: Eun-Hye Kim, Byoung-Hak Jeon, Jihyun Kim, Young-Min Kim, Youngshin Han, Kangmo Ahn and Hae-Kwan Cheong
Children are exposed to flame retardants from the built environment. Brominated diphenyl ethers (BDE) and organophosphate-based flame retardants (OPFRs) are associated with poorer neurocognitive functioning in...
Authors: Shannon T. Lipscomb, Megan M. McClelland, Megan MacDonald, Andres Cardenas, Kim A. Anderson and Molly L. Kile
The symposium entitled “Chernobyl +30, Fukushima +5: Lessons and Solutions for Fukushima’s Thyroid Question” was held in September, 2016 in Fukushima. The aim of the Symposium was to revisit and recapitulate e...
Authors: Vladimir A. Saenko, Geraldine A. Thomas and Shunichi Yamashita
There is a growing literature showing associations between prenatal and early-life exposure to air pollution and children’s neurodevelopment. However, it is unclear if decrements in neurodevelopment observed i...
Authors: Jeanette A. Stingone, Katharine H. McVeigh and Luz Claudio
The incidence of early childhood acute respiratory infections (ARIs) has been associated with aspects of the indoor environment. In recent years, public awareness about some of these environmental issues has i...
Authors: Sandar Tin Tin, Alistair Woodward, Rajneeta Saraf, Sarah Berry, Polly Atatoa Carr, Susan M. B. Morton and Cameron C. Grant
Lead toxicity is of particular public health concern given its near ubiquitous distribution in nature and established neurotoxicant properties. Similar in its ubiquity and ability to inhibit neurodevelopment, ...
Authors: Kelsey M. Gleason, Linda Valeri, A. H. Shankar, Md Omar Sharif Ibne Hasan, Quazi Quamruzzaman, Ema G. Rodrigues, David C. Christiani, Robert O. Wright, David C. Bellinger and Maitreyi Mazumdar
Most particulate matter (PM) and health studies in children with asthma use exposures averaged over the course of a day and do not take into account spatial/temporal variability that presumably occurs as child...
Authors: Nathan Rabinovitch, Colby D. Adams, Matthew Strand, Kirsten Koehler and John Volckens
Children with asthma experience increased susceptibility to airborne pollutants. Exposure to traffic and industrial activity have been positively associated with exacerbation of symptoms as well as emergency r...
Authors: Krystal J. Godri Pollitt, Caitlin L. Maikawa, Amanda J. Wheeler, Scott Weichenthal, Nina A. Dobbin, Ling Liu and Mark S. Goldberg
Children’s exposure to manganese (Mn) is a public health concern and consistent policy guidelines for safe levels of Mn exposure is lacking. The complexity of establishing exposure thresholds for Mn partially ...
Authors: Donna J. Coetzee, Patricia M. McGovern, Raghavendra Rao, Lisa J. Harnack, Michael K. Georgieff and Irina Stepanov
Phthalates, used in a variety of consumer products, are a group of chemicals that are ubiquitous in the environment, and their metabolites are detectable in most humans. Some phthalates have anti-androgenic pr...
Authors: Zana Percy, Yingying Xu, Heidi Sucharew, Jane C. Khoury, Antonia M. Calafat, Joseph M. Braun, Bruce P. Lanphear, Aimin Chen and Kimberly Yolton
