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Children’s Environmental Health

Health effects of early-life exposures to environmental hazards

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  1. The age of menarche has been associated with metabolic and cardiovascular disease, as well as cancer risk. The decline in menarcheal age over the past century may be partially attributable to increased exposur...

    Authors: Alexandra M. Binder, Camila Corvalan, Antonia M. Calafat, Xiaoyun Ye, Verónica Mericq, Ana Pereira and Karin B. Michels

    Citation: Environmental Health 2018 17:32

    Content type: Research

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  2. Associations between ambient particulate matter < 2.5 μm (PM2.5) and asthma morbidity have been suggested in previous epidemiologic studies but results are inconsistent for areas with lower PM2.5 levels. We estim...

    Authors: Roxana Khalili, Scott M. Bartell, Xuefei Hu, Yang Liu, Howard H. Chang, Candice Belanoff, Matthew J. Strickland and Verónica M. Vieira

    Citation: Environmental Health 2018 17:20

    Content type: Research

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    The Correction to this article has been published in Environmental Health 2018 17:25

  3. Polychlorinated biphenyls (PCBs) are persistent organic environmental contaminants and known endocrine-disrupting chemicals (EDCs). Previous studies demonstrated that developmental exposure to the weakly estro...

    Authors: Jan A. Mennigen, Lindsay M. Thompson, Mandee Bell, Marlen Tellez Santos and Andrea C. Gore

    Citation: Environmental Health 2018 17:18

    Content type: Research

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  4. Prenatal exposure to persistent organic pollutants (POPs), may influence offspring weight gain. More prospective epidemiological studies are needed to compliment the growing body of evidence from animal studies.

    Authors: Hilde B. Lauritzen, Tricia L. Larose, Torbjørn Øien, Torkjel M. Sandanger, Jon Ø. Odland, Margot van de Bor and Geir W. Jacobsen

    Citation: Environmental Health 2018 17:9

    Content type: Research

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  5. Perfluoroalkyl and polyfluoroalkyl substances (PFASs) have been reported to suppress immune function. However, previous studies on prenatal exposure to PFASs and allergic disorders in offspring provided incons...

    Authors: Qian Chen, Rong Huang, Li Hua, Yifeng Guo, Lisu Huang, Yanjun Zhao, Xia Wang and Jun Zhang

    Citation: Environmental Health 2018 17:8

    Content type: Research

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  6. An increasing number of children are exposed to road traffic noise levels that may lead to adverse effects on health and daily functioning. Childhood is a period of intense growth and brain maturation, and chi...

    Authors: Kjell Vegard Weyde, Norun Hjertager Krog, Bente Oftedal, Per Magnus, Simon Øverland, Stephen Stansfeld, Mark J. Nieuwenhuijsen, Martine Vrijheid, Montserrat de Castro Pascual and Gunn Marit Aasvang

    Citation: Environmental Health 2017 16:127

    Content type: Research

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  7. The fractional concentration of exhaled nitric oxide (FeNO) is a biomarker of airway inflammation that has proved to be useful in investigations of genetic and epigenetic airway susceptibility to ambient air p...

    Authors: Yue Zhang, Muhammad T. Salam, Kiros Berhane, Sandrah P. Eckel, Edward B. Rappaport, William S. Linn, Rima Habre, Theresa M. Bastain and Frank D. Gilliland

    Citation: Environmental Health 2017 16:88

    Content type: Research

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  8. Previous studies suggest that periconceptional maternal occupational exposure to solvents and pesticides increase the risk of oral clefts in the offspring. Less is known about the effect of occupational exposu...

    Authors: Nynke Spinder, Jorieke E. H. Bergman, H. Marike Boezen, Roel C. H. Vermeulen, Hans Kromhout and Hermien E. K. de Walle

    Citation: Environmental Health 2017 16:83

    Content type: Research

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  9. Neurodevelopment is a complex process involving both genetic and environmental factors. Prenatal exposure to lead (Pb) has been associated with lower performance on neurodevelopmental tests. Adverse neurodevel...

    Authors: Zhaoxi Wang, Birgit Claus Henn, Chaolong Wang, Yongyue Wei, Li Su, Ryan Sun, Han Chen, Peter J. Wagner, Quan Lu, Xihong Lin, Robert Wright, David Bellinger, Molly Kile, Maitreyi Mazumdar, Martha Maria Tellez-Rojo, Lourdes Schnaas…

    Citation: Environmental Health 2017 16:81

    Content type: Research

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  11. Prenatal and postnatal exposure to bisphenol A (BPA) may affect early brain development. Rodent studies suggest that prenatal and postnatal neurodevelopmental toxicity from BPA exposure may manifest as social ...

    Authors: Youn-Hee Lim, Sanghyuk Bae, Bung-Nyun Kim, Choong Ho Shin, Young Ah Lee, Johanna Inhyang Kim and Yun-Chul Hong

    Citation: Environmental Health 2017 16:79

    Content type: Research

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  12. Phthalates and BPA are endocrine disrupting chemicals (EDCs) widely used in consumer products. Evidence suggests that phthalate and BPA exposure alters steroid hormone levels in adults, while in utero exposure...

    Authors: Deborah J. Watkins, Brisa N. Sánchez, Martha Maria Téllez-Rojo, Joyce M. Lee, Adriana Mercado-García, Clara Blank-Goldenberg, Karen E. Peterson and John D. Meeker

    Citation: Environmental Health 2017 16:69

    Content type: Research

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  13. Sex-specific factors play a major role in human health and disease, including responses to environmental stresses such as toxicant exposure. Increasing evidence suggests that such sex differences also exist du...

    Authors: Emily F. Winterbottom, Devin C. Koestler, Dennis Liang Fei, Eric Wika, Anthony J. Capobianco, Carmen J. Marsit, Margaret R. Karagas and David J. Robbins

    Citation: Environmental Health 2017 16:59

    Content type: Research

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  14. Health outcomes of electromagnetic fields (EMF) from mobile phones and their base stations are of concern. Conducting multidisciplinary research, targeting children and exploring dose-response are recommended....

    Authors: Raika Durusoy, Hür Hassoy, Ahmet Özkurt and Ali Osman Karababa

    Citation: Environmental Health 2017 16:51

    Content type: Research

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  15. In utero arsenic exposure may alter fetal developmental programming by altering DNA methylation, which may result in a higher risk of disease in later life. We evaluated the association between in utero arseni...

    Authors: Akhilesh Kaushal, Hongmei Zhang, Wilfried J. J. Karmaus, Todd M. Everson, Carmen J. Marsit, Margaret R. Karagas, Shih-Fen Tsai, Hui-Ju Wen and Shu-Li Wang

    Citation: Environmental Health 2017 16:50

    Content type: Research

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  16. Animal models show that prenatal bisphenol A (BPA) exposure leads to sexually dimorphic disruption of the neuroendocrine system in offspring, including the hypothalamic-pituitary-adrenal (HPA) neuroendocrine s...

    Authors: Gerald F Giesbrecht, Maede Ejaredar, Jiaying Liu, Jenna Thomas, Nicole Letourneau, Tavis Campbell, Jonathan W Martin and Deborah Dewey

    Citation: Environmental Health 2017 16:47

    Content type: Research

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  17. Prenatal exposure to organophosphate pesticides (OPs) has been associated with impaired child development. Pesticide exposure determinants need to be studied in order to identify sources and pathways of pestic...

    Authors: Sabrina Llop, Mario Murcia, Carmen Iñiguez, Marta Roca, Llúcia González, Vicent Yusà, Marisa Rebagliato and Ferran Ballester

    Citation: Environmental Health 2017 16:46

    Content type: Research

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  18. Ground-level ozone is a potent airway irritant and a determinant of respiratory morbidity. Susceptibility to the health effects of ambient ozone may be influenced by both intrinsic and extrinsic factors, such ...

    Authors: Cassandra R. O’ Lenick, Howard H. Chang, Michael R. Kramer, Andrea Winquist, James A. Mulholland, Mariel D. Friberg and Stefanie Ebelt Sarnat

    Citation: Environmental Health 2017 16:36

    Content type: Research

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    The Erratum to this article has been published in Environmental Health 2017 16:63

  19. There are numerous examples of laboratory animals that were inadvertently exposed to endocrine disrupting chemicals (EDCs) during the process of conducting experiments. Controlling contaminations in the labora...

    Authors: SriDurgaDevi Kolla, Aastha Pokharel and Laura N. Vandenberg

    Citation: Environmental Health 2017 16:25

    Content type: Research

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  20. Despite increasing evidence on the relationship between exposure to phthalates and bisphenol A with allergies and asthma, reports on atopic dermatitis (AD) with these chemicals are few. We assessed the associa...

    Authors: Eun-Hye Kim, Byoung-Hak Jeon, Jihyun Kim, Young-Min Kim, Youngshin Han, Kangmo Ahn and Hae-Kwan Cheong

    Citation: Environmental Health 2017 16:24

    Content type: Research

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  21. Children are exposed to flame retardants from the built environment. Brominated diphenyl ethers (BDE) and organophosphate-based flame retardants (OPFRs) are associated with poorer neurocognitive functioning in...

    Authors: Shannon T. Lipscomb, Megan M. McClelland, Megan MacDonald, Andres Cardenas, Kim A. Anderson and Molly L. Kile

    Citation: Environmental Health 2017 16:23

    Content type: Research

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  22. The symposium entitled “Chernobyl +30, Fukushima +5: Lessons and Solutions for Fukushima’s Thyroid Question” was held in September, 2016 in Fukushima. The aim of the Symposium was to revisit and recapitulate e...

    Authors: Vladimir A. Saenko, Geraldine A. Thomas and Shunichi Yamashita

    Citation: Environmental Health 2017 16:3

    Content type: Commentary

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  23. There is a growing literature showing associations between prenatal and early-life exposure to air pollution and children’s neurodevelopment. However, it is unclear if decrements in neurodevelopment observed i...

    Authors: Jeanette A. Stingone, Katharine H. McVeigh and Luz Claudio

    Citation: Environmental Health 2017 16:2

    Content type: Research

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  24. The incidence of early childhood acute respiratory infections (ARIs) has been associated with aspects of the indoor environment. In recent years, public awareness about some of these environmental issues has i...

    Authors: Sandar Tin Tin, Alistair Woodward, Rajneeta Saraf, Sarah Berry, Polly Atatoa Carr, Susan M. B. Morton and Cameron C. Grant

    Citation: Environmental Health 2016 15:120

    Content type: Research

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  25. Estimating the health effects of ambient air pollutant mixtures is necessary to understand the risk of real-life air pollution exposures.

    Authors: Qingyang Xiao, Yang Liu, James A. Mulholland, Armistead G. Russell, Lyndsey A. Darrow, Paige E. Tolbert and Matthew J. Strickland

    Citation: Environmental Health 2016 15:115

    Content type: Research

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  26. Lead toxicity is of particular public health concern given its near ubiquitous distribution in nature and established neurotoxicant properties. Similar in its ubiquity and ability to inhibit neurodevelopment, ...

    Authors: Kelsey M. Gleason, Linda Valeri, A. H. Shankar, Md Omar Sharif Ibne Hasan, Quazi Quamruzzaman, Ema G. Rodrigues, David C. Christiani, Robert O. Wright, David C. Bellinger and Maitreyi Mazumdar

    Citation: Environmental Health 2016 15:103

    Content type: Research

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  27. Most particulate matter (PM) and health studies in children with asthma use exposures averaged over the course of a day and do not take into account spatial/temporal variability that presumably occurs as child...

    Authors: Nathan Rabinovitch, Colby D. Adams, Matthew Strand, Kirsten Koehler and John Volckens

    Citation: Environmental Health 2016 15:96

    Content type: Research

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  28. Children with asthma experience increased susceptibility to airborne pollutants. Exposure to traffic and industrial activity have been positively associated with exacerbation of symptoms as well as emergency r...

    Authors: Krystal J. Godri Pollitt, Caitlin L. Maikawa, Amanda J. Wheeler, Scott Weichenthal, Nina A. Dobbin, Ling Liu and Mark S. Goldberg

    Citation: Environmental Health 2016 15:94

    Content type: Research

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  29. Children’s exposure to manganese (Mn) is a public health concern and consistent policy guidelines for safe levels of Mn exposure is lacking. The complexity of establishing exposure thresholds for Mn partially ...

    Authors: Donna J. Coetzee, Patricia M. McGovern, Raghavendra Rao, Lisa J. Harnack, Michael K. Georgieff and Irina Stepanov

    Citation: Environmental Health 2016 15:91

    Content type: Review

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  30. Phthalates, used in a variety of consumer products, are a group of chemicals that are ubiquitous in the environment, and their metabolites are detectable in most humans. Some phthalates have anti-androgenic pr...

    Authors: Zana Percy, Yingying Xu, Heidi Sucharew, Jane C. Khoury, Antonia M. Calafat, Joseph M. Braun, Bruce P. Lanphear, Aimin Chen and Kimberly Yolton

    Citation: Environmental Health 2016 15:87

    Content type: Research

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  31. Ultrafine particles (<100 nm) are ubiquitous present in the air and may contribute to adverse cardiovascular effects. Exposure to air pollutants can alter miRNA expression, which can affect downstream signalin...

    Authors: Annette Vriens, Tim S. Nawrot, Nelly D. Saenen, Eline B. Provost, Michal Kicinski, Wouter Lefebvre, Charlotte Vanpoucke, Jan Van Deun, Olivier De Wever, Karen Vrijens, Patrick De Boever and Michelle Plusquin

    Citation: Environmental Health 2016 15:80

    Content type: Research

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  32. Temperament is a psychological construct that reflects both personality and an infant’s reaction to social stimuli. It can be assessed early in life and is stable over time Temperament predicts many later life...

    Authors: Annemarie Stroustrup, Hsiao-Hsien Hsu, Katherine Svensson, Lourdes Schnaas, Alejandra Cantoral, Maritsa Solano González, Mariana Torres-Calapiz, Chitra Amarasiriwardena, David C. Bellinger, Brent A. Coull, Martha M. Téllez-Rojo, Robert O. Wright and Rosalind J. Wright

    Citation: Environmental Health 2016 15:71

    Content type: Research

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  33. Traffic exhaust, refineries and industrial facilities are major sources of air toxics identified by the U.S. Environmental Protection Agency (U.S. EPA) for their potential risk to human health. In utero and ea...

    Authors: Elaine Symanski, P. Grace Tee Lewis, Ting-Yu Chen, Wenyaw Chan, Dejian Lai and Xiaomei Ma

    Citation: Environmental Health 2016 15:70

    Content type: Research

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  34. In a community in northern Chile, explosive procedures are used by two local industrial mines (gold, copper). We hypothesized that the prevalence of asthma and rhinoconjunctivitis in the community may be assoc...

    Authors: Ronald Herrera, Katja Radon, Ondine S. von Ehrenstein, Stella Cifuentes, Daniel Moraga Muñoz and Ursula Berger

    Citation: Environmental Health 2016 15:66

    Content type: Research

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  35. Lead is a pervasive neurotoxicant that has been associated with poorer cognitive, behavioral, and motor outcomes in children. The effects of lead on sensory function have not been well characterized. The aim o...

    Authors: Monica K. Silver, Xiaoqing Li, Yuhe Liu, Ming Li, Xiaoqin Mai, Niko Kaciroti, Paul Kileny, Twila Tardif, John D. Meeker and Betsy Lozoff

    Citation: Environmental Health 2016 15:65

    Content type: Research

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  36. To investigate air pollution effects during pregnancy or in the first weeks of life, models are needed that capture both the spatial and temporal variability of air pollution exposures.

    Authors: Elena Proietti, Edgar Delgado-Eckert, Danielle Vienneau, Georgette Stern, Ming-Yi Tsai, Philipp Latzin, Urs Frey and Martin Röösli

    Citation: Environmental Health 2016 15:61

    Content type: Research

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  38. Bisphenol A (BPA) is a ubiquitous, endocrine-disrupting environmental contaminant that increases risk of some adverse developmental effects. Thus, it is important to characterize BPA levels, metabolic fate and...

    Authors: Roy R. Gerona, Janet Pan, Ami R. Zota, Jackie M. Schwartz, Matthew Friesen, Julia A. Taylor, Patricia A. Hunt and Tracey J. Woodruff

    Citation: Environmental Health 2016 15:50

    Content type: Research

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  39. Polybrominated diphenyl ethers are known endocrine disrupting environmental contaminants used as flame retardants. Their levels have increased in humans over the last ten years, raising concerns about their co...

    Authors: Yasmine K. Serme-Gbedo, Nadia Abdelouahab, Jean-Charles Pasquier, Alan A. Cohen and Larissa Takser

    Citation: Environmental Health 2016 15:49

    Content type: Research

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  40. The people of Bangladesh are currently exposed to high concentrations of arsenic and manganese in drinking water, as well as elevated lead in many regions. The objective of this study was to investigate associ...

    Authors: Ema G. Rodrigues, David C. Bellinger, Linda Valeri, Md Omar Sharif Ibne Hasan, Quazi Quamruzzaman, Mostofa Golam, Molly L. Kile, David C. Christiani, Robert O. Wright and Maitreyi Mazumdar

    Citation: Environmental Health 2016 15:44

    Content type: Research

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  41. Cortisol has functions on homeostasis, growth, neurodevelopment, immune function and the stress response. Secretion follows a diurnal rhythm that mediates these processes. Our objective was to examine the asso...

    Authors: Marcela Tamayo y Ortiz, Martha María Téllez-Rojo, Rosalind J. Wright, Brent A. Coull and Robert O. Wright

    Citation: Environmental Health 2016 15:41

    Content type: Research

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  42. Use of mobile (MP) and cordless phones (CP) is common among young children, but whether the resulting radiofrequency exposure affects development of cognitive skills is not known. Small changes have been found...

    Authors: Mary Redmayne, Catherine L. Smith, Geza Benke, Rodney J. Croft, Anna Dalecki, Christina Dimitriadis, Jordy Kaufman, Skye Macleod, Malcolm R. Sim, Rory Wolfe and Michael J. Abramson

    Citation: Environmental Health 2016 15:26

    Content type: Research

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  43. Injuries involving career-technical-vocational education (CTE) are reported to the New Jersey Safe Schools Program online reporting system, the only U.S. State law-based surveillance data for young workers (ag...

    Authors: Alexsandra A. Apostolico and Derek G. Shendell

    Citation: Environmental Health 2016 15:22

    Content type: Research

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  44. Several studies demonstrated a short-term association between ambient temperature and blood pressure. However, few studies have assessed the long-term effect of ambient temperature on children’s blood pressure...

    Authors: Qin Li, Yuming Guo, Dong-Mei Wei, Yi Song, Jie-Yun Song, Jun Ma and Hai-Jun Wang

    Citation: Environmental Health 2016 15:21

    Content type: Research

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  45. Studies emphasize the importance of particulate matter (PM) in the formation of reactive oxygen species and inflammation. We hypothesized that PM exposure during different time windows in pregnancy influences ...

    Authors: Lotte Grevendonk, Bram G. Janssen, Charlotte Vanpoucke, Wouter Lefebvre, Mirjam Hoxha, Valentina Bollati and Tim S. Nawrot

    Citation: Environmental Health 2016 15:10

    Content type: Research

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  47. Blood lead levels have decreased in Mexico since leaded fuel was banned in 1997, but other sources remain, including the use of lead-glazed ceramics for food storage and preparation. Zinc deficiency is present...

    Authors: Alejandra Cantoral, Martha M. Téllez-Rojo, Teresa Shamah Levy, Mauricio Hernández-Ávila, Lourdes Schnaas, Howard Hu, Karen E. Peterson and Adrienne S. Ettinger

    Citation: Environmental Health 2015 14:95

    Content type: Research

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  48. Perfluoroalkyl acids are synthetic compounds widely used in industrial and commercial applications. Laboratory studies suggest that these persistent and bioaccumulative chemicals produce oxidant stress and dam...

    Authors: Anglina Kataria, Howard Trachtman, Laura Malaga-Dieguez and Leonardo Trasande

    Citation: Environmental Health 2015 14:89

    Content type: Research

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  49. Pyrethroid pesticides cause abnormalities in the dopamine system and produce an ADHD phenotype in animal models, with effects accentuated in males versus females. However, data regarding behavioral effects of ...

    Authors: Melissa Wagner-Schuman, Jason R. Richardson, Peggy Auinger, Joseph M. Braun, Bruce P. Lanphear, Jeffery N. Epstein, Kimberly Yolton and Tanya E. Froehlich

    Citation: Environmental Health 2015 14:44

    Content type: Research

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  50. By-products of water disinfectants have been suggested to cause asthma, especially in atopic children. However, studies on indoor swimming pool attendance and asthma in children have presented conflicting resu...

    Authors: Martin Andersson, Linnea Hedman, Gunnar Nordberg, Bertil Forsberg, Kåre Eriksson and Eva Rönmark

    Citation: Environmental Health 2015 14:37

    Content type: Research

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Environmental Health

ISSN: 1476-069X