Pregnant women are exposed to a mixture of endocrine disrupting chemicals (EDCs). Gestational EDC exposures may be associated with changes in fetal growth that elevates the risk for poor health later in life, ...
Authors: Meghan M. Woods, Bruce P. Lanphear, Joseph M. Braun and Lawrence C. McCandless
Extremely high temperatures over many consecutive days have been linked to an increase in renal disease in several cities. This is becoming increasingly relevant with heatwaves becoming longer, more intense, a...
Authors: Matthew Borg, Peng Bi, Monika Nitschke, Susan Williams and Stephen McDonald
Road traffic noise has been associated with adverse health effects including sleep disturbances. Use of sleep medication as an indicator of sleeping problems has rarely been explored in studies of the effects ...
Authors: Jorunn Evandt, Bente Oftedal, Norun Hjertager Krog, Svetlana Skurtveit, Per Nafstad, Per E. Schwarze, Eva Skovlund, Danny Houthuijs and Gunn Marit Aasvang
Influenza peaks during the wintertime in temperate regions and during the annual rainy season in tropical regions – however reasons for the observed differences in disease ecology are poorly understood. We hyp...
Authors: Genee S. Smith, Kyle P. Messier, James L. Crooks, Timothy J. Wade, Cynthia J. Lin and Elizabeth D. Hilborn
Waste is part of the agenda of the European Environment and Health Process and included among the topics of the Sixth Ministerial Conference on Environment and Health. Disposal and management of hazardous wast...
Authors: L. Fazzo, F. Minichilli, M. Santoro, A. Ceccarini, M. Della Seta, F. Bianchi, P. Comba and M. Martuzzi
Persistent organic pollutants (POPs) are environmentally and biologically persistent chemicals that include polybrominated diphenyl ethers (PBDEs), per- and polyfluoroalkyl substances (PFASs), polychlorinated ...
Socioeconomically disadvantaged populations often have higher exposures to particulate air pollution, which can be expected to contribute to differentials in life expectancy. We examined socioeconomic differen...
Authors: Ai Milojevic, Claire L. Niedzwiedz, Jamie Pearce, James Milner, Ian A. MacKenzie, Ruth M. Doherty and Paul Wilkinson
Fecal indicator bacteria used to assess illness risks in recreational waters (e.g., Escherichia coli, Enterococci) cannot discriminate among pollution sources. To address this limitation, human-associated Bactero...
Authors: Melanie D. Napier, Richard Haugland, Charles Poole, Alfred P. Dufour, Jill R. Stewart, David J. Weber, Manju Varma, Jennifer S. Lavender and Timothy J. Wade
There is growing concern of health effects of exposure to pollutant mixtures. We initially proposed an Environmental Risk Score (ERS) as a summary measure to examine the risk of exposure to multi-pollutants in...
Authors: Sung Kyun Park, Zhangchen Zhao and Bhramar Mukherjee
Lung cancer, as the leading cause of cancer mortality worldwide, has been linked to environmental factors, such as air pollution. Residential exposure to petrochemicals is considered a possible cause of lung c...
Authors: Cheng-Kuan Lin, Huei-Yang Hung, David C. Christiani, Francesco Forastiere and Ro-Ting Lin
Organochlorine insecticides (OCs) have historically been used worldwide to control insects, although most have now been banned in developed countries. Evidence for an association between OC exposures and cance...
Authors: Lydia M. Louis, Catherine C. Lerro, Melissa C. Friesen, Gabriella Andreotti, Stella Koutros, Dale P. Sandler, Aaron Blair, Mark G. Robson and Laura E. Beane Freeman
In this review, we examine the continually expanding and increasingly compelling data linking radiation and various chemicals in our environment to the current high incidence of breast cancer.
Authors: Janet M. Gray, Sharima Rasanayagam, Connie Engel and Jeanne Rizzo
China has undergone rapid urbanization in the past three decades. We aimed to report blood lead level (B-Pb) in the most rapidly urbanized Yangtze River Delta Region of China, and explore the association B-Pb ...
Authors: Hualing Zhai, Chi Chen, Ningjian Wang, Yi Chen, Xiaomin Nie, Bing Han, Qin Li, Fangzhen Xia and Yingli Lu
Vibrio parahaemolyticus (Vp) is a naturally occurring bacterium found in marine environments worldwide. It can cause gastrointestinal illness in humans, primarily through raw oyster co...
Authors: Stephanie Konrad, Peggy Paduraru, Pablo Romero-Barrios, Sarah B. Henderson and Eleni Galanis
Epidemiologic studies have raised the possibility that some pesticide compounds induce the neurodegenerative disease amyotrophic lateral sclerosis (ALS), though the available evidence is not entirely consistent.
Authors: Marco Vinceti, Tommaso Filippini, Federica Violi, Kenneth J. Rothman, Sofia Costanzini, Carlotta Malagoli, Lauren A. Wise, Anna Odone, Carlo Signorelli, Laura Iacuzio, Elisa Arcolin, Jessica Mandrioli, Nicola Fini, Francesco Patti, Salvatore Lo Fermo, Vladimiro Pietrini…
Brain tumor etiology is poorly understood. Based on their ability to pass through the blood–brain barrier, it has been hypothesized that exposure to metals may increase the risk of brain cancer. Results from t...
Authors: Marie-Elise Parent, Michelle C. Turner, Jérôme Lavoué, Hugues Richard, Jordi Figuerola, Laurel Kincl, Lesley Richardson, Geza Benke, Maria Blettner, Sarah Fleming, Martine Hours, Daniel Krewski, David McLean, Siegal Sadetzki, Klaus Schlaefer, Brigitte Schlehofer…
Hepatocellular carcinoma (HCC), the most commonly occurring type of primary liver cancer, has been increasing in incidence worldwide. Vitamin D, acquired from sunlight exposure, diet, and dietary supplements, ...
Authors: Trang VoPham, Kimberly A. Bertrand, Jian-Min Yuan, Rulla M. Tamimi, Jaime E. Hart and Francine Laden
Due to their lack of repair capacity mitochondria are critical targets for environmental toxicants. We studied genes and pathways reflecting mitochondrial responses to short- and medium-term PM10 exposure.
Authors: Ellen Winckelmans, Tim S Nawrot, Maria Tsamou, Elly Den Hond, Willy Baeyens, Jos Kleinjans, Wouter Lefebvre, Nicolas Van Larebeke, Martien Peusens, Michelle Plusquin, Hans Reynders, Greet Schoeters, Charlotte Vanpoucke, Theo M de Kok and Karen Vrijens
Hazard identification is a major scientific challenge, notably for environmental epidemiology, and is often surrounded, as the recent case of glyphosate shows, by debate arising in the first place by the inher...
To examine the relationship between cadmium, lead, and mercury concentrations with high-sensitivity C-reactive protein (hs-CRP) and homocysteine in women.
Authors: Anna Z. Pollack, Sunni L. Mumford, Lindsey Sjaarda, Neil J. Perkins, Farah Malik, Jean Wactawski-Wende and Enrique F. Schisterman
Air pollution is involved in many pathologies. These pollutants act through several mechanisms that can affect numerous physiological functions, including reproduction: as endocrine disruptors or reactive oxyg...
Authors: Julie Carré, Nicolas Gatimel, Jessika Moreau, Jean Parinaud and Roger Léandri
Noise-induced hearing loss (NIHL) is a complex disease caused by environmental and genetic risk factors. This study explored the relationship between the genetic variations in the CASP gene and the risk of develo...
Authors: Yinyin Wu, Juntao Ni, Mingjian Qi, Chengjian Cao, Yuxian Shao, Liangwen Xu, Haiyan Ma and Lei Yang
Few epidemiological studies have investigated the link between occupational exposure to solvents and head and neck cancer risk, and available findings are sparse and inconsistent. The objective of this study w...
Authors: Christine Barul, Aurore Fayossé, Matthieu Carton, Corinne Pilorget, Anne-Sophie Woronoff, Isabelle Stücker and Danièle Luce
Exposure to arsenic in drinking water is a global health problem and arsenic-induced skin lesions are hallmark of chronic arsenic toxicity. We and others have reported germline genetic variations as risk facto...
Authors: Muhammad G. Kibriya, Farzana Jasmine, Faruque Parvez, Maria Argos, Shantanu Roy, Rachelle Paul-Brutus, Tariqul Islam, Alauddin Ahmed, Muhammad Rakibuz-Zaman, Justin Shinkle, Vesna Slavkovich, Joseph H. Graziano and Habibul Ahsan
There is growing interest in examining the simultaneous effects of multiple exposures and, more generally, the effects of mixtures of exposures, as part of the exposome concept (being defined as the totality o...
Authors: Jose Barrera-Gómez, Lydiane Agier, Lützen Portengen, Marc Chadeau-Hyam, Lise Giorgis-Allemand, Valérie Siroux, Oliver Robinson, Jelle Vlaanderen, Juan R. González, Mark Nieuwenhuijsen, Paolo Vineis, Martine Vrijheid, Roel Vermeulen, Rémy Slama and Xavier Basagaña
Given the double jeopardy of global increases in rates of obesity and climate change, it is increasingly important to recognise the dangers posed to diabetic patients during periods of extreme weather. We aime...
Authors: S. Hajat, A. Haines, C. Sarran, A. Sharma, C. Bates and L. E. Fleming
Ambient particulate matter (PM) has an adverse effect on respiratory morbidity. Desert dust outbreaks contribute to increased PM levels but the toxicity of desert dust mixed with anthropogenic pollutants needs...
Authors: Stavroula-Myrto Trianti, Evangelia Samoli, Sophia Rodopoulou, Klea Katsouyanni, Spyros A. Papiris and Anna Karakatsani
Adenocarcinoma (AC) is the most common lung cancer among non-smokers, but few studies have assessed the effect of PM2.5 on AC among never smokers. The purpose of this study was to assess the association between a...
Authors: Lida Gharibvand, W. Lawrence Beeson, David Shavlik, Raymond Knutsen, Mark Ghamsary, Samuel Soret and Synnove F. Knutsen
Ionizing radiation is a well-known carcinogen. Chromosome aberrations, and in particular micronuclei represent an early biological predictor of cancer risk. There are well-documented associations of micronucle...
Authors: D. Bazyka, S. C. Finch, I. M. Ilienko, O. Lyaskivska, I. Dyagil, N. Trotsiuk, N. Gudzenko, V. V. Chumak, K. M. Walsh, J. Wiemels, M. P. Little and L.B. Zablotska
Vaginal candidiasis is frequent among pregnant women and it is treated with anti-fungal medication (conazoles). Conazoles have anti-androgenic properties and prenatal exposure in rodents is associated with a s...
Authors: Djamilla Madelung Mogensen, Maria Bergkvist Pihl, Niels E. Skakkebæk, Helle Raun Andersen, Anders Juul, Henriette Boye Kyhl, Shanna Swan, David Møbjerg Kristensen, Marianne Skovager Andersen, Dorte Vesterholm Lind and Tina Kold Jensen
Reduction of child undernutrition is one of the Sustainable Development Goals for 2030. Achievement of this goal may be made more difficult in some settings by climate change through adverse impact on agricult...
Authors: Kristine Belesova, Antonio Gasparrini, Ali Sié, Rainer Sauerborn and Paul Wilkinson
Little is known about the long-term health effects of ambient ultrafine particles (<0.1 μm) (UFPs) including their association with respiratory disease incidence. In this study, we examined the relationship be...
Authors: Scott Weichenthal, Li Bai, Marianne Hatzopoulou, Keith Van Ryswyk, Jeffrey C. Kwong, Michael Jerrett, Aaron van Donkelaar, Randall V. Martin, Richard T. Burnett, Hong Lu and Hong Chen
Daily changes in ambient concentrations of particulate matter, nitrogen oxides and ozone are associated with increased cardiopulmonary morbidity and mortality, with the lungs and their function being a vulnera...
Authors: Luc Int Panis, Eline B Provost, Bianca Cox, Tijs Louwies, Michelle Laeremans, Arnout Standaert, Evi Dons, Luc Holmstock, Tim Nawrot and Patrick De Boever
Evidence shows that both the physical and social environments play a role in the development of cardiovascular disease. The purpose of this systematic review is two-fold: First, we summarize research from the ...
Authors: Christina H. Fuller, Karla R. Feeser, Jeremy A. Sarnat and Marie S. O’Neill
Household air pollution (HAP) from cooking with solid fuels has become a leading cause of death and disability in many developing countries including Bangladesh. We assess the association between HAP and risk ...
Authors: Md Nuruzzaman Khan, Cherri Zhang B. Nurs, M. Mofizul Islam, Md Rafiqul Islam and Md Mizanur Rahman
Environmental Persistent Organic Pollutants (POPs) can alter the hormone homeostasis by mimicking, interfering or blocking the function of hormones; moreover POPs are hypothesized to modify the risk of breast ...
Authors: Maria Wielsøe, Peder Kern and Eva Cecilie Bonefeld-Jørgensen
Numerous studies have found associations between ambient fine particulate matter (PM2.5) and increased mortality risk. However, little evidence is available on associations between PM2.5 and years of life lost (Y...
Authors: Guoxing Li, Jing Huang, Guozhang Xu, Xiaochuan Pan, Xujun Qian, Jiaying Xu, Yan Zhao, Tao Zhang, Qichen Liu, Xinbiao Guo and Tianfeng He
Previous research shows that, besides risk factors in adult life, the early-life environment can influence blood pressure and hypertension in adults. However, the effects of residential traffic exposure and re...
Authors: Esmée M Bijnens, Tim S Nawrot, Ruth JF Loos, Marij Gielen, Robert Vlietinck, Catherine Derom and Maurice P Zeegers
Air pollution exposure during pregnancy has been associated with adverse birth outcomes and health problems later in life. We investigated sex-specific transcriptomic responses to gestational long- and short-t...
Authors: Ellen Winckelmans, Karen Vrijens, Maria Tsamou, Bram G. Janssen, Nelly D. Saenen, Harry A. Roels, Jos Kleinjans, Wouter Lefebvre, Charlotte Vanpoucke, Theo M. de Kok and Tim S. Nawrot
We aimed to assess the content of electronic cigarette (EC) emissions for five groups of potentially toxic compounds that are known to be present in tobacco smoke: nicotine, particles, carbonyls, volatile orga...
Authors: Mi-Sun Lee, Ryan F. LeBouf, Youn-Suk Son, Petros Koutrakis and David C. Christiani
Organophospate flame retardants (PFRs) are chemicals of emerging concern due to restrictions on polybrominated diphenyl ether flame retardant formulations. We describe the occurrence, variability, and predicto...
Authors: Megan E. Romano, Nicola L. Hawley, Melissa Eliot, Antonia M. Calafat, Nayana K. Jayatilaka, Karl Kelsey, Stephen McGarvey, Maureen G. Phipps, David A. Savitz, Erika F. Werner and Joseph M. Braun
Since July 2015, Lebanon has been experiencing a waste management crisis. Dumpsites in inhabited areas and waste burning have emerged due to the waste accumulation, further adding to the gravity of the situati...
Authors: Rami Z. Morsi, Rawan Safa, Serge F. Baroud, Cherine N. Fawaz, Jad I. Farha, Fadi El-Jardali and Monique Chaaya
The disease burden due to heat-stress illness (HSI), which can result in significant morbidity and mortality, is expected to increase as the climate continues to warm. In the United States (U.S.) much of what ...
Authors: Jyotsna S. Jagai, Elena Grossman, Livia Navon, Apostolis Sambanis and Samuel Dorevitch
Because only 25% of cases of premature ovarian insufficiency (POI) have a known etiology, the aim of this review was to summarize the associations and mechanisms of the impact of the environment on this pathol...
Authors: Pauline Vabre, Nicolas Gatimel, Jessika Moreau, Véronique Gayrard, Nicole Picard-Hagen, Jean Parinaud and Roger D. Leandri
Prenatal urinary concentrations of phthalates in women participants in an urban birth cohort were associated with outcomes in their children related to neurodevelopment, autoimmune disease risk, and fat mass a...
Authors: Jennifer J. Adibi, Jessie P. Buckley, Myoung Keun Lee, Paige L. Williams, Allan C. Just, Yaqi Zhao, Hari K. Bhat and Robin M. Whyatt
Lead (Pb) is a toxic substance with well-known, multiple, long-term, adverse health outcomes. Shooting guns at firing ranges is an occupational necessity for security personnel, police officers, members of the...
Authors: Mark A. S. Laidlaw, Gabriel Filippelli, Howard Mielke, Brian Gulson and Andrew S. Ball
The present study is an attempt to explore the association between kitchen indoor air pollutants and physiological profiles in kitchen workers with microalbuminuria (MAU) in north India (Lucknow) and south Ind...
Cold spells and heatwaves increase mortality. However little is known about the effect of heatwaves or cold spells on cardiovascular morbidity. This study aims to assess the effect of cold spells and heatwaves...
Authors: Anna Ponjoan, Jordi Blanch, Lia Alves-Cabratosa, Ruth Martí-Lluch, Marc Comas-Cufí, Dídac Parramon, María del Mar Garcia-Gil, Rafel Ramos and Irene Petersen
Environmental exposures and immune conditions during pregnancy could influence development of autism spectrum disorder (ASD) in offspring. However, few studies have examined immune-triggering exposures in rela...
Authors: Alison B. Singer, Igor Burstyn, Malene Thygesen, Preben Bo Mortensen, M. Daniele Fallin and Diana E. Schendel
