There is growing concern of health effects of exposure to pollutant mixtures. We initially proposed an Environmental Risk Score (ERS) as a summary measure to examine the risk of exposure to multi-pollutants in...
Authors: Sung Kyun Park, Zhangchen Zhao and Bhramar Mukherjee
Organochlorine insecticides (OCs) have historically been used worldwide to control insects, although most have now been banned in developed countries. Evidence for an association between OC exposures and cance...
Authors: Lydia M. Louis, Catherine C. Lerro, Melissa C. Friesen, Gabriella Andreotti, Stella Koutros, Dale P. Sandler, Aaron Blair, Mark G. Robson and Laura E. Beane Freeman
In this review, we examine the continually expanding and increasingly compelling data linking radiation and various chemicals in our environment to the current high incidence of breast cancer.
Authors: Janet M. Gray, Sharima Rasanayagam, Connie Engel and Jeanne Rizzo
China has undergone rapid urbanization in the past three decades. We aimed to report blood lead level (B-Pb) in the most rapidly urbanized Yangtze River Delta Region of China, and explore the association B-Pb ...
Authors: Hualing Zhai, Chi Chen, Ningjian Wang, Yi Chen, Xiaomin Nie, Bing Han, Qin Li, Fangzhen Xia and Yingli Lu
Vibrio parahaemolyticus (Vp) is a naturally occurring bacterium found in marine environments worldwide. It can cause gastrointestinal illness in humans, primarily through raw oyster co...
Authors: Stephanie Konrad, Peggy Paduraru, Pablo Romero-Barrios, Sarah B. Henderson and Eleni Galanis
Epidemiologic studies have raised the possibility that some pesticide compounds induce the neurodegenerative disease amyotrophic lateral sclerosis (ALS), though the available evidence is not entirely consistent.
Authors: Marco Vinceti, Tommaso Filippini, Federica Violi, Kenneth J. Rothman, Sofia Costanzini, Carlotta Malagoli, Lauren A. Wise, Anna Odone, Carlo Signorelli, Laura Iacuzio, Elisa Arcolin, Jessica Mandrioli, Nicola Fini, Francesco Patti, Salvatore Lo Fermo, Vladimiro Pietrini…
Brain tumor etiology is poorly understood. Based on their ability to pass through the blood–brain barrier, it has been hypothesized that exposure to metals may increase the risk of brain cancer. Results from t...
Authors: Marie-Elise Parent, Michelle C. Turner, Jérôme Lavoué, Hugues Richard, Jordi Figuerola, Laurel Kincl, Lesley Richardson, Geza Benke, Maria Blettner, Sarah Fleming, Martine Hours, Daniel Krewski, David McLean, Siegal Sadetzki, Klaus Schlaefer, Brigitte Schlehofer…
Hepatocellular carcinoma (HCC), the most commonly occurring type of primary liver cancer, has been increasing in incidence worldwide. Vitamin D, acquired from sunlight exposure, diet, and dietary supplements, ...
Authors: Trang VoPham, Kimberly A. Bertrand, Jian-Min Yuan, Rulla M. Tamimi, Jaime E. Hart and Francine Laden
Due to their lack of repair capacity mitochondria are critical targets for environmental toxicants. We studied genes and pathways reflecting mitochondrial responses to short- and medium-term PM10 exposure.
Authors: Ellen Winckelmans, Tim S Nawrot, Maria Tsamou, Elly Den Hond, Willy Baeyens, Jos Kleinjans, Wouter Lefebvre, Nicolas Van Larebeke, Martien Peusens, Michelle Plusquin, Hans Reynders, Greet Schoeters, Charlotte Vanpoucke, Theo M de Kok and Karen Vrijens
Hazard identification is a major scientific challenge, notably for environmental epidemiology, and is often surrounded, as the recent case of glyphosate shows, by debate arising in the first place by the inher...
To examine the relationship between cadmium, lead, and mercury concentrations with high-sensitivity C-reactive protein (hs-CRP) and homocysteine in women.
Authors: Anna Z. Pollack, Sunni L. Mumford, Lindsey Sjaarda, Neil J. Perkins, Farah Malik, Jean Wactawski-Wende and Enrique F. Schisterman
Air pollution is involved in many pathologies. These pollutants act through several mechanisms that can affect numerous physiological functions, including reproduction: as endocrine disruptors or reactive oxyg...
Authors: Julie Carré, Nicolas Gatimel, Jessika Moreau, Jean Parinaud and Roger Léandri
Noise-induced hearing loss (NIHL) is a complex disease caused by environmental and genetic risk factors. This study explored the relationship between the genetic variations in the CASP gene and the risk of develo...
Authors: Yinyin Wu, Juntao Ni, Mingjian Qi, Chengjian Cao, Yuxian Shao, Liangwen Xu, Haiyan Ma and Lei Yang
Few epidemiological studies have investigated the link between occupational exposure to solvents and head and neck cancer risk, and available findings are sparse and inconsistent. The objective of this study w...
Authors: Christine Barul, Aurore Fayossé, Matthieu Carton, Corinne Pilorget, Anne-Sophie Woronoff, Isabelle Stücker and Danièle Luce
Exposure to arsenic in drinking water is a global health problem and arsenic-induced skin lesions are hallmark of chronic arsenic toxicity. We and others have reported germline genetic variations as risk facto...
Authors: Muhammad G. Kibriya, Farzana Jasmine, Faruque Parvez, Maria Argos, Shantanu Roy, Rachelle Paul-Brutus, Tariqul Islam, Alauddin Ahmed, Muhammad Rakibuz-Zaman, Justin Shinkle, Vesna Slavkovich, Joseph H. Graziano and Habibul Ahsan
There is growing interest in examining the simultaneous effects of multiple exposures and, more generally, the effects of mixtures of exposures, as part of the exposome concept (being defined as the totality o...
Authors: Jose Barrera-Gómez, Lydiane Agier, Lützen Portengen, Marc Chadeau-Hyam, Lise Giorgis-Allemand, Valérie Siroux, Oliver Robinson, Jelle Vlaanderen, Juan R. González, Mark Nieuwenhuijsen, Paolo Vineis, Martine Vrijheid, Roel Vermeulen, Rémy Slama and Xavier Basagaña
Given the double jeopardy of global increases in rates of obesity and climate change, it is increasingly important to recognise the dangers posed to diabetic patients during periods of extreme weather. We aime...
Authors: S. Hajat, A. Haines, C. Sarran, A. Sharma, C. Bates and L. E. Fleming
Ambient particulate matter (PM) has an adverse effect on respiratory morbidity. Desert dust outbreaks contribute to increased PM levels but the toxicity of desert dust mixed with anthropogenic pollutants needs...
Authors: Stavroula-Myrto Trianti, Evangelia Samoli, Sophia Rodopoulou, Klea Katsouyanni, Spyros A. Papiris and Anna Karakatsani
Adenocarcinoma (AC) is the most common lung cancer among non-smokers, but few studies have assessed the effect of PM2.5 on AC among never smokers. The purpose of this study was to assess the association between a...
Authors: Lida Gharibvand, W. Lawrence Beeson, David Shavlik, Raymond Knutsen, Mark Ghamsary, Samuel Soret and Synnove F. Knutsen
Ionizing radiation is a well-known carcinogen. Chromosome aberrations, and in particular micronuclei represent an early biological predictor of cancer risk. There are well-documented associations of micronucle...
Authors: D. Bazyka, S. C. Finch, I. M. Ilienko, O. Lyaskivska, I. Dyagil, N. Trotsiuk, N. Gudzenko, V. V. Chumak, K. M. Walsh, J. Wiemels, M. P. Little and L.B. Zablotska
Vaginal candidiasis is frequent among pregnant women and it is treated with anti-fungal medication (conazoles). Conazoles have anti-androgenic properties and prenatal exposure in rodents is associated with a s...
Authors: Djamilla Madelung Mogensen, Maria Bergkvist Pihl, Niels E. Skakkebæk, Helle Raun Andersen, Anders Juul, Henriette Boye Kyhl, Shanna Swan, David Møbjerg Kristensen, Marianne Skovager Andersen, Dorte Vesterholm Lind and Tina Kold Jensen
Reduction of child undernutrition is one of the Sustainable Development Goals for 2030. Achievement of this goal may be made more difficult in some settings by climate change through adverse impact on agricult...
Authors: Kristine Belesova, Antonio Gasparrini, Ali Sié, Rainer Sauerborn and Paul Wilkinson
Little is known about the long-term health effects of ambient ultrafine particles (<0.1 μm) (UFPs) including their association with respiratory disease incidence. In this study, we examined the relationship be...
Authors: Scott Weichenthal, Li Bai, Marianne Hatzopoulou, Keith Van Ryswyk, Jeffrey C. Kwong, Michael Jerrett, Aaron van Donkelaar, Randall V. Martin, Richard T. Burnett, Hong Lu and Hong Chen
Daily changes in ambient concentrations of particulate matter, nitrogen oxides and ozone are associated with increased cardiopulmonary morbidity and mortality, with the lungs and their function being a vulnera...
Authors: Luc Int Panis, Eline B Provost, Bianca Cox, Tijs Louwies, Michelle Laeremans, Arnout Standaert, Evi Dons, Luc Holmstock, Tim Nawrot and Patrick De Boever
Evidence shows that both the physical and social environments play a role in the development of cardiovascular disease. The purpose of this systematic review is two-fold: First, we summarize research from the ...
Authors: Christina H. Fuller, Karla R. Feeser, Jeremy A. Sarnat and Marie S. O’Neill
Household air pollution (HAP) from cooking with solid fuels has become a leading cause of death and disability in many developing countries including Bangladesh. We assess the association between HAP and risk ...
Authors: Md Nuruzzaman Khan, Cherri Zhang B. Nurs, M. Mofizul Islam, Md Rafiqul Islam and Md Mizanur Rahman
Environmental Persistent Organic Pollutants (POPs) can alter the hormone homeostasis by mimicking, interfering or blocking the function of hormones; moreover POPs are hypothesized to modify the risk of breast ...
Authors: Maria Wielsøe, Peder Kern and Eva Cecilie Bonefeld-Jørgensen
Numerous studies have found associations between ambient fine particulate matter (PM2.5) and increased mortality risk. However, little evidence is available on associations between PM2.5 and years of life lost (Y...
Authors: Guoxing Li, Jing Huang, Guozhang Xu, Xiaochuan Pan, Xujun Qian, Jiaying Xu, Yan Zhao, Tao Zhang, Qichen Liu, Xinbiao Guo and Tianfeng He
Previous research shows that, besides risk factors in adult life, the early-life environment can influence blood pressure and hypertension in adults. However, the effects of residential traffic exposure and re...
Authors: Esmée M Bijnens, Tim S Nawrot, Ruth JF Loos, Marij Gielen, Robert Vlietinck, Catherine Derom and Maurice P Zeegers
Air pollution exposure during pregnancy has been associated with adverse birth outcomes and health problems later in life. We investigated sex-specific transcriptomic responses to gestational long- and short-t...
Authors: Ellen Winckelmans, Karen Vrijens, Maria Tsamou, Bram G. Janssen, Nelly D. Saenen, Harry A. Roels, Jos Kleinjans, Wouter Lefebvre, Charlotte Vanpoucke, Theo M. de Kok and Tim S. Nawrot
We aimed to assess the content of electronic cigarette (EC) emissions for five groups of potentially toxic compounds that are known to be present in tobacco smoke: nicotine, particles, carbonyls, volatile orga...
Authors: Mi-Sun Lee, Ryan F. LeBouf, Youn-Suk Son, Petros Koutrakis and David C. Christiani
Organophospate flame retardants (PFRs) are chemicals of emerging concern due to restrictions on polybrominated diphenyl ether flame retardant formulations. We describe the occurrence, variability, and predicto...
Authors: Megan E. Romano, Nicola L. Hawley, Melissa Eliot, Antonia M. Calafat, Nayana K. Jayatilaka, Karl Kelsey, Stephen McGarvey, Maureen G. Phipps, David A. Savitz, Erika F. Werner and Joseph M. Braun
Since July 2015, Lebanon has been experiencing a waste management crisis. Dumpsites in inhabited areas and waste burning have emerged due to the waste accumulation, further adding to the gravity of the situati...
Authors: Rami Z. Morsi, Rawan Safa, Serge F. Baroud, Cherine N. Fawaz, Jad I. Farha, Fadi El-Jardali and Monique Chaaya
The disease burden due to heat-stress illness (HSI), which can result in significant morbidity and mortality, is expected to increase as the climate continues to warm. In the United States (U.S.) much of what ...
Authors: Jyotsna S. Jagai, Elena Grossman, Livia Navon, Apostolis Sambanis and Samuel Dorevitch
Because only 25% of cases of premature ovarian insufficiency (POI) have a known etiology, the aim of this review was to summarize the associations and mechanisms of the impact of the environment on this pathol...
Authors: Pauline Vabre, Nicolas Gatimel, Jessika Moreau, Véronique Gayrard, Nicole Picard-Hagen, Jean Parinaud and Roger D. Leandri
Prenatal urinary concentrations of phthalates in women participants in an urban birth cohort were associated with outcomes in their children related to neurodevelopment, autoimmune disease risk, and fat mass a...
Authors: Jennifer J. Adibi, Jessie P. Buckley, Myoung Keun Lee, Paige L. Williams, Allan C. Just, Yaqi Zhao, Hari K. Bhat and Robin M. Whyatt
Lead (Pb) is a toxic substance with well-known, multiple, long-term, adverse health outcomes. Shooting guns at firing ranges is an occupational necessity for security personnel, police officers, members of the...
Authors: Mark A. S. Laidlaw, Gabriel Filippelli, Howard Mielke, Brian Gulson and Andrew S. Ball
The present study is an attempt to explore the association between kitchen indoor air pollutants and physiological profiles in kitchen workers with microalbuminuria (MAU) in north India (Lucknow) and south Ind...
Cold spells and heatwaves increase mortality. However little is known about the effect of heatwaves or cold spells on cardiovascular morbidity. This study aims to assess the effect of cold spells and heatwaves...
Authors: Anna Ponjoan, Jordi Blanch, Lia Alves-Cabratosa, Ruth Martí-Lluch, Marc Comas-Cufí, Dídac Parramon, María del Mar Garcia-Gil, Rafel Ramos and Irene Petersen
Environmental exposures and immune conditions during pregnancy could influence development of autism spectrum disorder (ASD) in offspring. However, few studies have examined immune-triggering exposures in rela...
Authors: Alison B. Singer, Igor Burstyn, Malene Thygesen, Preben Bo Mortensen, M. Daniele Fallin and Diana E. Schendel
Occupational exposures to ultrafine particles in the plume generated during laser hair removal procedures, the most commonly performed light based cosmetic procedure, have not been thoroughly characterized. Ac...
Authors: Emily J. Eshleman, Mallory LeBlanc, Lisa B. Rokoff, Yinyin Xu, Rui Hu, Kachiu Lee, Gary S. Chuang, Gary Adamkiewicz and Jaime E. Hart
Environmental lead exposure among adults may increase blood pressure and elevate the risk of hypertension. The availability of data on blood lead levels (BLL) in adult Brazilian population is scarce and popula...
Authors: Ana Carolina Bertin de Almeida Lopes, Ellen Kovner Silbergeld, Ana Navas-Acien, Rachel Zamoiski, Airton da Cunha Martins Jr., Alissana Ester Iakmiu Camargo, Mariana Ragassi Urbano, Arthur Eumann Mesas and Monica Maria Bastos Paoliello
Investigating the effects of prenatal and childhood exposures on behavioral health outcomes in adolescence is challenging given the lengthy period between the exposure and outcomes. We conducted a retrospectiv...
Authors: Lisa G. Gallagher, Thomas F. Webster and Ann Aschengrau
Particle exposure is a risk factor for cardiovascular diseases. Mitochondrial DNA (mtDNA) is a primary target for oxidative stress generated by particle exposure. We aimed to elucidate the effects of occupatio...
Authors: Yiyi Xu, Huiqi Li, Maria Hedmer, Mohammad Bakhtiar Hossain, Håkan Tinnerberg, Karin Broberg and Maria Albin
Heart failure (HF) is a significant source of morbidity and mortality among African Americans. Ambient air pollution, including from traffic, is associated with HF, but the mechanisms remain unknown. The objec...
Authors: Anne M. Weaver, Gregory A. Wellenius, Wen-Chih Wu, DeMarc A. Hickson, Masoor Kamalesh and Yi Wang
Polychlorinated biphenyls (PCBs) and metals (lead and cadmium) are neurotoxic and affect neurobehavioral performance. Yet little is known about the association between exposure to multiple neurotoxic compounds...
Authors: Jennifer Przybyla, E. Andres Houseman, Ellen Smit and Molly L. Kile
From 1963–1995, a factory in Willits, Mendocino County, CA used toxic hexavalent chromium (Cr(VI)) without adequate measures to protect the population. We use longitudinal hospital data to compare reproductive...
Mercury is a toxic heavy metal and is known to affect many diseases. However, few studies have examined the effects of mercury exposure on liver function in the general population. We examined the association ...
Authors: Mee-Ri Lee, Youn-Hee Lim, Bo-Eun Lee and Yun-Chul Hong
A statistical association between ambient air pollution and suicide mortality has been recently reported in Environmental Health, which seems not to be scientifically supported by their data.
