Ambient pollutants, polymorphisms associated with microRNA processing and adhesion molecules: the Normative Aging Study

Table 5 Main effects of SNPs with unadjusted p-value ≤0.1

	homozygous carriers/common allele carriers	% change	95%CI		p-value
sICAM
rs13078	21/677	10.0	(-0.1,	21.1)	0.05
sVCAM-1
rs910925	116/604	6.3	(0.6,	12.3)	0.03
rs7813	116/597	6.1	(0.4,	12.1)	0.04

†unadjusted p-values are reported here. No SNPs identified in main effects analysis were statistically significant at the 0.05 level in models adjusted for multiple testing. models adjusted for education (≤12 years, 13-16 years, >16 years), ≥2 alcoholic drinks per day, age at first adhesion molecule measurement, time since first measurement, body mass index (BMI), diabetes or fasting glucose >126 mg/dL, smoking status, pack-years smoked, hypertension medication use (yes/no), statin use, apparent temperature, seasonality (sine and cosine of month), CRP >10 mg/L.

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