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Evaluating adverse effects of environmental agents in food: a brief critique of the US FDA’s criteria

Evaluating adverse effects of environmental agents in food:

Authors: Laura N. Vandenberg et al. 

Citation: Environmental Health 2023 22:38 Published on: 21 April 2023

In the US, the Food and Drug Administration (US FDA) is charged with protecting the safety of food from both pathogens and chemicals used in food production and food packaging. To protect the public in a transparent manner, the FDA needs to have an operational definition of what it considers to be an “adverse effect” so that it can take action against harmful agents. The FDA has recently published two statements where, for the first time, it defines the characteristics of an adverse effect that it uses to interpret toxicity studies.

The effect of high polycyclic aromatic hydrocarbon exposure on biological aging indicators

New Content ItemAuthors: Manuela Campisi et al.

Citation: Environmental Health 2023 22:27 Published on: 17 March 2023

Aging represents a serious health and socioeconomic concern for our society. However, not all people age in the same way and air pollution has been shown to largely impact this process. This article explored whether polycyclic aromatic hydrocarbons (PAHs), excellent fossil and wood burning tracers, accelerate biological aging detected by lymphocytes DNA methylation age (DNAmAge) and telomere length (TL), early nuclear DNA (nDNA) hallmarks of non-mitotic and mitotic cellular aging, and mitochondrial DNA copy number (mtDNAcn).

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Call for papers: Environmental justice and policy research

Top left to right: © aquatarkus /, © narongcp / Fotolia, © olando / Bottom left to right:  © sushytska /, © Turbowerner /, © borgogniels / Getty Images / iStockEnvironmental justice is the fair treatment and meaningful involvement of all people in regards to environmental laws, regulations and protection from environmental health hazards. Environmental Health calls for papers in this subject area which will be a part of a cross-journal collection. 

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Philippe Grandjean, University of Southern Denmark, Denmark

David Ozonoff, Boston University School of Public Health, USA

Aims and scope

Environmental Health publishes manuscripts on important aspects of environmental and occupational medicine and related studies in toxicology and epidemiology that elucidate the health implications of exposures to environmental hazards. Environmental Health articles are published with open access, and the journal practices open peer review.

The journal is aimed at scientists and practitioners in all areas of environmental science in which human health and well-being are involved, either directly or indirectly, and with a view to improving the prevention of environmentally-related risks to human health. Environmental Health is a public health journal serving the public health community and scientists working on matters of public health interest and importance pertaining to the environment.

Announcing the launch of In Review

Environmental Health, in partnership with Research Square, is now offering In Review. Authors choosing this free optional service will be able to:

  • Share their work with fellow researchers to read, comment on, and cite even before publication
  • Showcase their work to funders and others with a citable DOI while it is still under review
  • Track their manuscript - including seeing when reviewers are invited, and when reports are received 

Read more about the full range of benefits of In Review and how to opt in, or see the In Review platform for yourself here.

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Open Peer Review policy

Environmental Health operates an open peer-review system, where the reviewers' names are included on the peer review reports for authors. For more information, see our peer-review policy.  

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