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  1. Research

    Transcriptome-wide analyses indicate mitochondrial responses to particulate air pollution exposure

    Due to their lack of repair capacity mitochondria are critical targets for environmental toxicants. We studied genes and pathways reflecting mitochondrial responses to short- and medium-term PM10 exposure.

    Ellen Winckelmans, Tim S Nawrot, Maria Tsamou, Elly Den Hond, Willy Baeyens, Jos Kleinjans, Wouter Lefebvre, Nicolas Van Larebeke, Martien Peusens, Michelle Plusquin, Hans Reynders, Greet Schoeters, Charlotte Vanpoucke, Theo M de Kok and Karen Vrijens

    Environmental Health 2017 16:87

    Published on: 18 August 2017

  2. Research

    Genetic and epigenetic susceptibility of airway inflammation to PM2.5 in school children: new insights from quantile regression

    The fractional concentration of exhaled nitric oxide (FeNO) is a biomarker of airway inflammation that has proved to be useful in investigations of genetic and epigenetic airway susceptibility to ambient air p...

    Yue Zhang, Muhammad T. Salam, Kiros Berhane, Sandrah P. Eckel, Edward B. Rappaport, William S. Linn, Rima Habre, Theresa M. Bastain and Frank D. Gilliland

    Environmental Health 2017 16:88

    Published on: 18 August 2017

  3. Research

    Maternal occupational exposure and oral clefts in offspring

    Previous studies suggest that periconceptional maternal occupational exposure to solvents and pesticides increase the risk of oral clefts in the offspring. Less is known about the effect of occupational exposu...

    Nynke Spinder, Jorieke E. H. Bergman, H. Marike Boezen, Roel C. H. Vermeulen, Hans Kromhout and Hermien E. K. de Walle

    Environmental Health 2017 16:83

    Published on: 4 August 2017

  4. Research

    Genome-wide gene by lead exposure interaction analysis identifies UNC5D as a candidate gene for neurodevelopment

    Neurodevelopment is a complex process involving both genetic and environmental factors. Prenatal exposure to lead (Pb) has been associated with lower performance on neurodevelopmental tests. Adverse neurodevel...

    Zhaoxi Wang, Birgit Claus Henn, Chaolong Wang, Yongyue Wei, Li Su, Ryan Sun, Han Chen, Peter J. Wagner, Quan Lu, Xihong Lin, Robert Wright, David Bellinger, Molly Kile, Maitreyi Mazumdar, Martha Maria Tellez-Rojo, Lourdes Schnaas…

    Environmental Health 2017 16:81

    Published on: 28 July 2017

  5. Review

    Does air pollution play a role in infertility?: a systematic review

    Air pollution is involved in many pathologies. These pollutants act through several mechanisms that can affect numerous physiological functions, including reproduction: as endocrine disruptors or reactive oxyg...

    Julie Carré, Nicolas Gatimel, Jessika Moreau, Jean Parinaud and Roger Léandri

    Environmental Health 2017 16:82

    Published on: 28 July 2017

  6. Research

    Occupational exposure to chlorinated solvents and risk of head and neck cancer in men: a population-based case-control study in France

    Few epidemiological studies have investigated the link between occupational exposure to solvents and head and neck cancer risk, and available findings are sparse and inconsistent. The objective of this study w...

    Christine Barul, Aurore Fayossé, Matthieu Carton, Corinne Pilorget, Anne-Sophie Woronoff, Isabelle Stücker and Danièle Luce

    Environmental Health 2017 16:77

    Published on: 24 July 2017

  7. Research

    Associations of genetic variation in CASP3 gene with noise-induced hearing loss in a Chinese population: a case–control study

    Noise-induced hearing loss (NIHL) is a complex disease caused by environmental and genetic risk factors. This study explored the relationship between the genetic variations in the CASP gene and the risk of develo...

    Yinyin Wu, Juntao Ni, Mingjian Qi, Chengjian Cao, Yuxian Shao, Liangwen Xu, Haiyan Ma and Lei Yang

    Environmental Health 2017 16:78

    Published on: 24 July 2017

  8. Research

    Ambulatory monitoring demonstrates an acute association between cookstove-related carbon monoxide and blood pressure in a Ghanaian cohort

    Repeated exposure to household air pollution may intermittently raise blood pressure (BP) and affect cardiovascular outcomes. We investigated whether hourly carbon monoxide (CO) exposures were associated with ...

    Ashlinn K. Quinn, Kenneth Ayuurebobi Ae-Ngibise, Patrick L. Kinney, Seyram Kaali, Blair J. Wylie, Ellen Boamah, Daichi Shimbo, Oscar Agyei, Steven N. Chillrud, Mohammed Mujtaba, Joseph E. Schwartz, Marwah Abdalla, Seth Owusu-Agyei, Darby W. Jack and Kwaku Poku Asante

    Environmental Health 2017 16:76

    Published on: 21 July 2017

  9. Research

    Association between genome-wide copy number variation and arsenic-induced skin lesions: a prospective study

    Exposure to arsenic in drinking water is a global health problem and arsenic-induced skin lesions are hallmark of chronic arsenic toxicity. We and others have reported germline genetic variations as risk facto...

    Muhammad G. Kibriya, Farzana Jasmine, Faruque Parvez, Maria Argos, Shantanu Roy, Rachelle Paul-Brutus, Tariqul Islam, Alauddin Ahmed, Muhammad Rakibuz-Zaman, Justin Shinkle, Vesna Slavkovich, Joseph H. Graziano and Habibul Ahsan

    Environmental Health 2017 16:75

    Published on: 18 July 2017

  10. Research

    A systematic comparison of statistical methods to detect interactions in exposome-health associations

    There is growing interest in examining the simultaneous effects of multiple exposures and, more generally, the effects of mixtures of exposures, as part of the exposome concept (being defined as the totality o...

    Jose Barrera-Gómez, Lydiane Agier, Lützen Portengen, Marc Chadeau-Hyam, Lise Giorgis-Allemand, Valérie Siroux, Oliver Robinson, Jelle Vlaanderen, Juan R. González, Mark Nieuwenhuijsen, Paolo Vineis, Martine Vrijheid, Roel Vermeulen, Rémy Slama and Xavier Basagaña

    Environmental Health 2017 16:74

    Published on: 14 July 2017

  11. Research

    Desert dust outbreaks and respiratory morbidity in Athens, Greece

    Ambient particulate matter (PM) has an adverse effect on respiratory morbidity. Desert dust outbreaks contribute to increased PM levels but the toxicity of desert dust mixed with anthropogenic pollutants needs...

    Stavroula-Myrto Trianti, Evangelia Samoli, Sophia Rodopoulou, Klea Katsouyanni, Spyros A. Papiris and Anna Karakatsani

    Environmental Health 2017 16:72

    Published on: 1 July 2017

  12. Research

    The association between ambient fine particulate matter and incident adenocarcinoma subtype of lung cancer

    Adenocarcinoma (AC) is the most common lung cancer among non-smokers, but few studies have assessed the effect of PM2.5 on AC among never smokers. The purpose of this study was to assess the association between a...

    Lida Gharibvand, W. Lawrence Beeson, David Shavlik, Raymond Knutsen, Mark Ghamsary, Samuel Soret and Synnove F. Knutsen

    Environmental Health 2017 16:71

    Published on: 24 June 2017

  13. Research

    Buccal mucosa micronuclei counts in relation to exposure to low dose-rate radiation from the Chornobyl nuclear accident and other medical and occupational radiation exposures

    Ionizing radiation is a well-known carcinogen. Chromosome aberrations, and in particular micronuclei represent an early biological predictor of cancer risk. There are well-documented associations of micronucle...

    D. Bazyka, S. C. Finch, I. M. Ilienko, O. Lyaskivska, I. Dyagil, N. Trotsiuk, N. Gudzenko, V. V. Chumak, K. M. Walsh, J. Wiemels, M. P. Little and L.B. Zablotska

    Environmental Health 2017 16:70

    Published on: 23 June 2017

  14. Research

    Ancient water bottle use and polycyclic aromatic hydrocarbon (PAH) exposure among California Indians: a prehistoric health risk assessment

    Polycyclic aromatic hydrocarbons (PAHs) are the main toxic compounds in natural bitumen, a fossil material used by modern and ancient societies around the world. The adverse health effects of PAHs on modern hu...

    Sabrina B. Sholts, Kevin Smith, Cecilia Wallin, Trifa M. Ahmed and Sebastian K. T. S. Wärmländer

    Environmental Health 2017 16:61

    Published on: 23 June 2017

  15. Research

    Impact of phthalate and BPA exposure during in utero windows of susceptibility on reproductive hormones and sexual maturation in peripubertal males

    Phthalates and BPA are endocrine disrupting chemicals (EDCs) widely used in consumer products. Evidence suggests that phthalate and BPA exposure alters steroid hormone levels in adults, while in utero exposure...

    Deborah J. Watkins, Brisa N. Sánchez, Martha Maria Téllez-Rojo, Joyce M. Lee, Adriana Mercado-García, Clara Blank-Goldenberg, Karen E. Peterson and John D. Meeker

    Environmental Health 2017 16:69

    Published on: 21 June 2017

  16. Research

    Prenatal exposure to antifungal medication may change anogenital distance in male offspring: a preliminary study

    Vaginal candidiasis is frequent among pregnant women and it is treated with anti-fungal medication (conazoles). Conazoles have anti-androgenic properties and prenatal exposure in rodents is associated with a s...

    Djamilla Madelung Mogensen, Maria Bergkvist Pihl, Niels E. Skakkebæk, Helle Raun Andersen, Anders Juul, Henriette Boye Kyhl, Shanna Swan, David Møbjerg Kristensen, Marianne Skovager Andersen, Dorte Vesterholm Lind and Tina Kold Jensen

    Environmental Health 2017 16:68

    Published on: 21 June 2017

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