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Table 2 Functional categories significantly over-represented in the up- or down-modulated genes at 35 days of age by the effects of in uter o exposure to low dose of BBP

From: In utero exposure to butyl benzyl phthalate induces modifications in the morphology and the gene expression profile of the mammary gland: an experimental study in rats

 

Function

GO

p-value

Up-modulated

signal transduction

GO:0007165

6.86E-04

  

GO:0007242

 
 

cell communication

GO:0007154

9.62E-04

 

metabolic process

GO:0008152

2.64E-03

  

GO:0044238

 
 

apoptosis

GO:0006915

3.68E-03

 

transport

GO:0006810

6.42E-03

 

cellular process

GO:0009987

7.55E-03

 

other

GO:0008015

1.30E-03

  

GO:0006936

1.34E-03

Down-modulated

primary metabolic process

GO:0044238

2.00E-06

  

GO:0008152, GO:0006139,

GO:0005975, GO:0019538

 
 

cellular process

GO:0009987

3.63E-05

 

transport

GO:0006810

1.44E-04

  

GO:0006886, GO:0015031,

GO:0006897, GO:0016192

 
 

cell cycle

GO:0007049

1.84E-03

  

GO:0007067

 
 

immune system process

GO:0002376

2.64E-03

 

cell-matrix adhesion

GO:0007160

3.05E-03

 

apoptosis

GO:0006915

4.63E-03

 

other

GO:0007269

5.80E-03

  

GO:0007059

6.14E-03

  1. GO, Gene Ontology class.