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Table 3 Coverage of nominal 95% confidence intervals for the mean exposure magnitude, μ

From: Estimating equations for biomarker based exposure estimation under non-steady-state conditions

 

Exposure Frequency

       

Sample Size

0.1

0.2

0.3

0.4

0.5

0.6

0.7

0.8

0.9

2

94.5%

94.7%

94.8%

94.8%

94.3%

94.0%

94.1%

93.7%

91.0%

4

94.9%

95.0%

94.8%

95.0%

94.8%

94.6%

94.7%

93.8%

91.9%

8

95.3%

95.5%

94.9%

95.2%

94.9%

94.4%

94.6%

94.4%

93.2%

16

95.3%

95.3%

95.2%

94.9%

95.2%

94.9%

94.8%

94.0%

93.4%

32

95.1%

95.5%

95.3%

95.1%

95.1%

94.7%

94.8%

94.4%

94.2%

64

95.1%

95.2%

95.7%

94.8%

94.9%

94.5%

94.5%

94.5%

94.3%

128

95.2%

94.9%

95.1%

95.1%

95.2%

94.6%

94.8%

94.4%

94.9%

256

95.2%

95.1%

95.2%

94.9%

95.1%

95.2%

94.9%

95.0%

94.9%

512

95.5%

95.3%

95.2%

94.5%

94.9%

94.8%

94.8%

95.0%

95.4%

1024

95.1%

94.9%

95.0%

94.3%

95.2%

95.2%

94.9%

94.9%

94.7%