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Table 2 Serum levels of POPs and blood metals in breast cancer patients and controls

From: Perfluorinated compounds are related to breast cancer risk in greenlandic inuit: A case control study

 

Cases

Controls

p value

 

N (n)

median

95% CI

Min-max

N (n)

median

95% CI

Min-max

 

POPs

         

PFOS(ng/ml)

31(31)

45.6

45.7; 69.3

11.6-124

115(98)

21.9

31.1; 46.0

1.5-172

<0.0001

PFOA(ng/ml)

31(31)

2.5

2.2; 3.4

0.2-7.2

115(98)

1.6

2.11; 2.9

0.2-7. 6

0.04

Sum PFSA(ng/ml)

31(31)

48.2

49.6; 74.6

13.2-133

115(98)

24.6

33.7; 49.7

2.0-184

<0.0001

Sum PFCA(ng/ml)

31(31)

8.0

7.9; 11.9

3.3-21.4

115(98)

5.2

6.4; 9.2

1.0-28.1

0.001

Sum PCB(μg/kg lipid)

31(30)

2049

1596; 2870

150.5-6528

115(115)

1867

1759; 2203

92.7-5640

0.69

   < 920 (μg/kg lipid)

10

548

386; 734

151-857

23

451

379; 581

92.7-893

0.41

   920-1745(μg/kg lipid)

4

1343

806; 1907

1016-1724

31

1314

1263; 1438

1015-1737

0.95

   1745-2645(μg/kg lipid)

7

2222

2088; 2499

1995-2585

32

2163

2118; 2315

1753-2623

0.46

   > 2645(μg/kg lipid)

9

4248

3637;5231

2923-6528

29

3308

3267; 3903

2709-5640

0.02

Sum OCP (μg/kg lipid)

31(30)

2532

2224; 3581

250-7320

115(115)

2400

2130; 2678

128-8804

0.19

Sum DL-PCB (μg/kg lipid)

31(30)

149

141; 253

17.9-527

115(115)

198

189; 238

8.4-596.0

0.39

Sum PCB + sum OCP (μg/kg lipid)

31(30)

4424

3861; 6410

401-11849

115(115)

4206

3902; 4869

236-13300

0.35

Sum PCB + sum OCP + sum PFSA + sum PFCA (ng/ml)

31(31)

81.0

83.1; 124

22.1-231.8

115(115)

59.4

66.6; 88.0

4.9-298.0

0.007

Metals

         

Se (μg/kg)

31(30)

216

195; 439

101-1877

115(115)

265

294; 405

86.6-1805

0.56

Cd (μg/kg)

31(30)

0.9

0.6; 1.1

0.0-2.7

115(111)

1.03

1.11; 1.51

0.0-6.5

0.09

Hg (μg/kg)

31(30)

16.9

14.4; 24.6

1.54-61.7

115(115)

14.6

15.3; 23.8

0.4-194.0

0.30

Pb (μg/kg)

31(30)

42.7

37.1; 60.4

10.8-134

115(115)

53.2

60.6; 86.6

2.1-499.0

0.23

Zn (μg/kg)

31(30)

5643

5360; 6270

3013-8583

115(89)

4879

4754; 5301

2431-10822

0.003

  1. N: total number of subjects, n: number of subjects having information for the corresponding parameters.
  2. CI: confidence interval. SumPFSA: sum of PFOS, PFHxS and PFOSA; sumPFCA: sum of PFHpA, PFOA, PFNA, PFDA, PFUnA, PFDoA and PFTrA; sum PCB: sum of PCB 99, 101,105,118,128,138,153,156,170,180,183,187; sumOCP: sum of p, p'-DDT, p, p'-DDE, β-HCH, aldrin, HCB, oxychlorodane, cis-nonachlor and trans-nonachlor. SumDL-PCB (dioxin-like PCB): sum of PCB 105, PCB 118, and PCB 156.
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Environmental Health

ISSN: 1476-069X