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Table 2 Serum levels of POPs and blood metals in breast cancer patients and controls

From: Perfluorinated compounds are related to breast cancer risk in greenlandic inuit: A case control study

  Cases Controls p value
  N (n) median 95% CI Min-max N (n) median 95% CI Min-max  
POPs          
PFOS(ng/ml) 31(31) 45.6 45.7; 69.3 11.6-124 115(98) 21.9 31.1; 46.0 1.5-172 <0.0001
PFOA(ng/ml) 31(31) 2.5 2.2; 3.4 0.2-7.2 115(98) 1.6 2.11; 2.9 0.2-7. 6 0.04
Sum PFSA(ng/ml) 31(31) 48.2 49.6; 74.6 13.2-133 115(98) 24.6 33.7; 49.7 2.0-184 <0.0001
Sum PFCA(ng/ml) 31(31) 8.0 7.9; 11.9 3.3-21.4 115(98) 5.2 6.4; 9.2 1.0-28.1 0.001
Sum PCB(μg/kg lipid) 31(30) 2049 1596; 2870 150.5-6528 115(115) 1867 1759; 2203 92.7-5640 0.69
   < 920 (μg/kg lipid) 10 548 386; 734 151-857 23 451 379; 581 92.7-893 0.41
   920-1745(μg/kg lipid) 4 1343 806; 1907 1016-1724 31 1314 1263; 1438 1015-1737 0.95
   1745-2645(μg/kg lipid) 7 2222 2088; 2499 1995-2585 32 2163 2118; 2315 1753-2623 0.46
   > 2645(μg/kg lipid) 9 4248 3637;5231 2923-6528 29 3308 3267; 3903 2709-5640 0.02
Sum OCP (μg/kg lipid) 31(30) 2532 2224; 3581 250-7320 115(115) 2400 2130; 2678 128-8804 0.19
Sum DL-PCB (μg/kg lipid) 31(30) 149 141; 253 17.9-527 115(115) 198 189; 238 8.4-596.0 0.39
Sum PCB + sum OCP (μg/kg lipid) 31(30) 4424 3861; 6410 401-11849 115(115) 4206 3902; 4869 236-13300 0.35
Sum PCB + sum OCP + sum PFSA + sum PFCA (ng/ml) 31(31) 81.0 83.1; 124 22.1-231.8 115(115) 59.4 66.6; 88.0 4.9-298.0 0.007
Metals          
Se (μg/kg) 31(30) 216 195; 439 101-1877 115(115) 265 294; 405 86.6-1805 0.56
Cd (μg/kg) 31(30) 0.9 0.6; 1.1 0.0-2.7 115(111) 1.03 1.11; 1.51 0.0-6.5 0.09
Hg (μg/kg) 31(30) 16.9 14.4; 24.6 1.54-61.7 115(115) 14.6 15.3; 23.8 0.4-194.0 0.30
Pb (μg/kg) 31(30) 42.7 37.1; 60.4 10.8-134 115(115) 53.2 60.6; 86.6 2.1-499.0 0.23
Zn (μg/kg) 31(30) 5643 5360; 6270 3013-8583 115(89) 4879 4754; 5301 2431-10822 0.003
  1. N: total number of subjects, n: number of subjects having information for the corresponding parameters.
  2. CI: confidence interval. SumPFSA: sum of PFOS, PFHxS and PFOSA; sumPFCA: sum of PFHpA, PFOA, PFNA, PFDA, PFUnA, PFDoA and PFTrA; sum PCB: sum of PCB 99, 101,105,118,128,138,153,156,170,180,183,187; sumOCP: sum of p, p'-DDT, p, p'-DDE, β-HCH, aldrin, HCB, oxychlorodane, cis-nonachlor and trans-nonachlor. SumDL-PCB (dioxin-like PCB): sum of PCB 105, PCB 118, and PCB 156.