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Table 4 Adjusted hazard ratios (HR) of the association between nitrogen dioxide (NO 2 ) estimated from the 1995/96 and the 2007 LUR models and natural mortality. Rome 2001-2006

From: Nitrogen dioxide levels estimated from land use regression models several years apart and association with mortality in a large cohort study

  1995/96 LUR model 2007 LUR model
Population HR 95%CI Population HR 95%CI
Quintiles of NO2
1 136,842 1.00     136,841 1.00    
2 136,840 1.04 1.01 - 1.07 136,842 1.06 1.03 - 1.09
3 136,885 1.08 1.05 - 1.11 136,846 1.08 1.04 - 1.11
4 136,829 1.08 1.04 - 1.11 136,843 1.09 1.06 - 1.13
5 136,808 1.10 1.06 - 1.13 136,832 1.11 1.07 - 1.14
p-trend§   <0.001      <0.001    
Categories of NO2
<=35 μg/m3 44,357 1.00     103,836 1.00    
35-45 μg/m3 217,880 1.05 1.01 - 1.10 246,148 1.07 1.04 - 1.10
45-50 μg/m3 259,318 1.10 1.05 - 1.14 181,160 1.10 1.07 - 1.14
>50 μg/m3 162,649 1.13 1.08 - 1.18 153,060 1.12 1.08 - 1.16
p-trend§   <0.001      <0.001    
Effect per linear increase in NO2
per 10 μg/m3   1.06 1.04 - 1.08   1.04 1.03 - 1.05
per IQ range*   1.04 1.03 - 1.06   1.04 1.03 - 1.06
  1. HR, Hazard Ratios, adjusted for age, sex, marital status, place of birth, education, occupation, and area-based socioeconomic position.
  2. * The IQ ranges are 7.28 μg/m3 and 10.37 μg/m3, in 1995/96 and in 2007, respectively.
  3. § Wald test.