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Table 2 Mortality rate ratios associated with time-weighted average concentration of NO 2 from 1971 onwards at residential addresses

From: Traffic air pollution and mortality from cardiovascular disease and all causes: a Danish cohort study

   Mortality rate ratioa(95% CI)
Mortality (ICD-10 codes) Ndeaths Model with adjustment for sex and ageb Model with further adjustment for various variablesc Model with further adjustment for noised
All causes (except external, S-Z) 5534 1.52 (1.42-1.62) 1.18 (1.10-1.26) 1.13 (1.04-1.23)
Cardiovascular (I00-99) 1285 1.71 (1.50-1.94) 1.33 (1.16-1.54) 1.26 (1.06-1.51)
Ischemic heart disease (I20-25) 548 1.48 (1.21-1.82) 1.23 (0.99-1.54) 1.12 (0.85-1.47)
Cardiac rhythm disturbances (I44 + I47-49) 25 2.32 (0.95-5.67) 1.41 (0.50-3.94) 1.01 (0.28-3.65)
Heart failure (I50) 44 1.89 (0.94-3.80) 1.14 (0.52-2.51) 0.94 (0.35-2.53)
Cerebrovascular disease (I60-69) 292 1.40 (1.06-1.86) 1.13 (0.83-1.53) 1.11 (0.78-1.63)
Other cardiovascular disease 376 2.46 (1.96-2.09) 1.80 (1.41-2.32) 1.71 (1.25-2.37)
  1. Results based on 677 761 person-years at risk for 52 061 cohort participants from baseline (1993-1997) through 2009.
  2. aGiven per doubling of the NO2 concentration.
  3. bAdjusted for sex and age (age was the time scale in the Cox models).
  4. c Adjusted for sex, age (age was the time scale), calendar year, employment status, school attendance, occupation with potential exposure to smoke and fumes, smoking status, smoking intensity, smoking duration, environmental tobacco smoke, alcohol, fat, fish, fruit and vegetables, fiber, folate, body mass index, waist circumference, physical activity with sport, hormone replacement therapy, average gross income of municipality of residence in 1995. The Cox model stratified for marital status.
  5. dAs previous model with further adjustment for noise at the baseline address.