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Table 4 Results of multiple linear regression analysis of the associations between natural log transformed serum concentrations of groups of PCB congeners differing by the number of ortho- substituted chlorines and the various lipid fractions (n = 575)

From: Analysis of the effects of exposure to polychlorinated biphenyls and chlorinated pesticides on serum lipid levels in residents of Anniston, Alabama

  Mono-ortho Di-ortho Tri-/Tetra-ortho
  Model 1 Model 2 Model 1 Model 2 Model 1 Model 2
Total lipids β 0.04 −0.05 0.05 −0.09 0.06 0.12
p-value 0.0005 0.0814 <0.0001 0.0433 <0.0001 <0.0001
SP R22 0.0193 0.0040 0.0245 0.0053 0.0391 0.0209
Total Cholesterol β 0.03 −0.02 0.03 −0.08 0.04 0.09
p-value 0.0262 0.5254 0.0169 0.0846 0.0013 0.0047
SP R22 0.0081 0.0001 0.0094 0.0044 0.0169 0.0120
HDL cholesterol β 0.01 0.08 −0.00 −0.05 −0.00 −0.02
p-value 0.4722 0.0297 0.9741 0.4145 0.8036 0.6888
SP R22 0.0008 0.0072 0.0000 0.0010 0.0001 0.0010
LDL cholesterol β 0.02 −0.03 0.02 −0.09 0.04 0.11
p-value 0.2997 0.4565 0.1728 0.2056 0.0285 0.0133
SP R22 0.0018 0.0009 0.0032 0.0026 0.0082 0.0099
Triglycerides β 0.08 −0.16 0.09 −0.20 0.12 0.31
p-value 0.0117 0.0219 0.0018 0.0754 <0.0001 <0.0001
  SP R22 0.0099 0.0069 0.0152 0.0042 0.0279 0.0211
  1. Model 1: The estimates are adjusted for age (as well as age quadratic), race, gender, BMI, alcohol consumption, smoking and exercising status, but not adjusted for the two remaining PCB groups and chlorinated pesticides.
  2. Model 2: The estimates are adjusted for age (as well as age quadratic), race, gender, BMI, alcohol consumption, smoking and exercising status, and adjusted for the remaining two PCB groups and chlorinated pesticides.
  3. SP R22 – Type II semi-partial R2.