Within-person reproducibility of urinary bisphenol A and phthalate metabolites over a 1 to 3 year period among women in the Nurses’ Health Studies: a prospective cohort study

Table 1 Parameters of phthalate metabolites and phthalic acid for orbitrap mass spectrometry quantification

Compound name	Ionization mode	m/z	t_R(minutes)	LOD (ng/mL)
Monoethyl phthalate (MEP)	-ESI	193.05008	6.9	2
Mono-n-butyl phthalate (MnBP)	-ESI	221.08138	10.8	0.4
Monoisobutyl phthalate (MiBP)	-ESI	221.08138	10.7	0.3
Monobenzyl phthalate (MBzP)	-ESI	255.06573	11.4	0.1
Mono-2-ethylhexyl phthalate (MEHP)	-ESI	277.14398	12.8	0.5
Mono-(2-ethyl-5-hydroxyhexyl) phthalate (MEHHP)	-ESI	293.13890	10.5	0.1
Mono-(2-ethyl-5-oxohexyl) phthalate (MEOHP)	-ESI	291.12325	10.8	0.2
Mono-(2-ethyl-5-carboxy-pentyl) phthalate (MECPP)	-ESI	307.11816	10.6	0.2
Phthalic acid (PA)	-ESI	165.01858	2.63	0.1
Internal standards
¹³C₄- MEP	-ESI	197.06350	6.9
¹³C₄- MnBP	-ESI	225.09480	10.8
¹³C₄- MBzP	-ESI	259.07915	11.4
¹³C₄- MEHP	-ESI	281.15740	12.8
¹³C₄- MEOHP	-ESI	295.13666	10.8
PA-d₄	-ESI	169.04398	2.63

Abbreviations: --ESI negative electrospray ionization, LOD limit of detection, m/z mass-to-charge ratio, t _R retention time.

ISSN: 1476-069X