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Table 2 Regression models comparing hsCRP and IL-6 with distance from the highway

From: Highway proximity associated with cardiovascular disease risk: the influence of individual-level confounders and exposure misclassification

Highway distance Unadjusted model Exposure adjusted Adjusted model
(N = 260) (N = 252) (N = 225)
hsCRP %Diff 95%CI %Diff 95%CI %Diff 95%CI
Adj. R2 = 0.05 Adj. R2 = 0.14 Adj R2 = 0.38
0-50 m 67% (-8%,197%) 99% (12%,254%) 43% (-16%,141%)
50-150 m -15% (-48%,38%) -24% (-53%,22%) 7% (-39%,45%)
150-250 m 75% (9%,180%) 70% (7%,169%) 54% (-2%, 142%)
250-450 m 31% (-20%,116%) 29% (-27%,107%) 49% (-4%,131%)
≥1000 m ref ref ref    
IL-6 Adj. R 2  = 0.04 Adj. R 2  = 0.17 Adj R 2  = 0.29
0-50 m 51% (4%,119%) 72% (20%,146%) 49% (6%,110%)
50-150 m 28% (-6%,75%) 29% (-4%,73%) 41% (6%,86%)
150-250 m 54% (13%,108%) 43% (7%,90%) 18% (-11%, 57%)
250-450 m 46% (-5%,101%) 50% (11%,101%) 42% (6%,89%)
≥1000 m ref ref ref    
  1. Values represent percent difference between distance category and urban background population.
  2. Exposure adjusted models.
  3. hsCRP adjusted for time spent at home, windows opened in winter and summer, smoking pack years and driving on highway.
  4. IL 6 adjusted for time spent at home, windows opened in winter, work combustion exposures and air conditioner type.
  5. Fully adjusted models.
  6. hsCRP adjusted for age, smoking status, gender, income, BMI, born in the USA, vigorous physical activity, travel on highway, cooked with oil, non-workday time spent inside home, insulin medication, statin medication, heart attack.
  7. IL6 adjusted for age, gender, smoking status, BMI, workday time spent at home, windows opened in winter and air conditioner type.