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Table 6 Associations between quartiles of arsenic exposure and odds of self-reported symptoms during pregnancy in a subpopulation of women who did not report taking prescription or herbal medication during pregnancy (N = 1,166)

From: A prospective cohort study of the association between drinking water arsenic exposure and self-reported maternal health symptoms during pregnancy in Bangladesh

  Any symptom Cold/flu/infection Nausea/vomiting Abdominal cramping Headache
Water arsenic Crude OR aOR Crude OR aOR Crude OR aOR Crude OR aOR Crude OR aOR
(95% CI) (95% CI) (95% CI) (95% CI) (95% CI) (95% CI) (95% CI) (95% CI) (95% CI) (95% CI)
 Q4 (High) 2.84 (1.98–4.07) 2.33 (1.56–3.50) 0.79 (0.50–1.27) 0.79 (0.47–1.31) 2.17 (1.54–3.06) 1.86 (1.27–2.71) 2.49 (1.77–3.51) 1.80 (1.23–2.62) 1.14 (0.81–1.62) 1.09 (0.74–1.61)
 Q3 2.35 (1.66, 3.34) 2.06 (1.39–3.05) 0.96 (0.61–1.51) 0.91 (0.55–1.51) 1.78 (1.27–2.51) 1.55 (1.06–2.27) 1.96 (1.39–2.76) 1.45 (0.99–2.13) 0.97 (0.68–1.38) 0.91 (0.61–1.35)
 Q2 0.60 (0.44–0.83) 0.64 (0.45–0.92) 1.30 (0.86–1.98) 1.47 (0.94–2.32) 0.86 (0.61–1.22) 0.94 (0.64–1.37) 0.55 (0.37–0.80) 0.55 (0.37–0.83) 0.72 (0.50–1.02) 0.79 (0.54–1.16)
 Q1 (Low) 1.0 Ref 1.0 Ref 1.0 Ref 1.0 Ref 1.0 Ref 1.0 Ref 1.0 Ref 1.0 Ref 1.0 Ref 1.0 Ref
Test for trend <0.0001 <0.0001 0.13 0.39 <0.0001 0.0007 <0.0001 <0.0001 0.04 0.37
  1. Adjusted models include age, BMI, second-hand smoke exposure, maternal educational status, parity, anemia status, ferritin status, type of sanitation used at home, use of herbal remedy or medication, and household income. The average arsenic concentration and range for each quartile is: Q4 = 142.8 μg/L (32 μg/L – 1,400 μg/L); Q3 = 11.9 μg/L (2.1 μg/L – 31 μg/L); Q2 = 1.5 μg/L (0.9 μg/L – 2.0 μg/L); and Q1 = 0.7 μg/L (0.5 μg/L – 0.89 μg/L).
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