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Table 2 Bayesian and frequentist logistic regression results for preferred model comparing the log-odds of imidacloprid exposure during the prenatal period

From: Autism spectrum disorder, flea and tick medication, and adjustments for exposure misclassification: the CHARGE (CHildhood Autism Risks from Genetics and Environment) case–control study

 

OR

(95% CI) †

CLR‡

Frequentist

   

Crude

1.1

(0.71, 1.6)

2.3

Matching factors only

1.2

(0.79, 1.8)

2.3

Fully adjusted

1.3

(0.79, 2.2)

2.8

Occasional users vs. unexposed§

0.69

(0.27, 1.8)

6.6

Consistent users vs. unexposed§

2.0

(1.0, 3.9)

3.7

Bayesian

   

Naïve

1.3

(0.78, 2.2)

2.9

  1. † 95% CI – 95% Confidence (frequentist) or Credible (Bayesian) limits
  2. ‡ CLR – Confidence or Credible limit ratio = (upper 95% limit/lower 95% limit).
  3. All models were adjusted for child’s sex, regional center of birth, and age, maternal education, race/ethnicity, and parity and pet ownership during the prenatal period. Bayesian priors on regression coefficients and misclassification parameters are described in text.
  4. § Occasional users: reported imidacloprid use during some, but not all months of prenatal period; Consistent users: reported imidacloprid use during all months of prenatal period.
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Environmental Health

ISSN: 1476-069X