Table 2 Adjusted change in cortisol area under the curve (AUC) according to blood, tibia, and patella Pb concentrations in Mexico City women (2007–2011)
Pb biomarker/quantile | N | GM salivary cortisol AUC (nmol-hours) | % Difference in cortisol AUC nmol-hours (95% CI) |
|---|---|---|---|
Blood Pb 1 | Â | Â | Â |
Quintile 1 (0- < 1.8 µg/dL) | 185 | 82.0 | Ref |
Quintile 2 (1.8- < 2.4 µg/dL) | 183 | 88.6 | 8 (−1, 18) |
Quintile 3 (2.4- < 3.4 µg/dL) | 184 | 89.8 | 9 (0, 19) |
Quintile 4 (3.4- < 5.1 µg/dL) | 182 | 88.8 | 8 (−1, 18) |
Quintile 5 (≥5.1 µg/dL) | 184 | 83.8 | 2 (−6, 12) |
Continuous, per 2.5 µg/dL | 918 |  | −1 (−4, 1) |
Tibia Pb 2 | Â | Â | Â |
Quantile 1 (<2 µg/g) | 266 | 87.8 | Ref |
Quantile 2 (2- < 4.3 µg/g) | 82 | 83.2 | −5 (−14, 5) |
Quantile 3 (4.3- < 6.7 µg/g) | 82 | 89.3 | 2 (−8, 13) |
Quantile 4 (6.7- < 11.1 µg/g) | 82 | 87.5 | 0 (−10, 10) |
Quantile 5 (≥11.1 µg/g) | 82 | 93.4 | 6 (−4, 18) |
Patella Pb 2 | Â | Â | Â |
Quantile 1 (<2 µg/g) | 241 | 86.6 | Ref |
Quantile 2 (2- < 4.5 µg/g) | 86 | 87.6 | 1 (−8, 12) |
Quantile 3 (4.5- < 7.8 µg/g) | 87 | 81.8 | −6 (−14, 4) |
Quantile 4 (7.8- < 12.7 µg/g) | 86 | 97.0 | 12 (1, 24) |
Quantile 5 (>12.7-43.2 µg/g) | 87 | 90.3 | 4 (−6, 16) |