Air pollution and lung function among susceptible adult subjects: a panel study

Lagorio, Susanna; Forastiere, Francesco; Pistelli, Riccardo; Iavarone, Ivano; Michelozzi, Paola; Fano, Valeria; Marconi, Achille; Ziemacki, Giovanni; Ostro, Bart D

doi:10.1186/1476-069X-5-11

Environmental Health

Table 4 Variations in respiratory function per unit increase of air pollutant concentrations in the three panels

From: Air pollution and lung function among susceptible adult subjects: a panel study

			PM_2.5			PM_10–2.5			PM₁₀			NO₂			CO			O₃
Pollutant increase			10 μg/m³			10 μg/m³			10 μg/m³			10 μg/m³			1 mg/m³			10 μg/m³
Panel	Outcome	Time	β *	SE (β)	p	β	SE (β)	p	β	SE (β)	p	β	SE (β)	p	β	SE (β)	p	β	SE (β)	p
COPD		24 h ^†	-0.80	0.36	0.027	-1.32	1.06	0.210	-0.66	0.30	0.027	-0.72	0.49	0.139	-0.14	0.15	0.353	0.01	0.57	0.983
	FVC (%)	48 h ^‡	-0.89	0.41	0.031	-1.46	1.31	0.265	-0.75	0.35	0.032	-0.43	0.58	0.463	-0.13	0.18	0.497	0.18	0.65	0.783
		72 h ^§	-1.10	0.55	0.044	-1.38	1.53	0.367	-0.94	0.47	0.045	-0.10	0.70	0.886	0.15	0.23	0.508	-0.03	0.86	0.977
		24 h ^†	-0.47	0.33	0.149	-0.59	0.95	0.532	-0.37	0.27	0.167	-1.16	0.41	0.005	-0.05	0.13	0.725	-0.20	0.50	0.687
	FEV ₁ (%)	48 h ^‡	-0.69	0.37	0.061	-1.01	1.19	0.396	-0.58	0.31	0.067	-1.38	0.49	0.005	-0.12	0.16	0.467	0.31	0.56	0.578
		72 h ^§	-1.06	0.50	0.032	-0.90	1.42	0.524	-0.87	0.43	0.040	-0.94	0.60	0.117	-0.03	0.20	0.900	0.68	0.74	0.363
Asthma		24 h ^†	-0.14	0.29	0.617	-0.17	0.75	0.822	-0.12	0.24	0.621	-0.53	0.31	0.081	0.02	0.12	0.842	-0.33	0.41	0.416
	FVC (%)	48 h ^‡	-0.07	0.33	0.825	-0.36	0.91	0.695	-0.09	0.29	0.750	-0.59	0.32	0.065	-0.001	0.13	0.995	0.02	0.42	0.957
		72 h ^§	-0.06	0.39	0.886	-0.24	1.07	0.824	-0.08	0.36	0.836	-0.54	0.37	0.149	-0.06	0.16	0.700	0.14	0.50	0.782
		24 h ^†	-0.30	0.34	0.372	-0.67	0.89	0.448	-0.28	0.28	0.317	-1.10	0.35	0.002	-0.05	0.14	0.704	-0.41	0.50	0.421
	FEV ₁ (%)	48 h ^‡	-0.36	0.39	0.347	-1.19	1.07	0.265	-0.40	0.34	0.239	-1.28	0.37	0.001	-0.16	0.15	0.292	-0.01	0.51	0.983
		72 h ^§	-0.40	0.46	0.384	-0.51	1.26	0.689	-0.40	0.43	0.351	-1.17	0.44	0.007	-0.28	0.18	0.126	0.46	0.60	0.449
IHD		24 h ^†	0.37	0.26	0.164	0.37	0.73	0.617	0.28	0.22	0.198	0.15	0.29	0.612	0.176	0.101	0.081	0.58	0.33	0.077
	FVC (%)	48 h ^‡	0.51	0.29	0.082	-0.25	0.88	0.779	0.35	0.25	0.160	-0.06	0.37	0.868	0.132	0.120	0.271	0.36	0.42	0.392
		72 h ^§	0.73	0.40	0.069	0.67	1.04	0.519	0.59	0.34	0.079	0.36	0.47	0.440	0.132	0.165	0.425	0.08	0.60	0.898
		24 h ^†	0.43	0.33	0.192	0.25	0.86	0.770	0.32	0.27	0.240	-0.24	0.36	0.513	0.204	0.120	0.088	0.57	0.39	0.144
	FEV ₁ (%)	48 h ^‡	0.55	0.34	0.106	-0.23	1.02	0.818	0.38	0.29	0.193	0.00	0.44	0.994	0.114	0.142	0.420	0.53	0.50	0.288
		72 h ^§	0.66	0.47	0.157	0.18	1.19	0.877	0.49	0.39	0.214	0.21	0.56	0.710	0.159	0.194	0.412	0.65	0.70	0.354

*Regression coefficient from GEE models for panel data controlling for repeated individual observations, temperature, relative humidity, and day of the week (COPD and IHD panels) or β-2 stimulant inhalation (asthma panel), representing the change in lung function index (% of predicted) per unit increase of pollutant concentration.
^†Concentration during the previous 24 hours.
^‡Average concentration over the previous 48 hours.
^§Average concentration over the previous 72 h.

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ISSN: 1476-069X

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