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Table 3 Observed deaths and SMRs for selected causes of deatha, stratified by duration of employmentb

From: Update: cohort mortality study of workers highly exposed to polychlorinated biphenyls (PCBs) during the manufacture of electrical capacitors, 1940-1998

Cause of death Duration of employment Trend p-valuec
  < 5 years 5 – 9 years ≥10 years  
  O SMR 95% CI O SMR 95% CI O SMR 95% CI  
All deaths 279 1.07 0.95 – 1.21 148 1.07 0.90 – 1.25 371 0.90 0.81 – 1.00 0.018
All cancers 73 1.08 0.84 – 1.35 41 1.06 0.76 – 1.44 104 0.95 0.78 – 1.15 0.38
MN of intestine, excluding rectum 7 1.16 0.47 – 2.39 6 1.69 0.62 – 3.67 14 1.30 0.71 – 2.17 0.97
   Among women 7 1.94 0.78 – 4.00 6 2.46 0.90 – 5.36 11 1.66 0.83 – 2.97 0.61
MN of rectum 0    2 2.75 0.33 – 9.93 4 1.91 0.52 – 4.89 ---
MN of biliary passages, liver and gall bladder 4 2.49 0.68 – 6.38 2 2.16 0.26 – 7.80 5 1.86 0.60 – 4.34 0.66
MN of breast 5 0.61 0.20 – 1.43 2 0.39 0.05 – 1.40 8 0.67 0.29 – 1.32 0.74
MN of prostate 1 0.64 0.02 – 3.55 0    6 1.58 0.58 – 3.44 ---
Neoplasms of lymphatic and hematopoietic tissue 9 1.33 0.61 – 2.52 3 0.84 0.17 – 2.47 10 1.02 0.49 – 1.88 0.65
   Non-Hodgkin's lymphomad 4 1.63 0.44 – 4.16 3 2.32 0.48 – 6.78 3 0.78 0.16 – 2.27 0.25
   Myelomad 2 2.08 0.25 – 7.50 0    5 2.80 0.91 – 6.54 ---
Other diseases of the nervous system and sense organs           
   Underlying cause of death 1 0.27 0.01 – 1.48 3 1.56 0.32 – 4.56 12 1.95 1.01–3.40 0.039
   Multiple cause of deathd 6 0.51 0.19 – 1.10 4 0.65 0.18 – 1.66 28 1.37 0.91–1.98 0.011
Ischemic heart disease 69 1.22 0.95 – 1.54 47 1.44 1.06 – 1.91 108 0.97 0.80 – 1.18 0.057
  1. Abbreviations: O: observed number of deaths; SMR: standardized mortality ratio; CI: confidence interval; MN: malignant neoplasm.
  2. a A priori causes of death with sufficient numbers to stratify plus significant new findings.
  3. b Person-years at risk and observed deaths among 2572 workers in jobs with potential for the highest, most direct exposure to PCBs began accruing in 1940.
  4. c Trend test performed for causes of death with 10 or more observed deaths.
  5. d Person-years at risk and observed deaths began accruing in 1960 for non-Hodgkin's lymphoma, myeloma, and multiple cause of death from other diseases of the nervous system and sense organs due to rate file restrictions.