|
Liver (n = 59)
| | | | | |
|
Multifocally mononuclear cell infiltrations
|
89 (53)
|
11 (6)
|
-
|
-
|
n.s.
|
|
Portal mononuclear cell infiltrations
|
85 (50)
|
8 (5)
|
7 (4)
|
-
|
n.s.
|
|
Lipid granulomas
|
37 (22)
|
36 (21)
|
22 (13)
|
5 (3)
|
n.s.
|
|
Hepatocytic steatosis
|
-
|
24 (14)
|
24 (14)
|
52 (31)
|
n.s.
|
|
Ito cell lipid accumulation
|
36 (21)
|
14 (8)
|
19 (11)
|
31 (19)
|
** (7.8)
|
|
Bile duct proliferation with fibrosis
|
92 (54)
|
8 (5)
|
-
|
-
|
*** (15.6)
|
|
Kidney (n = 57)
| | | | | |
|
Glomerular diffuse capillary wall thickening
|
72 (41)
|
25 (14)
|
3 (2)
|
-
|
*** (8)
|
|
Glomerular mesangial deposits/sclerosis
|
22 (13)
|
39 (22)
|
39 (22)
|
-
|
* (5.6)
|
|
Interstitial fibrosis
|
75 (42)
|
12 (7)
|
13 (8)
|
-
|
*** (49.8)
|
|
Tubular epithelial cell hyperplasia
|
75 (42)
|
12 (7)
|
13 (8)
|
-
|
** (6.7)
|
|
Tubular hyalinization/atrophy/dilatation/necrosis
|
61 (35)
|
12 (7)
|
27 (15)
|
-
|
*** (30.8)
|
|
Tubular medullar hyaline casts
|
84 (48)
|
13 (8)
|
3 (1)
|
-
|
* (6.6)
|
|
Mononuclear cell infiltrations
|
39 (22)
|
42 (24)
|
19 (11)
|
-
|
n.s.
|
