|  | Exposure | ||||
---|---|---|---|---|---|---|
Unit of observation | Outcome1 | Cohort affiliation | Childhood exposure2 | Fish consumption | CB-1533 | p,p'-DDE4 |
Man | Sperm motility | - | - | - | ↓ [16] | ↓ [16] |
 | Sperm concentration | - | - | - | 0 [16] | 0 [16] |
 | Semen volume | - | - | - | 0 [16] | 0 [16] |
 | Total sperm count | - | - | - | 0 [16] | 0 [16] |
 | Sperm chromatin integrity | - | - | - | ↓ [20] | (↓) [20] |
 | Y:X chromosome ratio | - | - | - | ↓ [21] | ↓ [21] |
 | Seminal levels of markers of epididymal and accessory sex gland function | - | - | - | 0 [19] | 0 [19] |
 | Hormone parameters | - | - | - | 0 [16] | 0 [16] |
Woman | Age at menarche | 0 [38] | ↓ [38] | - | - | - |
 | Menstrual cycle length | ↓ [91] | 0 [91] | (↓) [91] | 0 [91] | - |
 | Miscarriages and stillbirths | NC [17, 25, 40] | 0 [25, 40] | 0 [25] | NC [26, 40] | - |
Couple | Time to pregnancy | NC [24, 25] | 0 [24, 25] | 0 [24, 25] | 0 [26, 33] | - |
Infant/child | Birth weight | ↓ [14, 17] | ↓ [41] | ↓ [41] | ↓ [31] | - |
 | Birth length | 0 [14, 17] | - | - | - | - |
 | Head circumference | ↓ [14, 17] | - | - | - | - |
 | Gender ratio | NC [14, 17] | - | - | - | - |
 | Malformations | 0 [17, 43] | - | - | - | - |