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Table 6 Differential gene expressions in various tissues. a

From: Feeding mice with diets containing mercury-contaminated fish flesh from French Guiana: a model for the mercurial intoxication of the Wayana Amerindians

 

Hippocampus

Liver

Kidneys

Muscles

Food (ng Hg/g)

5.4

62

520

5.4

62

520

5.4

62

520

5.4

62

CoxI

=

=

=

4

16

16

=

32

=

=

=

Sod2

=

=

16

=

2

2

=

=

1/4

=

=

Sod3

=

2

=

=

4

4

=

8

=

=

4

Mt1

=

=

8

=

=

=

=

=

=

=

=

Mt2

=

2

4

4

4

4

=

=

=

=

=

Gsta4

=

=

=

=

2

2

=

=

=

=

=

Bax

=

=

16

=

=

=

=

16

=

=

=

Fos

=

2

4

=

=

=

2

2

=

=

=

  1. a Differential gene expressions after 1 month feeding with fish-containing diets. Three independent determinations per sample were carried out. The numbers are indicating the significant differential gene expressions. =: identical to control.
  2. Bax: Bcl2-associated X protein; Cox I: cytochrome c oxidase subunit I; fos: FBJ osteosarcoma oncogene; Gsta4: glutathione S-transferase, alpha 4; Mt1: metallothionein isoform 1; Mt2: metallothionein isoform 2; Sod2: mitochondrial superoxide dismutase; Sod3: extracellular superoxide dismutase.