| |
Exposure to pesticides (β ± SEM)
|
P
|
P* adjusted
|
Time of exposure to pesticides (β ± SEM)
|
P
|
P* adjusted
|
|---|
|
Time of liquefaction minutes
|
-1.53 ± 1.74
|
0.38
|
0.75
|
0.11 ± 0.31
|
0.71
|
0.93
|
|
Seminal Volume mL
|
-0.72 ± 0.31
|
0.02
|
0.12
|
-0.09 ± 0.06
|
0.15
|
0.28
|
|
pH
|
0.29 ± 0.09
|
0.002
|
0.002
|
0.03 ± 0.02
|
0.07
|
0.001
|
|
Log Corrected fructose
|
-0.17 ± 0.09
|
0.06
|
0.15
|
-0.04 ± 0.01
|
0.01
|
0.53
|
|
Log Seminal zinc
|
-0.05 ± 0.09
|
0.58
|
0.30
|
-0.02 ± 0.02
|
0.26
|
0.38
|
|
Log sperms/mL
|
-0.14 ± 0.12
|
0.25
|
0.84
|
-0.02 ± 0.02
|
0.44
|
0.89
|
|
Log sperms/ejaculum
|
-0.24 ± 0.15
|
0.10
|
0.60
|
-0.04 ± 0.03
|
0.15
|
0.80
|
|
Sperm Vitality %
|
2.07 ± 1.79
|
0.25
|
0.06
|
-0.21 ± 0.32
|
0.51
|
0.13
|
|
Log motility grade 3 (%)
|
-0.02 ± 0.09
|
0.78
|
0.71
|
-0.02 ± 0.02
|
0.14
|
0.82
|
|
Log motility grade 3 + 2 (%)
|
-0.05 ± 0.05
|
0.32
|
1.00
|
-0.02 ± 0.01
|
0.13
|
0.74
|
|
Sperm with normal morphology (%)
|
-7.65 ± 2.16
|
0.001
|
0.76
|
-1.04 ± 0.42
|
0.01
|
0.42
|
|
Immature sperm (%)
|
1.89 ± 1.48
|
0.21
|
1.00
|
0.17 ± 0.26
|
0.51
|
0.50
|
|
Log Seminal leucocytes
|
0.59 ± 0.09
|
0.00
|
1.00
|
0.02 ± 0.02
|
0.36
|
0.97
|
|
Serum testosterone (ng/mL)
|
-0.62 ± 0.41
|
0.13
|
0.69
|
-0.10 ± 0.07
|
0.16
|
0.99
|
|
Log Serum estradiol (pg/ml)
|
0.06 ± 0.07
|
0.43
|
0.26
|
0.03 ± 0.01
|
0.02
|
0.65
|
|
Log Serum FSH (mIU/mL)
|
0.17 ± 0.18
|
0.34
|
0.86
|
0.01 ± 0.03
|
0.72
|
1.00
|
|
Log Serum LH (mIU/mL)
|
-0.37 ± 0.21
|
0.07
|
0.97
|
-0.10 ± 0.03
|
0.01
|
0.99
|
|
Log T/E2 (ng/pg)
|
-0.11 ± 0.07
|
0.12
|
0.18
|
-0.04 ± 0.01
|
0.01
|
0.63
|
|
Log T/LH (ng/mIU)
|
0.32 ± 0.20
|
0.13
|
1.00
|
0.01 ± 0.03
|
0.01
|
0.85
|
- Regressions adjusted for age and alcohol consumption. Exposure to pesticide: 0 = non exposed; 1 = exposed. Ethylated metabolites of OPs: 0 = non detectable; 1 = over limit of detection. Time of exposure to pesticides (continuous variable). β ± SEM: Coefficient of regression ± Standard error of the mean. Data with non parametric behavior were log-transformed in order to performed linear regression analyses. *Holm adjustment.
- +Analyses were performed after controlling for urine levels of ethylated OP metabolites, respectively.
