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Table 2 Regression coefficients and probability values to determine the association between seminal parameters and exposure and time of exposure to ethylated OP metabolites.

From: Semen quality in Peruvian pesticide applicators: association between urinary organophosphate metabolites and semen parameters

 

Exposure to pesticides (β ± SEM)

P

P* adjusted

Time of exposure to pesticides (β ± SEM)

P

P* adjusted

Time of liquefaction minutes

-1.53 ± 1.74

0.38

0.75

0.11 ± 0.31

0.71

0.93

Seminal Volume mL

-0.72 ± 0.31

0.02

0.12

-0.09 ± 0.06

0.15

0.28

pH

0.29 ± 0.09

0.002

0.002

0.03 ± 0.02

0.07

0.001

Log Corrected fructose

-0.17 ± 0.09

0.06

0.15

-0.04 ± 0.01

0.01

0.53

Log Seminal zinc

-0.05 ± 0.09

0.58

0.30

-0.02 ± 0.02

0.26

0.38

Log sperms/mL

-0.14 ± 0.12

0.25

0.84

-0.02 ± 0.02

0.44

0.89

Log sperms/ejaculum

-0.24 ± 0.15

0.10

0.60

-0.04 ± 0.03

0.15

0.80

Sperm Vitality %

2.07 ± 1.79

0.25

0.06

-0.21 ± 0.32

0.51

0.13

Log motility grade 3 (%)

-0.02 ± 0.09

0.78

0.71

-0.02 ± 0.02

0.14

0.82

Log motility grade 3 + 2 (%)

-0.05 ± 0.05

0.32

1.00

-0.02 ± 0.01

0.13

0.74

Sperm with normal morphology (%)

-7.65 ± 2.16

0.001

0.76

-1.04 ± 0.42

0.01

0.42

Immature sperm (%)

1.89 ± 1.48

0.21

1.00

0.17 ± 0.26

0.51

0.50

Log Seminal leucocytes

0.59 ± 0.09

0.00

1.00

0.02 ± 0.02

0.36

0.97

Serum testosterone (ng/mL)

-0.62 ± 0.41

0.13

0.69

-0.10 ± 0.07

0.16

0.99

Log Serum estradiol (pg/ml)

0.06 ± 0.07

0.43

0.26

0.03 ± 0.01

0.02

0.65

Log Serum FSH (mIU/mL)

0.17 ± 0.18

0.34

0.86

0.01 ± 0.03

0.72

1.00

Log Serum LH (mIU/mL)

-0.37 ± 0.21

0.07

0.97

-0.10 ± 0.03

0.01

0.99

Log T/E2 (ng/pg)

-0.11 ± 0.07

0.12

0.18

-0.04 ± 0.01

0.01

0.63

Log T/LH (ng/mIU)

0.32 ± 0.20

0.13

1.00

0.01 ± 0.03

0.01

0.85

  1. Regressions adjusted for age and alcohol consumption. Exposure to pesticide: 0 = non exposed; 1 = exposed. Ethylated metabolites of OPs: 0 = non detectable; 1 = over limit of detection. Time of exposure to pesticides (continuous variable). β ± SEM: Coefficient of regression ± Standard error of the mean. Data with non parametric behavior were log-transformed in order to performed linear regression analyses. *Holm adjustment.
  2. +Analyses were performed after controlling for urine levels of ethylated OP metabolites, respectively.