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Table 4 Results of cancer incidence analyses in the Seveso population*, 1977-96, by time since the accident.

From: Cancer incidence in the population exposed to dioxin after the "Seveso accident": twenty years of follow-up

Cancer sites Zone   Years since the accident
    0-4 5-9 10-14 15 +
All cancers A N 8 8 9 19
   RR 1.06 0.84 0.83 1.27
   95% CI 0.53-2.12 0.42-1.68 0.43-1.60 0.81-2.00
  B N 55 51 72 92
   RR 1.13 0.84 1.05 1.02
   95% CI 0.87-1.48 0.63-1.10 0.83-1.32 0.83-1.26
  R N 339 411 455 603
   RR 0.94 0.93 0.96 0.99
   95% CI 0.84-1.06 0.84-1.03 0.87-1.06 0.90-1.07
Lung cancer A N 1 1 1 4
   RR 0.84 0.73 0.57 2.04
   95% CI 0.12-5.96 0.10-5.19 0.08-4.08 0.76-5.47
  B N 8 8 9 12
   RR 1.02 0.89 0.86 1.09
   95% CI 0.50-2.05 0.44-1.79 0.44-1.66 0.61-1.93
  R N 37 70 83 90
   RR 0.66 1.09 1.15 1.20
   95% CI 0.47-0.92 0.84-1.41 0.91-1.46 0.95-1.50
Lymphatic and hematopoietic tissue cancer A N - - 1 3
   RR    1.39 2.96
   95% CI    0.20-9.96 0.95-9.22
  B N 9 5 9 6
   RR 2.39 1.33 1.92 0.95
   95% CI 1.22-4.69 0.55-3.25 0.98-3.75 0.42-2.12
  R N 20 27 32 42
   RR 0.75 1.03 1.01 1.00
   95% CI 0.47-1.20 0.68-1.55 0.70-1.48 0.72-1.38
Non-Hodgkin's lymphoma A N - - - 1
   RR     1.97
   95% CI     0.27-14.07
  B N 2 2 5 3
   RR 1.75 1.37 2.30 0.94
   95% CI 0.43-7.20 0.34-5.62 0.93-5.66 0.30-2.96
  R N 5 15 8 21
   RR 0.61 1.44 0.54 0.99
   95% CI 0.24-1.53 0.82-2.53 0.26-1.12 0.62-1.58
Leukemia A N - - 1 1
   RR    5.11 3.26
   95% CI    0.71-37.07 0.45-23.44
  B N 3 1 2 2
   RR 1.90 0.85 1.55 1.05
   95% CI 0.60-6.05 0.12-6.15 0.38-6.37 0.26-4.29
  R N 6 8 14 3
   RR 0.55 0.98 1.60 0.24
   95% CI 0.24-1.26 0.46-2.07 0.88-2.90 0.07-0.75
Multiple myeloma A N - - - 1
   RR     8.35
   95% CI     1.14-61.31
  B N 2 2 2 -
   RR 3.56 4.76 4.47  
   95% CI 0.85-15.00 1.11-20.38 1.04-19.20  
  R N 1 2 4 11
   RR 0.23 0.63 1.28 2.24
   95% CI 0.03-1.70 0.15-2.68 0.44-3.77 1.11-4.49
Breast cancer (females only) A N - 1 2 5
   RR   0.81 1.42 2.57
   95% CI   0.11-5.74 0.35-5.68 1.07-6.20
  B N 4 6 10 10
   RR 0.70 0.79 1.09 0.78
   95% CI 0.26-1.87 0.35-1.76 0.58-2.04 0.42-1.46
  R N 48 59 55 87
   RR 1.10 1.07 0.87 1.01
   95% CI 0.81-1.49 0.81-1.41 0.66-1.15 0.81-1.27
  1. *Subjects aged < 75 years, resident in the area at the accident time.
  2. ICD-9: International Classification of Diseases, Ninth Revision; N: number of cases; RR: rate ratios calculated with Poisson regression, adjusted for gender and age category; 95% CI: 95% confidence interval.