Table 1 Toxicity of Ag and CeO2 particles in in vitro experiments. The table lists the LC50 for Ag and CeO2 particles in in vitro experiments (C3A and primary trout hepatocytes), and the lowest concentration at which significant toxicity was observed in acute exposures of D. magna neonates. For cell cultures, doses between 3 and 1000 μg/ml were used. For the D. magna exposures, doses between 0.01 and 10 μg/ml were used.
| Â | Ag nano | Ag bulk | CeO2 nano | CeO2 bulk |
|---|---|---|---|---|
D. magna neonates (96 h) | 60% mortality at 0.1 μg/ml | 80% mortality at 1 μg/ml | No mortality observed | No mortality observed |
C3A hepatocytes (24 h) | 50 μg/ml (31.25 μg/cm2) | 300 μg/ml (187.5 μg/cm2) | >1000 μg/ml (>625 μg/cm2) | >1000 μg/ml (>625 μg/cm2) |
Primary trout hepatocytes (24 h) | 1000 μg/ml (625 μg/cm2) | >1000 μg/ml (>625 μg/cm2) | >1000 μg/ml (>625 μg/cm2) | >1000 μg/ml (>625 μg/cm2) |