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Table 3 The % change in the levels of hs CRP, soluble VCAM-1, and soluble ICAM-1 for a 5°C decrease in ambient temperature

From: Associations between outdoor temperature and markers of inflammation: a cohort study

 

Original modela

Adjusted for BCb

Adjusted for O3 c

 

% Change

95% CI

% Change

95% CI

% Change

95% CI

hs C-reactive protein

      

Lag 0

8.02 *

1.93, 14.8

7.03 *

0.60, 13.9

9.39 *

2.97, 16.2

Lag 1

8.18 *

1.57, 15.2

10.0 *

3.09, 17.4

9.26 *

2.63, 16.6

1 week

10.2 *

0.51, 20.8

10.1

-0.12, 21.3

12.6 *

2.41, 23.8

2 weeks

16.7 *

4.05, 30.8

15.0 *

2.06, 29.6

19.2 *

6.11, 34.0

3 weeks

22.1 *

6.89, 39.6

19.7 *

4.12, 37.6

23.3 *

7.72, 41.0

4 weeks

24.9 *

7.36, 45.2

23.4 *

5.53, 44.2

26.3 *

8.50, 47.0

Soluble vascular cell adhesion molecule-1

     

Lag 0

-0.94

-2.68, 1.02

0.41

-1.66, 2.52

-0.48

-2.49, 1.57

Lag 1

0.77

-1.36, 2.94

1.57

-0.62, 3.82

0.63

-1.56, 2.88

1 week

1.44

-1.66, 4.64

2.49

-0.82, 5.91

0.64

-2.52, 3.91

2 weeks

3.80

-0.13, 7.89

4.96 *

0.18, 9.28

2.82

-1.15, 6.95

3 weeks

4.41

-0.19, 9.22

5.70 *

0.84, 10.8

3.71

-0.89, 8.53

4 weeks

6.60 *

1.31, 12.2

8.04 *

2.51, 13.9

5.83 *

0.56, 11.4

Soluble intercellular adhesion molecule-1

     

Lag 0

0.79

-0.51, 2.10

0.71

-0.68, 2.11

1.31

-0.01, 2.71

Lag 1

0.02

-1.39, 1.44

-0.08

-1.53, 1.39

0.32

-1.12, 1.79

1 week

0.31

-1.74, 2.40

0.91

-1.26, 3.13

0.22

-1.88, 2.36

2 weeks

1.82

-0.76, 4.47

2.95 *

0.23, 5.74

1.41

-1.21, 4.10

3 weeks

2.91

-0.12, 6.04

4.64 *

1.42, 7.92

2.59

-0.45, 5.72

4 weeks

4.52 *

1.05, 8.10

6.42 *

2.79, 10.2

4.23 *

0.76, 7.82

  1. * P-value < 0.05
  2. a Model adjusted for relative humidity, barometric pressure, season, time trend, weekday, age, smoking, use of any anti-hypertensive medication and statins, body mass index, hypertension, education, diabetes, alcohol use (≥ 2 drinks/day), and race
  3. b Model adjusted for black carbon, relative humidity, barometric pressure, season, time trend, weekday, age, smoking, use of any antihypertensive medication and statins, body mass index, hypertension, education, diabetes, alcohol use (≥ 2 drinks/day), and race
  4. c Model adjusted for ozone, relative humidity, barometric pressure, season, time trend, weekday, age, smoking, use of any antihypertensive medication and statins, body mass index, hypertension, education, diabetes, alcohol use (≥ 2 drinks/day), and race