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Table 2 Associations of product use and phthalate metabolite concentrations (ng/mL) among US reproductive-aged women, NHANES 2001-2004a

From: Vaginal douching and racial/ethnic disparities in phthalates exposures among reproductive-aged women: National Health and Nutrition Examination Survey 2001–2004

 

MEP

MnBP

 

Unadjusted (N = 739)

Adjusted (N = 731)

Unadjusted (N = 739)

Adjusted (N = 731)

 

% change

95 % CI

% change

95 % CI

% change

95 % CI

% change

95 % CI

Feminine hygiene product use in past month

Tamponb

−6.4

(−24.9, 16.6)

6.1

(−16.0, 35.5)

2.4

(−11.8, 18.9)

4.1

(−11.0, 21.9)

Sanitary napkinb

−7.6

(−21.5, 8.7)

−9.0

(−22.8, 7.2)

−3.2

(−17.6, 13.6)

−4.4

(−18.9, 12.7)

Vaginal doucheb

59.5*

(22.7, 107.2)

51.6*

(18.8, 93.6)

12.2

(−8.3, 37.3)

9.8

(−9.7, 33.6)

Feminine sprayb

79.7

(−2.6, 231.4)

63.2

(−12.4, 204.2)

26.4

(−15.0, 88.1)

20.7

(−21.0, 84.3)

Feminine powderb

64.9

(−16.4, 225.3)

49.4

(−23.9, 193.2)

23.7

(−25.7, 105.9)

16.6

(−32.1, 100.3)

Wipes/ Towelettesb

21.5

(−11.1, 65.9)

14.7

(−16.0, 56.7)

−6.5

(−25.8, 17.9)

−7.8

(−27.9, 17.9)

Other productsb

35.4

(−12.2, 108.7)

26.9

(−19.8, 100.8)

27.8

(−7.5, 76.7)

25.9

(−7.9, 72.1)

Average douching frequency in past 6 monthsb

Occasional (≤1 month)

40.5*

(6.1, 86.1)

33.6

(−0.3,79.2)

7.7

(−5.6, 22.8)

8.2

(−4.5, 22.6)

Frequent (≥2 month)

154.4**

(68.7, 283.6)

152.2**

(68.2, 278.3)

29.0

(−6.2, 77.3)

24.1

(−10.3, 71.8)

P-trend

 

<0.001

 

<0.001

 

0.094

 

0.145

  1. aMEP and MnBP concentrations were natural log transformed. All models were adjusted for urinary creatinine; adjusted models additionally controlled for age, race/ethnicity, BMI, and educational attainment
  2. bReference group is non-users; *p < 0.05; ** p < 0.001