Fig. 2From: Characterization of genome-wide H3K27ac profiles reveals a distinct PM2.5-associated histone modification signatureGlobal profiles of H3K27ac overlapped with promoters and enhancers. Global H3K27ac signal densities normalized by input were determined in a 20Â kb-window surrounding a the center of ENCODE-detected enhancers; and b the TSS of human RefSeq genes. The red curve represents the average H3K27ac signal density in the high-exposed group and the blue curve represents the average density in the low-exposed group. Both promoters and enhancers show global elevated H3K27ac modification levels in the individuals exposed to higher PM2.5 (red). TSS: transcription start siteBack to article page