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Table 3 Crude and adjusted ORs for male breast cancer by exposure status

From: Evaluation of contaminated drinking water and male breast cancer at Marine Corps Base Camp Lejeune, North Carolina: a case control study

Exposure Controls Cases OR (95 % CI) p-value aORa (95 % CI) p-value
# (%) # (%)
Ever stationed at Camp Lejeune
No 248 (66.5) 41 (57.7) 1.00 (ref.)   1.00 (ref.)  
Yes 125 (33.5) 30 (42.3) 1.45 (0.86-2.44) 0.16 1.14 (0.65-1.97) 0.65
Cumulative PCE
No exposure 357 (96.0) 67 (94.4) 1.00 (ref.)   1.00 (ref.)  
Low (>0- < 36 ppb-months) 7 (1.9) 2 (2.8) 1.52 (0.21-7.00) 0.59 1.05 (0.14-5.14) 0.91
High (≥36 ppb-months) 8 (2.2) 2 (2.8) 1.33 (0.19-5.91) 0.69 1.20 (0.16-5.89) 0.80
Cumulative TCE
No exposure 258 (69.4) 46 (64.8) 1.00 (ref.)   1.00 (ref.)  
Low (>0- <159 ppb-months) 57 (15.3) 13 (18.3) 1.28 (0.63-2.49) 0.48 1.06 (0.50-2.13) 0.86
High (≥159 ppb-months) 57 (15.3) 12 (16.9) 1.18 (0.57-2.34) 0.63 0.93 (0.43-1.90) 0.85
Cumulative benzene
No exposure 260 (69.9) 46 (64.8) 1.00 (ref.)   1.00 (ref.)  
Low (>0- < 3.6 ppb-months) 57 (15.3) 15 (21.1) 1.49 (0.76-2.82) 0.24 1.67 (0.82-3.30) 0.15
High (≥3.6 ppb-months) 55 (14.8) 10 (14.1) 1.03 (0.47-2.18) 0.92 0.57 (0.24-1.25) 0.17
Cumulative DCE
No exposure 356 (95.7) 67 (94.4) 1.00 (ref.)   1.00 (ref.)  
Low (>0- <472 ppb-months) 8 (2.2) 1 (1.4) 0.67 (0.03-4.25) 0.78 0.56 (0.02-3.83) 0.67
High (≥472 ppb-months) 8 (2.2) 3 (4.2) 1.99 (0.42-7.47) 0.34 1.50 (0.30-6.11) 0.57
Cumulative vinyl chloride
No exposure 356 (95.7) 67 (94.4) 1.00 (ref.)   1.00 (ref.)  
Low (>0- <60 ppb-months) 8 (2.2) 2 (2.8) 1.33 (0.19-5.89) 0.69 0.94 (0.13-4.38) 0.99
High (≥60 ppb-months) 8 (2.2) 2 (2.8) 1.33 (0.19-5.89) 0.69 1.19 (0.16-5.89) 0.81
Cumulative TVOCb
No exposure 258 (84.9) 46 (64.8) 1.00 (ref.)   1.00 (ref.)  
Low (>0- <168 ppb-months) 57 (15.3) 14 (19.7) 1.38 (0.69-2.64) 0.35 1.18 (0.57-2.33) 0.64
High (≥168 ppb-months) 57 (15.3) 11 (15.5) 1.08 (0.51-2.18) 0.81 0.82 (0.37-1.72) 0.63
Monthly average PCE
No exposure 357 (96.0) 67 (94.4) 1.00 (ref.)   1.00 (ref.)  
Low (>0- < 2 ppb) 8 (2.2) 2 (2.8) 1.33 (0.19-5.90) 0.69 0.91 (0.13-4.21) 0.96
High (≥2 ppb) 7 (1.9) 2 (2.8) 1.52 (0.21-7.00) 0.59 1.47 (0.18-7.91) 0.65
Monthly average TCE
No exposure 258 (69.4) 46 (64.8) 1.00 (ref.)   1.00 (ref.)  
Low (>0- <17.5 ppb) 57 (15.3) 8 (11.3) 0.79 (0.33-1.71) 0.58 1.02 (0.42-2.30) 0.93
High (≥17.5 ppb) 57 (15.3) 17 (23.9) 1.67 (0.88-3.10) 0.12 0.97 (0.47-1.94) 0.94
Monthly average benzene
No exposure 260 (69.9) 46 (64.8) 1.00 (ref.)   1.00 (ref.)  
Low (>0- < 0.4 ppb) 56 (15.1) 9 (12.7) 0.91 (0.40-1.92) 0.83 1.23 (0.52-2.72) 0.61
High (≥0.4 ppb) 56 (15.1) 16 (22.5) 1.61 (0.83-3.03) 0.15 0.87 (0.42-1.78) 0.72
Monthly average DCE
No exposure 356 (95.7) 67 (94.4) 1.00 (ref.)   1.00 (ref.)  
Low (>0- < 94 ppb) 8 (2.2) 2 (2.8) 1.33 (0.20-5.90) 0.69 0.88 (0.12-4.01) 0.92
High (≥94 ppb) 8 (2.2) 2 (2.8) 1.33 (0.20-5.90) 0.69 1.32 (0.17-6.77) 0.73
Monthly average vinyl chloride
No exposure 356 (95.7) 67 (94.4) 1.00 (ref.)   1.00 (ref.)  
Low (>0- <3.4 ppb) 8 (2.2) 2 (2.8) 1.33 (0.20-5.90) 0.69 0.94 (0.13-4.37) 0.99
High (≥3.4 ppb) 8 (2.2) 2 (2.8) 1.33 (0.20-5.90) 0.69 1.19 (0.16-5.89) 0.81
Monthly average TVOCb
No exposure 258 (69.4) 46 (64.8) 1.00 (ref.)   1.00 (ref.)  
Low (>0- <18 ppb) 58 (15.6) 9 (12.7) 0.87 (0.38-1.83) 0.75 1.15 (0.49-2.51) 0.72
High (≥18 ppb) 56 (15.1) 16 (22.5) 1.60 (0.83-3.01) 0.16 0.89 (0.43-1.80) 0.76
  1. aadjusted for age at diagnosis, race, and service in Vietnam; bsum of the amount of exposure to PCE, TCE, benzene, DCE, and vinyl chloride