Associations of genetic variations in EYA4, GRHL2 and DFNA5 with noise-induced hearing loss in Chinese population: a case- control study

Table 1 Distributions of allele and genotype in the subjects of NIHLand normal hearing groups

gene	SNP	A1/A2	maf	case^a	control^a
EYA4	rs3777781	A/T	0.430	72/235/166	98/236/137
	rs212769	A/G	0.141	8/129/336	5/112/354
	rs3777849^#	A/G	0.353	70/175/228	85/182/204
	rs465147	T/C	0.010	0/7/465	0/11/459
	rs3777860	A/G	0.355	62/217/194	57/215/200
GRHL2	rs666026	G/T	0.298	46/204/222	40/186/244
	rs471757^#	T/C	0.431	89/217/167	105/208/158
	rs10955255	G/A	0.220	16/164/292	23/173/275
	rs682769^#	A/G	0.191	10/155/308	11/163/297
	rs1981361	A/G	0.289	36/200/237	34/205/232
DFNA5	rs2521758	G/T	0.019	0/14/458	1/20/450
	rs2521768	C/T	0.209	19/148/305	27/155/289

^aPresented as the order of A1A1/A1A2/A2A2. A1: the minor allele; A2: the major allele
^# P values < 0.05 after Hardy-Weinberg equilibrium tests

ISSN: 1476-069X