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Table 4 Estimated change of mitochondrial 8-OHdG in cord blood associated with PM10 and PM2.5 exposure during pregnancy (n = 293)

From: Mitochondrial oxidative DNA damage and exposure to particulate air pollution in mother-newborn pairs

 

PM10 a

PM2.5 a

Time window

Percent changeb

95 % CI

p-Value

Percent changeb

95 % CI

p-Value

Trimester 1 (1–13w)

23.0

5.9, 42.8

0.007

15.8

−2.4, 37.6

0.09

Trimester 2 (14–26w)

16.6

1.8, 33.5

0.03

12.1

−5.7, 33.1

0.19

Trimester 3 (27w-delivery)

−13.4

−26.2, 1.7

0.08

−14.9

−29.4, 2.6

0.09

Entire pregnancy

8.7

−2.0, 20.6

0.11

3.1

−7.0, 14.4

0.56

  1. aThe model is adjusted for maternal age, gestational age, smoking status, maternal education, alcohol consumption during pregnancy, season at conception, gender, and date of delivery.
  2. bThe effect size is calculated as a relative percent change for an IQR increment in PM10 or PM2.5 exposure (μg/m3) at the mother’s residence during the different time windows. The IQR for the different time windows for PM10 and PM2.5 is given in Table 2
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Environmental Health

ISSN: 1476-069X